Results 281 to 290 of about 589,060 (317)
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Seminars in Liver Disease, 1998
Recent advances in our understanding of the structure and function of mitochondria have led to the recognition that inherited and acquired mitochondrial dysfunction may be responsible for diseases affecting the liver and other organ systems. Mitochondrial health may also determine hepatocyte survival in other hepatic disorders not directly related to ...
W R, Treem, R J, Sokol
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Recent advances in our understanding of the structure and function of mitochondria have led to the recognition that inherited and acquired mitochondrial dysfunction may be responsible for diseases affecting the liver and other organ systems. Mitochondrial health may also determine hepatocyte survival in other hepatic disorders not directly related to ...
W R, Treem, R J, Sokol
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Nature Genetics, 2001
An elegant set of mouse crosses has been used to identify a mitochondrial variant that interacts with a nuclear locus on chromosome 10, Ahl, to modify age-related hearing loss. This discovery sets the stage for the identification of factors that modify expression levels and variability of human hearing impairments.
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An elegant set of mouse crosses has been used to identify a mitochondrial variant that interacts with a nuclear locus on chromosome 10, Ahl, to modify age-related hearing loss. This discovery sets the stage for the identification of factors that modify expression levels and variability of human hearing impairments.
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The Biogenesis of Mitochondria
Annual Review of Biochemistry, 1970INTRODUCTION 251 MITOCHONDRIAL DNA . . . . . . . . . . . . . . . . . . .. . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 SYNTHESIS AND TURNOVER OF MITOCHONDRIAL DNA . . . . .. . . .. . .. ... . .. ... 256 MITOCHONDRIAL RNA AND MITOCHONDRIAL RIBOSOMES 257 SYNTHESIS OF MITOCHONDRIAL RNA . . . . . . . . . . . . . . . . . . . . . . . . .
M, Ashwell, T S, Work
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Journal of Molecular Evolution, 1975
The endosymbiont and episome theories about the origin of mitochondria are reviewed. Biochemical and genetic data, relevant to these theories are discussed. An alternative theory is also proposed; this theory is that nuclear and mitochondrial DNAs developed from compartmentalized duplicate prokaryote DNAs.
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The endosymbiont and episome theories about the origin of mitochondria are reviewed. Biochemical and genetic data, relevant to these theories are discussed. An alternative theory is also proposed; this theory is that nuclear and mitochondrial DNAs developed from compartmentalized duplicate prokaryote DNAs.
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Nature, 1967
THE concept of intracellular pH depends on the assumption that the cell is either not divided into compartments, or that the volumes of the compartments are large enough to contain a statistically meaningful number of hydrogen ions, the “intracellular pH” in this case being a mean of the pH values in the various compartments.
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THE concept of intracellular pH depends on the assumption that the cell is either not divided into compartments, or that the volumes of the compartments are large enough to contain a statistically meaningful number of hydrogen ions, the “intracellular pH” in this case being a mean of the pH values in the various compartments.
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Biochemistry (Moscow), 2020
Cytotoxic T lymphocytes and natural killer cells eliminate infected cells from the organism by triggering programmed cell death (apoptosis). The contents of the lytic granules of killer cells, including pore-forming proteins perforins and proteolytic enzymes granzymes, are released with the following penetration of the released proteins into the target
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Cytotoxic T lymphocytes and natural killer cells eliminate infected cells from the organism by triggering programmed cell death (apoptosis). The contents of the lytic granules of killer cells, including pore-forming proteins perforins and proteolytic enzymes granzymes, are released with the following penetration of the released proteins into the target
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Science, 1965
Recognizable mitochondria were detected in the nucleus of a leukemic cell. It is suggested that passage through enlarged nuclear pores, incorporation within a pinched off invagination, or inclusion within the nuclear envelope at telophase may have been responsible for this unusual event.
D, Brandes, B H, Schofield, E, Anton
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Recognizable mitochondria were detected in the nucleus of a leukemic cell. It is suggested that passage through enlarged nuclear pores, incorporation within a pinched off invagination, or inclusion within the nuclear envelope at telophase may have been responsible for this unusual event.
D, Brandes, B H, Schofield, E, Anton
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Mitochondria in Postconditioning
Antioxidants & Redox Signaling, 2011Several signal transduction pathways are activated by cardioprotective stimuli, including ischemic or pharmacological postconditioning. These pathways converge on a common target, the mitochondria, and cardioprotection by postconditioning is associated with preserved mitochondrial function after ischemia/reperfusion.
Böngler, Kerstin +2 more
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Mitochondria, NO and neurodegeneration
Biochemical Society Symposia, 1999A role for mitochondrial dysfunction in neurodegenerative disease is gaining increasing support. Mitochondrial dysfunction may be linked to neurodegenerative diseases through a variety of different pathways, including free-radical generation, impaired calcium buffering and the mitochondrial permeability transition.
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