Results 291 to 300 of about 216,996 (340)

Free Fatty Acids Induce Apoptosis of Mammary Epithelial Cells of Ketotic Dairy Cows via the Mito-ROS/NLRP3 Signaling Pathway.

Journal of Agricultural and Food Chemistry, 2023
Early lactation increases metabolic stress in ketotic dairy cows, leading to mitochondrial damage, apoptosis, and inflammatory response in mammary epithelial cells.
R. Chang, Hongdou Jia, Zhihao Dong, Qiushi Xu, Lei Liu, Zolzaya Majigsuren, Tugsjargal Batbaatar, Chuang Xu, Qing Yang, Xu-Dong Sun   +9 more
semanticscholar   +1 more source

Mitochondria-Targeted Gene Silencing Facilitated by Mito-CPDs.

Chemistry, 2023
Mitochondrial DNA (mtDNA) plays an essential role in maintaining normal cellular activities. Its heteroplasmic mutations are known to cause various genetic diseases.
Wenjie Lang, W. Tan, Bizhong Zhou, Yuli Zhuang, Bei Zhang, Linye Jiang, Shao Q. Yao, Jingyan Ge   +7 more
semanticscholar   +1 more source

Mito-Q supplementation of in vitro maturation or in vitro culture medium improves maturation of buffalo oocytes and developmental competence of cloned embryos by reducing ROS production.

Animal Reproduction Science, 2023
Mito-Q is a well-known mitochondria-specific superoxide scavenger. To our knowledge, the effect of Mito-Q on buffalo oocyte maturation and developmental competency of cloned embryos has not been examined.
Maninder Sharma, M. Punetha, Sheetal Saini, Suman Chaudhary, Sujata Jinagal, Swati Thakur, Pradeep Kumar, Rajesh Kumar, R. K. Sharma, P. S. Yadav, Dharmendra Kumar   +10 more
semanticscholar   +1 more source

Proteomic analysis reveals the potential positive effects of Mito-TEMPO on ram sperm motility and fertility during cryopreservation.

Theriogenology, 2023
The aim of this study was to investigate the effects of mitochondria-targeted antioxidant Mito-TEMPO on the protein profile of ram sperm during cryopreservation and evaluate the cryoprotective roles of Mito-TEMPO on ram sperm quality and fertilization ...
Lei Shi, Juan-Juan Shi, Jingjuan Feng, Pengcheng Zhang, You-She Ren   +4 more
semanticscholar   +1 more source

MITO END-3: Efficacy of Avelumab immunotherapy according to molecular profiling in first-line endometrial cancer therapy.

Annals of Oncology
BACKGROUND Immunotherapy combined with chemotherapy significantly improves progression-free survival compared to first-line chemotherapy alone in advanced endometrial cancer, with a much larger effect size in microsatellite-instability high (MSI-H) cases.
S. Pignata, D. Califano, D. Lorusso, L. Arenare, M. Bartoletti, U. de Giorgi, C. Andreetta, C. Pisano, G. Scambia, D. Lombardi, A. Farolfi, S. Cinieri, A. Passarelli, V. Salutari, C. de Angelis, C. Mignogna, D. Priolo, E. Capoluongo, S. Tamberi, G. L. Scaglione, V. Arcangeli, R. De Cecio, G. Scognamiglio, F. Greco, A. Spina, M. Turinetto, D. Russo, V. Carbone, C. Casartelli, C. Schettino, F. Perrone   +30 more
semanticscholar   +1 more source

Mito-tempo alleviates ox-LDL-provoked foam cell formation by regulating Nrf2/NLRP3 signaling.

Bioscience, biotechnology and biochemistry
Our previous studies have demonstrated that Mito-Tempol (also known as 4-hydroxy-Tempo), a mitochondrial reactive oxygen species (ROS) scavenger, alleviates oxidized low-density lipoprotein (ox-LDL)-triggered foam cell formation.
Zhen-Yu Huang, Zhaoli Zhou, Ying-Bo Ma, Yaomin Hu   +3 more
semanticscholar   +1 more source

Effects of freezing extender supplementation with mitochondria-targeted antioxidant Mito-TEMPO on frozen-thawed rooster semen quality and reproductive performance.

Animal Reproduction Science, 2020
Rooster semen cryopreservation is a useful method to utilize semen samples for artificial insemination in commercial flocks, but with use of the freezing-thawing process there is a reduction in the quality and fertilization capacity of rooster ...
R. Masoudi, N. Asadzadeh, M. Sharafi
semanticscholar   +1 more source

Supplementation of ram's semen extender with Mito-TEMPO I: Improvement in quality parameters and reproductive performance of cooled-stored semen.

Cryobiology, 2020
Supplementation of cooling medium with some antioxidants could be a helpful way to improve sperm quality during chilling process. The current study was aimed to assess the influence of using Mito-TEMPO in cooling medium on quality parameters and ...
F. Zarei, H. D. Kia, R. Masoudi, Gholamali Moghaddam, M. Ebrahimi   +4 more
semanticscholar   +1 more source

Mito-communications

Mitochondrial DNA, 2009
Simon Y W, Ho, Robert, Lanfear
  +11 more sources

A mirage of cryptic species: genomics uncover striking mito-nuclear discordance in the butterfly Thymelicus sylvestris.

Molecular Ecology, 2019
Mitochondrial DNA (mtDNA) sequencing has led to an unprecedented rise in the identification of cryptic species. However, it is widely acknowledged that nuclear DNA (nuDNA) sequence data are also necessary to properly define species boundaries.
Joan C. Hinojosa, Darina Koubínová, M. Szenteczki, Camille Pitteloud, V. Dincă, N. Alvarez, R. Vilà   +6 more
semanticscholar   +1 more source