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Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2022
Hypoergos-energy deficiency, i.e., a mismatch between the body's (tissue, organ, cell) need for energy and the limited amount of macroergs (ATP) that can currently be used to maintain the structural integrity and functional activity of a tissue or organ.
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Hypoergos-energy deficiency, i.e., a mismatch between the body's (tissue, organ, cell) need for energy and the limited amount of macroergs (ATP) that can currently be used to maintain the structural integrity and functional activity of a tissue or organ.
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Mitochondrial dysfunction in aging
Ageing Research Reviews, 2023Aging is a complex process that features a functional decline in many organelles. Although mitochondrial dysfunction is suggested as one of the determining factors of aging, the role of mitochondrial quality control (MQC) in aging is still poorly understood.
Ying Guo +8 more
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Mitochondrial dysfunction in sepsis
Current Infectious Disease Reports, 1999The current mainstream view of organ failure induced by sepsis revolves around inflammation and loss of vascular control. However, there has been a resurgence in interest in bioenergetic failure due to mitochondrial dysfunction. This concept is not new--studies date back 30 years; however, the data have been highly conflicting with findings of either ...
M, Singer, D, Brealey
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Mitochondrial dysfunction in ALS
Progress in Neurobiology, 2012In the present article, we review the many facets of mitochondrial dysfunction in amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease due to loss of upper motor neurons in cerebral cortex and lower motor neurons in brainstem and spinal cord.
Cozzolino Mauro, Carri Maria Teresa
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Mitochondrial dysfunction in epilepsy
Mitochondrion, 2012Mitochondrial dysfunction has been identified as one potential cause of epileptic seizures. Impaired mitochondrial function has been reported for the seizure focus of patients with temporal lobe epilepsy and Ammon's horn sclerosis and of adult and immature animal models of epilepsy.
Jaroslava, Folbergrová, Wolfram S, Kunz
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Mitochondrial dysfunction in cancer
Mitochondrion, 2004Nearly a century of scientific research has revealed a number of notable differences in the structure and function of mitochondria between normal and cancer cells, including differences in metabolic activity, molecular composition, and mtDNA sequence.
Josephine S, Modica-Napolitano +1 more
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