Results 151 to 160 of about 2,143,132 (361)

Characteristics of different lipid droplet-mitochondrial contacts patterns during lipid droplet metabolism in T2DM-induced MASLD

open access: yesScientific Reports
Mitochondrial function is crucial for hepatic lipid metabolism. Current research identifies two types of mitochondria based on their contact with lipid droplets: peridroplet mitochondria (PDM) and cytoplasmic mitochondria (CM).
Ye Xu   +11 more
doaj   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

open access: yesAdvanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko   +16 more
wiley   +1 more source

Mechanism and regulation of mitophagy in liver diseases: a review

open access: yesFrontiers in Cell and Developmental Biology
Mitochondria are vital for the proper operation of healthy eukaryotic cells. Mitophagy, a specialized form of autophagy that targets damaged or surplus mitochondria, plays a key role in both the normal functioning and disease-related processes within the
Sen Liu   +12 more
doaj   +1 more source

Effects of Hyperbaric Hypoxia on Some Enzyme Systems in the Mammalian Liver [PDF]

open access: yes, 1978
The metabolic effects of hypobaric hypoxic stress on the mammalian liver were studied. The lactate dehydrogenase (LDH) and succinate dehydrogenase (SDH) activity of mouse liver homogenates were measured after exposure to an equivalent altitude of 36,000 ...
Baeyens, Dennis A., Meier, M. J.
core   +2 more sources

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton   +2 more
wiley   +1 more source

Redox-dependent gating of VDAC by mitoNEET. [PDF]

open access: yes, 2019
MitoNEET is an outer mitochondrial membrane protein essential for sensing and regulation of iron and reactive oxygen species (ROS) homeostasis. It is a key player in multiple human maladies including diabetes, cancer, neurodegeneration, and Parkinson's ...
Bai, Fang   +8 more
core  

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

open access: yesAdvanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing   +5 more
wiley   +1 more source

Biosynthesis and assembly of mitochondrial proteins [PDF]

open access: yes, 1983
A Scarpa   +75 more
core   +1 more source

Membrane Semi‐Permeability and Ion Selectivity in Chemiosmosis: Open Systems Volume Dependence of Electrolyte Chemistry

open access: yesAdvanced Materials Interfaces, EarlyView.
Very small cellular compartments can break electroneutrality and harness proton gradients without active transport structures, whereas larger volumes cannot, underscoring why life's critical energy processes are confined in microscopic spaces. ABSTRACT The effect of pH changes in external ionic solutions on liposomes entrapping non‐permeable weak acid ...
Josep M. Ribó   +4 more
wiley   +1 more source

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