Results 61 to 70 of about 662,543 (166)

Excess Branched-Chain Amino Acids Suppress Mitochondrial Function and Biogenic Signaling but Not Mitochondrial Dynamics in a Myotube Model of Skeletal Muscle Insulin Resistance

Metabolites
Branched-chain amino acids (BCAA) are correlated with severity of insulin resistance, which may partially result from mitochondrial dysfunction. Mitochondrial dysfunction is also common during insulin resistance and is regulated in part by altered ...
Lindsey R. VanDerStad, Emily C. Wyatt, Roger A. Vaughan   +2 more
doaj   +1 more source

Insulin action in the brain regulates mitochondrial stress responses and reduces diet-induced weight gain

Molecular Metabolism, 2019
Objective: Insulin action in the brain controls metabolism and brain function, which is linked to proper mitochondrial function. Conversely, brain insulin resistance associates with mitochondrial stress and metabolic and neurodegenerative diseases.
Kristina Wardelmann, Sabine Blümel, Michaela Rath, Eugenia Alfine, Chantal Chudoba, Mareike Schell, Weikang Cai, Robert Hauffe, Kathrin Warnke, Tanina Flore, Katrin Ritter, Jürgen Weiß, C. Ronald Kahn, André Kleinridders   +13 more
doaj   +1 more source

Diet impact on Mitochondrial Bioenergetics and Dynamics

Frontiers in Physiology, 2015
Diet induced obesity is associated with impaired mitochondrial function and dynamic behavior. Mitochondria are highly dynamic organelles and the balance in fusion/fission is strictly associated with their bioenergetics.
Rosalba ePutti, Raffaella eSica, Vincenzo eMigliaccio, Lillà eLionetti   +3 more
doaj   +1 more source

522 CNS complications in women living with HIV: The role of mitochondrial function

Journal of Clinical and Translational Science
Objectives/Goals: As life expectancy increases in people with HIV, neurocognitive impairment is becoming more common, and women with HIV (WWH) are disproportionately impacted.
Hannah Stadtler, Isabel Santiuste, Leah Rubin, Gretchen Neigh   +3 more
doaj   +1 more source

Mitochondrial Dysfunction in Neurodegenerative Diseases

MedComm
Mitochondria are indispensable for the normal physiological activities and metabolism of living organisms. The proper function of mitochondria in the brain is crucial for maintaining the normal brain function with high energy demands.
Chongyang Chen, Yujie Zhao, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Xifei Yang, Ming Lu, Gong‐Ping Liu   +10 more
doaj   +1 more source

METTL3-dependent m6A modification of GHR mRNA regulates mitochondrial function through mitochondrial biogenesis during myoblast differentiation

Poultry Science
N6-methyl-adenosine (m6A) methylation has recently been shown to play a critical role in muscle development. We recently revealed that local GHR knockdown impairs mitochondrial function by inhibiting mitochondrial biogenesis, thereby repressing myoblast ...
Changbin Zhao, Bowen Hu, Zhijun Wang, Ze Zhang, Wen Luo, Hongmei Li, Xiquan Zhang   +6 more
doaj   +1 more source

Fusion activators enhance mitochondrial function

Mitochondrial Communications, 2023
William M. Rosencrans, David C. Chan
doaj   +1 more source

CD28 enhances mitochondrial function [PDF]

Nature Immunology, 2017
openaire   +2 more sources

Potassium ion homeostasis modulates mitochondrial function. [PDF]

J Cell Biol
Waite AJ, Rao B, Schinski E, Thayer NH, Hotz M, Lefebvre AEYT, Sandoval C, Gottschling DE.   +7 more
europepmc   +1 more source

E-cigarette exposure impairs skeletal muscle mitochondrial function in male mice. [PDF]

Physiol Rep
Mazirka P, Choi J, Alvarez S, Jahuey P, O'Malley KA, Robinson ST, Scali ST, Ryan TE, Berceli SA, Kim K.   +9 more
europepmc   +1 more source