Results 201 to 210 of about 62,676 (260)

Fruit respiration: putting alternative pathways into perspective

New Phytologist, Volume 250, Issue 1, Page 54-73, April 2026.
Summary Over the past century, research has significantly advanced our understanding of fruit respiration, from (eco)physiological processes to molecular mechanisms. This review focuses on the functional relevance and regulatory roles of mitochondrial alternative respiratory pathways (ARPs) during fruit growth and ripening.
Ariadna Iglesias‐Sanchez, Sergio García‐Carbonell, Alisdair R. Fernie, Marta Pujol, Igor Florez‐Sarasa   +4 more
wiley   +1 more source

STING synergizes with TOX suppressing HO-1 expression to trigger ferroptosis in tumor-infiltrating CD8+ T cell and immunotherapy resistance. [PDF]

Nat Commun
Zhu Q, Zhang JB, Nie CP, Liu XF, Zhan LP, Li M, Zeng XL, He J, Huang H, Xia XJ, Gao S, Zhang XS, Li J.   +12 more
europepmc   +1 more source

CSDE1 Drives Glycolysis and the Progression of Prostate Cancer Through RAC1‐Dependent RAS/MAPK Activation

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
The mechanism by which CSDE1 promotes prostate cancer progression through RAC1‐dependent RAS/MAPK activation and enhanced glycolysis. ABSTRACT Prostate cancer (PCa) remains a leading cause of cancer‐related morbidity and mortality among men, necessitating the elucidation of molecular drivers behind its progression.
Zhen Yin, Zefeng Wang, Wei Gong, Zitao Wang, Zongze Li, Lizhe Xu, Jinzhuo Ning, Lei Gao, Tiejun Pan, Weimin Yu, Yu Zhou, Jinbo Sun, Fan Cheng   +12 more
wiley   +1 more source

Development of a p62 biodegrader for autophagy targeted degradation. [PDF]

Nat Commun
Thiel Z, Marcellin D, Manneville C, Goretzki B, Egger L, Maher R, Siccardi N, Torres L, Probst A, Müller CS, George N, Vogel M, Sinterhauf S, Lavoisier A, Choi JY, Forcellino L, Landshammer A, Hauck P, Be C, Villard F, Gutmann S, Meyer M, Freuler F, Hinniger A, Fernández C, Chau S, Patoor M, Sansig G, Mitchell G, Nyfeler B.   +29 more
europepmc   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

International Journal of Cancer, Volume 158, Issue 6, Page 1464-1480, 15 March 2026.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

Mitochondrial connexin 43 modulates metabolic stress adaptation in glioma cell lines. [PDF]

Cell Commun Signal
Gervasi A, Denaro S, D'Aprile S, Potokar M, Jorgačevski J, Zorec R, Tibullo D, Zappalà A, Amorini AM, Parenti R, Vicario N.   +10 more
europepmc   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

Idiopathic Spinal Cord Herniation With Severe Adhesions Treated Using the Hammock Method: A Case Report. [PDF]

Cureus
Aizawa K, Tatsumura M, Okuwaki S, Nagashima K, Takeuchi Y, Funayama T.   +5 more
europepmc   +1 more source

Mito

, 2010
openaire   +1 more source