Results 1 to 10 of about 306,673 (119)

Mitochondrial Fostering: The Mitochondrial Genome May Play a Role in Plant Orphan Gene Evolution

Frontiers in Plant Science, 2020
Plant mitochondrial genomes exhibit unique evolutionary patterns. They have a high rearrangement but low mutation rate, and a large size. Based on massive mitochondrial DNA transfers to the nucleus as well as the mitochondrial unique evolutionary traits,
Seth O’Conner, Ling Li
doaj   +3 more sources

Structural characteristics of the melon mitochondria genome

Vegetable Research, 2022
The mitochondrial genome can provide important genetic information of melon. We reported the mitochondrial genome sequence of melon in a previous study, the structural characteristics of the melon mitochondrial genome were further analyzed in the present
Haonan Cui, Zhuo Ding, Qianglong Zhu, Peng Gao   +3 more
doaj   +1 more source

Treatable inherited metabolic disorders causing intellectual disability: 2021 review and digital app

Orphanet Journal of Rare Diseases, 2021
Background The Treatable ID App was created in 2012 as digital tool to improve early recognition and intervention for treatable inherited metabolic disorders (IMDs) presenting with global developmental delay and intellectual disability (collectively ...
Eva M. M. Hoytema van Konijnenburg, Saskia B. Wortmann, Marina J. Koelewijn, Laura A. Tseng, Roderick Houben, Sylvia Stöckler-Ipsiroglu, Carlos R. Ferreira, Clara D. M. van Karnebeek   +7 more
doaj   +1 more source

Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging

Genome Biology, 2020
Background Acquired human mitochondrial genome (mtDNA) deletions are symptoms and drivers of focal mitochondrial respiratory deficiency, a pathological hallmark of aging and late-onset mitochondrial disease.
Scott A. Lujan, Matthew J. Longley, Margaret H. Humble, Christopher A. Lavender, Adam Burkholder, Emma L. Blakely, Charlotte L. Alston, Grainne S. Gorman, Doug M. Turnbull, Robert McFarland, Robert W. Taylor, Thomas A. Kunkel, William C. Copeland   +12 more
doaj   +1 more source

Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability

EMBO Molecular Medicine, 2023
Topoisomerase 3α (TOP3A) is an enzyme that removes torsional strain and interlinks between DNA molecules. TOP3A localises to both the nucleus and mitochondria, with the two isoforms playing specialised roles in DNA recombination and replication ...
Direnis Erdinc, Alejandro Rodríguez‐Luis, Mahmoud R Fassad, Sarah Mackenzie, Christopher M Watson, Sebastian Valenzuela, Xie Xie, Katja E Menger, Kate Sergeant, Kate Craig, Sila Hopton, Gavin Falkous, Genomics England Research Consortium, Joanna Poulton, Hector Garcia‐Moreno, Paola Giunti, Carlos A de Moura Aschoff, Jonas A Morales Saute, Amelia J Kirby, Camilo Toro, Lynne Wolfe, Danica Novacic, Lior Greenbaum, Aviva Eliyahu, Ortal Barel, Yair Anikster, Robert McFarland, Gráinne S Gorman, Andrew M Schaefer, Claes M Gustafsson, Robert W Taylor, Maria Falkenberg, Thomas J Nicholls   +32 more
doaj   +1 more source

The inflated mitochondrial genomes of siphonous green algae reflect processes driving expansion of noncoding DNA and proliferation of introns [PDF]

PeerJ, 2020
Within the siphonous green algal order Bryopsidales, the size and gene arrangement of chloroplast genomes has been examined extensively, while mitochondrial genomes have been mostly overlooked.
Sonja I. Repetti, Christopher J. Jackson, Louise M. Judd, Ryan R. Wick, Kathryn E. Holt, Heroen Verbruggen   +5 more
doaj   +2 more sources

Characterization of the complete mitochondrial genome of Dioszegia changbaiensis (Tremellales: Bulleribasidiaceae) with phylogenetic implications

Mitochondrial DNA. Part B. Resources, 2021
In this study, the complete mitochondrial genome of Dioszegia changbaiensis we sequenced and assembled by the next-generation sequencing. The complete mitochondrial genome of Dioszegia changbaiensis contained 22 protein-coding genes (PCG), two ribosomal ...
Maoling Tan, Qiangfeng Wang
doaj   +1 more source

Mitochondrial Non-Coding RNAs Are Potential Mediators of Mitochondrial Homeostasis

Biomolecules, 2022
Mitochondria are the energy production center in cells, which regulate aerobic metabolism, calcium balance, gene expression and cell death. Their homeostasis is crucial for cell viability.
Weihan Sun, Yijian Lu, Heng Zhang, Jun Zhang, Xinyu Fang, Jianxun Wang, Mengyang Li   +6 more
doaj   +1 more source

Characterization of the complete mitochondrial genome of biocontrol yeast Sporobolomyces sp. (Sporidiobolales: Sporidiobolaceae) with phylogenetic analysis

Mitochondrial DNA. Part B. Resources, 2020
In this study, we obtained the complete mitochondrial genome of Sporobolomyces sp. using next-generation sequencing. The complete mitochondrial genome of Sporobolomyces sp.
Jingwei Huang, Huijuan Qu, Xueshan Shen
doaj   +1 more source

Characterization of the complete mitochondrial genome of Sterigmatomyces hyphaenes (Agaricostilbales: Agaricostilbaceae) and implications for its phylogeny

Mitochondrial DNA. Part B. Resources, 2020
In this study, the complete mitochondrial genome of Sterigmatomyces hyphaenes was sequenced by the next-generation sequencing. The complete mitochondrial genome of S. hyphaenes contained 17 protein-coding genes (PCG), 2 ribosomal RNA (rRNA) genes, and 23
Maoling Tan, Qiangfeng Wang
doaj   +1 more source