Results 291 to 300 of about 1,007,169 (424)

Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy

open access: yesAdvanced Science, EarlyView.
Selenium electrophilic center intelligently responds to different ratio of biological electron donors/receptors in cancer cells and normal cells to achieve highly effective and less toxic chemotherapy. Abstract Designing drugs to intelligently respond to different ratio of biological electron donors/receptors in cancer cells and normal cells is a ...
Xiaoyu Qin   +8 more
wiley   +1 more source

Delivery of Human iPSC‐Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells

open access: yesAdvanced Science, EarlyView.
Human induced pluripotent stem cell‐derived retinal pigment epithelial (hiPSC‐RPE) cells, cultured on a clinically relevant PDLLA scaffold, are transplanted into immunosuppressed minipigs. The study demonstrates the viability, integration, and preservation of RPE‐specific features without gliosis or neuroinflammation, supporting their potential as a ...
Anna Macečková Brymová   +27 more
wiley   +1 more source

Structural and functional studies of the VAPB-PTPIP51 ER-mitochondria tethering proteins in neurodegenerative diseases. [PDF]

open access: yesActa Neuropathol Commun
Blair K   +8 more
europepmc   +1 more source

Studies on Stability of Rat Liver Mitochondria

open access: hybrid, 1959
Marie N. Lipsett, Laurence M. Corwin
openalex   +1 more source

Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU‐EMRE Assembly

open access: yesAdvanced Science, EarlyView.
Berberine, a safe and FDA‐approved drug, is identified as a novel mitochondrial calcium uniporter (MCU) inhibitor. By disrupting MCU‐EMRE interaction, Berberine prevents mitochondrial calcium overload and protects against ischemia/reperfusion injury, offering a promising therapeutic strategy for diseases linked to mitochondrial calcium dysregulation ...
Haixin Zhao   +17 more
wiley   +1 more source

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