Results 271 to 280 of about 13,400,035 (354)

Splice-switching of the oncogenic BCS1L isoform suppresses ovarian cancer progression by disrupting mitochondrial function. [PDF]

Cell Death Dis
Xu M, Wang Z, Yang S, Li G, Zhang X, Zhao L, Yang L, Qiu C, Feng X, Zhang K, Liu B, Wei JJ, Li Y, Liu G, Cui B, Qin J, Liu Z.   +16 more
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

SS-31 improves the quality of maternally aged oocytes by ameliorating mitochondrial function and metabolism. [PDF]

J Ovarian Res
Xiong D, Zhang Y, Wei J, Wang L, Zhang G, Yu L, Zeng J, Liu W.   +7 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Influence of right ventricular pacing on mitochondrial function in adults. [PDF]

Physiol Rep
Gumrai P, Nantsupawat T, Apaijai N, Phrommintikul A, Prasertwitayakij N, Chattipakorn SC, Chattipakorn N, Wongcharoen W.   +7 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

A noncanonical polyamine from bacteria antagonizes host mitochondrial function. [PDF]

Nat Commun
Nauta KM, Gates DR, Weiland M, Mechan-Llontop ME, Wang X, Isaguirre C, Gendjar MR, Cooper J, Barton SF, Nguyen KP, Sheldon RD, Krawczyk CM, Burton NO.   +12 more
europepmc   +1 more source

Counterintuitive Fluorescence Blue Shift in Symmetry Breaking Dicationic Bis(indolium) with Two‐Photon Absorption Properties for NIR Living Cell Imaging

Advanced Materials, EarlyView.
Highly water‐soluble dicationic bis(indolium) dyes have been prepared, showing excellent two‐photon absorption and light emission. Their fluorescence behavior discloses an unusual increasing blue shift with increasing solvent polarity, which, in parallel, is beneficial for enhanced detection in biological media.
Carlos Benitez‐Martin, Jose M. Marin‐Beloqui, Juan T. López Navarrete, Juan Casado, Francisco Najera, Ezequiel Perez‐Inestrosa   +5 more
wiley   +1 more source

Biological sex affects human islet gene expression and mitochondrial function in type 2 diabetes.

Endocrinology
Chen SY, Cen HH, Chao CF, Pepper AR, Johnson JD, Rideout EJ.   +5 more
europepmc   +1 more source

TRIP13 alters mitochondrial function and promotes bortezomib resistance in multiple myeloma. [PDF]

Sci Rep
Chen Y, Liu Y, Wang Y, Qi D, Peng C, Huang S, Guo J, Xu Z, Gu Y.   +8 more
europepmc   +1 more source