Results 1 to 10 of about 549,014 (338)

Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome

open access: yes, 2019
Mitochondrial DNA (mtDNA) heteroplasmy (intra-individual variation) varies among different human tissues and increases with age, suggesting that the majority of mtDNA heteroplasmies are acquired, rather than inherited.
Eis-Hübinger, A.   +6 more
core   +1 more source

Fluorescent Visualization of In Vitro Mitochondrial DNA Transcription [PDF]

open access: yes, 2019
Mitochondria are important organelles within eukaryotic cells especially for their role in metabolism and ATP production by the oxidative phosphorylation (OXPHOS) pathway. In human cells there are approximately 80 protein subunits that make up the OXPHOS
Bruce, Kelsey
core   +1 more source

The complete mitochondrial genome of Gadus chalcogramma and phylogenetic analysis

open access: yesMitochondrial DNA. Part B. Resources, 2018
Here, we report the complete mitochondrial genome sequence of Alaska Pollock, Gadus chalcogramma. The genome sequence was obtained via long PCR reactions using universal primer sets for the fish mitochondrial genome.
Han-Kyeol Sim   +2 more
doaj   +1 more source

Survey of Human Mitochondrial Diseases Using New Genomic/Proteomic Tools [PDF]

open access: yes, 2001
BACKGROUND. We have constructed Bayesian prior-based, amino-acid sequence profiles for the complete yeast mitochondrial proteome and used them to develop methods for identifying and characterizing the context of protein mutations that give rise to human ...
Mohr, Scott C.   +2 more
core   +2 more sources

Drawing mitochondrial genomes with circularMT

open access: yesBioinformatics
Abstract Summary Mitochondrial DNA sequences are used extensively in phylogeographic and phylogenetic studies for a wide range of organisms. With the advent of low-cost, high-throughput “next generation” DNA sequencing, and user-friendly bioinformatics pipelines for generating and annotating whole ...
Simon J Goodman, Ian M Carr
openaire   +2 more sources

Transfer of mitochondrial DNA into the nuclear genome during induced DNA breaks

open access: yesNature Communications
Mitochondria serve as the cellular powerhouse, and their distinct DNA makes them a prospective target for gene editing to treat genetic disorders. However, the impact of genome editing on mitochondrial DNA (mtDNA) stability remains a mystery.
Jinchun Wu   +12 more
doaj   +1 more source

Mitochondrial Genome and Plant Taxonomy

open access: yes, 2013
The lability in size, structure, and sequence content of mitochondrial genome (mtDNA) across plant species has sharply limited its use in taxonomic studies. However, due to the new opportunities offered by the availability of complete mtDNA sequence in plant species and the subsequent development of universal primers, the number of mtDNA-based ...
openaire   +2 more sources

Translocation of a 190-kb mitochondrial fragment into rice chromosome 12 followed by the integration of four retrotransposons

open access: yesInternational Journal of Biological Sciences, 2005
A 190-kb mitochondrial DNA sequence interrupted by seven foreign DNA segments was identified in rice chromosome 12. This fragment is the largest mitochondrial fragment translocated into the rice nuclear genome.
doaj  

Complete mitochondrial genome of Houttuynia cordata sheds light on the evolution of complex structural features in early angiosperms

open access: yesBMC Plant Biology
Background Houttuynia cordata is a well-known medicinal and edible plant with important economic value. It belongs to the magnoliid clade, a basal lineage of angiosperms.
Yahui Huang   +8 more
doaj   +1 more source

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