Results 261 to 270 of about 591,098 (317)

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

Mitochondrial dysfunction in Alzheimer's disease: targeting the powerhouse with nanomedicine. [PDF]

Front Pharmacol
Kang C, Zhou X, Li B, Li J.
europepmc   +1 more source

Hippocampal CA1 and CA2 dendritic compartment-specific differences in mitochondrial form and function. [PDF]

Prog Neurobiol
Alsalman M, Turner L, Pannoni K, Tarannum R, Desai R, Swanger SA, Farris S.   +6 more
europepmc   +1 more source

Redox control at the ER-mitochondria interface in kidney transplantation: MAM-centered stress signaling and translational organoid platforms. [PDF]

Redox Biol
Kuang B, Han L, Tan S, Tan S, Bou S, Zhao Y, Li Y, Yu J, Gong N.   +8 more
europepmc   +1 more source

Mitochondrial Regulation of the NLRP3 Inflammasome in Diabetic Kidney Disease: From Mechanisms to Therapeutic Strategies. [PDF]

Int J Mol Sci
Chen X, Wu Z, Yu K, Zhang J, Di H.
europepmc   +1 more source

The Role of Mitochondria in Polycystic Kidney Disease. [PDF]

Int J Mol Sci
Wang Y, Mao J, Liu F.
europepmc   +1 more source

Mitochondria-Associated mRNAs Restore ATP During Oxidative Stress via Cytosolic Translation. [PDF]

Antioxidants (Basel)
Back DB, Hamanaka G, Park JH, Ishikane S, Tanaka M, Nakano T, Nakamura Y, Hayakawa K.   +7 more
europepmc   +1 more source