Results 281 to 290 of about 388,773 (307)

Mitochondrial Dysfunction in Autism

Seminars in Pediatric Neurology, 2013
Using data of the current prevalence of autism as 200:10,000 and a 1:2000 incidence of definite mitochondrial (mt) disease, if there was no linkage of autism spectrum disorder (ASD) and mt disease, it would be expected that 1 in 110 subjects with mt disease would have ASD and 1 in 2000 individuals with ASD would have mt disease.
Agustín, Legido, Reena, Jethva, Michael J, Goldenthal   +2 more
openaire   +2 more sources

Mitochondrial Dysfunction and Glaucoma

Journal of Glaucoma, 2009
Glaucoma is increasingly recognized as a neurodegenerative disorder, characterized by the accelerated loss of retinal ganglion cells (RGCs) and their axons. Open angle glaucoma prevalence and incidence increase exponentially with increasing age, yet the pathophysiology underlying increasing age as a risk factor for glaucoma is not well understood ...
George Y X, Kong, Nicole J, Van Bergen, Ian A, Trounce, Jonathan G, Crowston   +3 more
openaire   +2 more sources

Mitochondrial dysfunction in osteoarthritis

Mitochondrion, 2004
In osteoarthritis (OA) a time or age dependent process leads to aberrant cartilage structure which is characterized by reduced number of chondrocytes, loss of existing cartilage extracellular matrix, the production of matrix with abnormal composition and pathologic matrix calcification.
Francisco J, Blanco, Maria J, López-Armada, Emilia, Maneiro   +2 more
openaire   +2 more sources

Mitochondrial Dysfunction in Epilepsy

Seminars in Pediatric Neurology, 2013
Epilepsy is the most common neurologic disorder worldwide and is characterized by recurrent unprovoked seizures. The mitochondrial (mt) respiratory chain is the final common pathway for cellular energy production through the process of oxidative phosphorylation.
Divya S, Khurana, Ignacio, Valencia, Michael J, Goldenthal, Agustín, Legido   +3 more
openaire   +2 more sources

Mitochondrial Dysfunction in Hepatitis C

Journal of Clinical Gastroenterology, 2005
Chronic hepatitis C induces a state of hepatic oxidative stress that is more pronounced than that present in many other inflammatory liver diseases. This review summarizes recent information that the hepatitis C virus (HCV) core protein plays an important role in this phenomenon.
Masaaki, Korenaga, Michiari, Okuda, Kazuhiro, Otani, Ting, Wang, Yanchun, Li, Steven A, Weinman   +5 more
openaire   +2 more sources

Mitochondrial dysfunction in bipolar disorder

2010
Phosphorus magnetic resonance spectroscopic studies in bipolar disorder revealed altered brain energy metabolism resembling that of chronic progressive external ophthalmoplegia (CPEO). Mood disorder is one characteristic symptom in several families of CPEO caused by mutations of three genes, ANT1, Twinkle, and POLG.
openaire   +3 more sources

Cyclosporin and mitochondrial dysfunction

Biochemical Society Transactions, 1990
O, McGuinness, M, Crompton
openaire   +2 more sources

Blood biomarkers for assessment of mitochondrial dysfunction: An expert review

Mitochondrion, 2022
Wouter H G Hubens, Irenaeus F M De Coo, H J M Smeets   +2 more
exaly  

Site-specific mitochondrial dysfunction in neurodegeneration

Mitochondrion, 2022
Shon A Koren, Andrew P Wojtovich
exaly  

Mitochondrial dysfunction-targeted nanosystems for precise tumor therapeutics

Biomaterials, 2023
Yanli Zhao
exaly