Results 271 to 280 of about 902,846 (308)

Mitophagy in neuronal health and disease: from mechanisms to neurodegeneration. [PDF]

J Clin Invest
Basak B, Riley JF, Nataraj NM, Holzbaur EL.   +3 more
europepmc   +1 more source

Airway administered artificial mitochondria-enriched nanovesicles for efficient and selective mitochondria transfer to intervene in pulmonary fibrosis. [PDF]

Nat Commun
Zhang J, Fu S, Wang J, Wu H, Li Z, Lin R, Sun H, Choe S, Kong Y, Xu D, Wang J, Gu Z, Gao J, Zhang T.   +13 more
europepmc   +1 more source

Outer membrane vesicles secreted by avian pathogenic Escherichia coli promote intracellular survival in macrophages and systemic infection by regulating mitophagy through the MSTRG.11745.1/gga-miR-15b-5p/TNFAIP3 axis. [PDF]

Poult Sci
Gao J, Li Z, Cui T, Shao Y, Sun J, Wang Z, Song X, Cheng Z, Tu J.   +8 more
europepmc   +1 more source

Advances in mitochondrial compartmentalization for terpenoid synthesis in <i>Saccharomyces cerevisiae</i>. [PDF]

Front Bioeng Biotechnol
Zheng C, Ma T.
europepmc   +1 more source

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Mitochondria in Health, Disease, and Ageing.

Physiological Reviews, 2023
Mitochondria are well-known as organelles responsible for the maintenance of cellular bioenergetics through the production of ATP. While oxidative phosphorylation may be their most important function, mitochondria are also integral for the synthesis of ...
John S. Harrington, S. Ryter, M. Plataki, D. Price, Augustine M. K. Choi   +4 more
semanticscholar   +1 more source

The power and potential of mitochondria transfer

Nature, 2023
Mitochondria are believed to have originated through an ancient endosymbiotic process in which proteobacteria were captured and co-opted for energy production and cellular metabolism.
Nicholas Borcherding, Jonathan R. Brestoff   +1 more
semanticscholar   +1 more source

Mito‐Bomb: Targeting Mitochondria for Cancer Therapy

Advances in Materials, 2021
Cancer has been one of the most common life‐threatening diseases for a long time. Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) have limited effects due to drug resistance, unsatisfactory treatment efficiency, and
Xiaolu Guo, Nai-Di Yang, Wenhui Ji, Hang Zhang, Xiao Dong, Zhiqiang Zhou, Lin Li, Han-Ming Shen, Shao Q. Yao, Wei Huang   +9 more
semanticscholar   +1 more source

The role of mitochondria in NLRP3 inflammasome activation.

Molecular Immunology, 2018
The NLRP3 inflammasome is a multiprotein platform which is activated upon cellular infection or stress. Its activation leads to caspase-1-dependent secretion of proinflammatory cytokines like interleukin-1β (IL-1β) and IL-18, and an inflammatory form of ...
Qiuyu Liu, Dan-Yan Zhang, D. Hu, Xiang-Mei Zhou, Yang Zhou   +4 more
semanticscholar   +1 more source

Mitochondria as playmakers of apoptosis, autophagy and senescence.

Seminars in Cell and Developmental Biology, 2020
Mitochondria are the key energy-producing organelles and cellular source of reactive species. They are responsible for managing cell life and death by a balanced homeostasis passing through a network of structures, regulated principally via fission and ...
M. Abate, Agostino Festa, Michela Falco, A. Lombardi, A. Luce, A. Grimaldi, S. Zappavigna, P. Sperlongano, Carlo Irace, M. Caraglia, Gabriella Misso   +10 more
semanticscholar   +1 more source