Results 231 to 240 of about 941,236 (333)

Probing Cellular Activity Via Charge‐Sensitive Quantum Nanoprobes

Advanced Materials, EarlyView.
A new quantum sensing modality detects shifts in zero‐field splitting caused by charge rearrangement with diamond nanocrystals in response to cellular activity. These electric‐field‐driven effects provide an alternative to temperature‐based interpretations, enabling real‐time, single‐cell readout of inflammation.
Uri Zvi, Shivam Mundhra, David Ovetsky, Qing Chen, Aidan R. Jones, Stella Wang, Maria J. Román‐Vazquez, Marie Kim, Udoka M. Ibeh, Michele Ferro, Kunle Odunsi, Marina C. Garassino, Michael E. Flatté, Melody A. Swartz, Denis R. Candido, Aaron Esser‐Kahn, Peter C. Maurer   +16 more
wiley   +1 more source

Mitochondrial DNA Mutations and Epigenetic Regulation in Type 2 Diabetes Mellitus Development. [PDF]

Br J Biomed Sci
Koh MX, Simpson T, Zain SM, Ayub Q, Cheah HL, Pan Y, Cheng SH, Pung YF.   +7 more
europepmc   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Mitochondrial DNA Variation of the Striped Hyena (Hyaena hyaena) in Algeria and Further Insights into the Species' Evolutionary History. [PDF]

Genes (Basel)
Derouiche L, Rodrigues M, Benameur-Hasnaoui H, Aissa RH, Hassan-Beigi Y, Madjdzadeh SM, Amr Z, Cokayne A, Vercammen P, Fernandes CR.   +9 more
europepmc   +1 more source

Differentiation of four strains of Chinese soft-shelled turtle (Pelodiscus sinensis) based on high-resolution melting analysis of single nucleotide polymorphism sites in mitochondrial DNA

, 2015
Haojian Zhang, C. Zhang, Xiaolan Xu, Jia-shi Zhu, Ziyan He, Junjie Shao   +5 more
openalex   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

Mitochondrial DNA Dysfunction in Cardiovascular Diseases: A Novel Therapeutic Target. [PDF]

Antioxidants (Basel)
Xiang M, Yang M, Zhang L, Ouyang X, Sarapultsev A, Luo S, Hu D.   +6 more
europepmc   +1 more source

Mitochondria‐Specific Protein Delivery by Protease‐Triggered Release in Plants with Single‐Walled Carbon Nanotubes

Advanced Materials Technologies, EarlyView.
Polymer‐coated carbon nanotubes were engineered as protease‐responsive nanocarriers for protein delivery in intact plants. GFP cargo can be released by cytosolic phytaspase cleavage and subsequently targeted to mitochondria via an N‐terminal sequence, enabling controlled intracellular protein delivery without tissue damage and demonstrating stable ...
Simon Sau Yin Law, Takehiro Suzuki, Tsuyohiko Fujigaya, Keiji Numata   +3 more
wiley   +1 more source

Author Correction: Ribonucleotide incorporation into mitochondrial DNA drives inflammation. [PDF]

Nature
Bahat A, Milenkovic D, Cors E, Barnett M, Niftullayev S, Katsalifis A, Schwill M, Kirschner P, MacVicar T, Giavalisco P, Jenninger L, Clausen AR, Paupe V, Prudent J, Larsson NG, Rogg M, Schell C, Muylaert I, Larsson E, Nolte H, Falkenberg M, Langer T.   +21 more
europepmc   +1 more source