Results 1 to 10 of about 311,260 (298)

The complete mitochondrial genome of Cervus canadensis (Erxleben, 1777), as a model species of Chronic Wasting Disease (CWD) [PDF]

Mitochondrial DNA. Part B. Resources, 2020
Cervus canadensis (Erxleben, 1777) has been used as a model species of Chronic Wasting Disease (CWD). We completed the mitochondrial genome of C. canadensis, susceptible to the CWD.
Hyo-Jin Kim, Ji-Yong Hwang, Kyung-Je Park, Hoo-Chang Park, Hae-Eun Kang, Jongsun Park, Hyun-Joo Sohn   +6 more
doaj   +2 more sources

Structural characteristics of the melon mitochondria genome

Vegetable Research, 2022
The mitochondrial genome can provide important genetic information of melon. We reported the mitochondrial genome sequence of melon in a previous study, the structural characteristics of the melon mitochondrial genome were further analyzed in the present
Haonan Cui, Zhuo Ding, Qianglong Zhu, Peng Gao   +3 more
doaj   +1 more source

Lophotrochozoan mitochondrial genomes [PDF]

Integrative and Comparative Biology, 2006
Progress in both molecular techniques and phylogenetic methods has challenged many of the interpretations of traditional taxonomy. One example is in the recognition of the animal superphylum Lophotrochozoa (annelids, mollusks, echiurans, platyhelminthes, brachiopods, and other phyla), although the relationships within this group and the inclusion of ...
Valles, Yvonne, Boore, Jeffrey L.
openaire   +3 more sources

Treatable inherited metabolic disorders causing intellectual disability: 2021 review and digital app

Orphanet Journal of Rare Diseases, 2021
Background The Treatable ID App was created in 2012 as digital tool to improve early recognition and intervention for treatable inherited metabolic disorders (IMDs) presenting with global developmental delay and intellectual disability (collectively ...
Eva M. M. Hoytema van Konijnenburg, Saskia B. Wortmann, Marina J. Koelewijn, Laura A. Tseng, Roderick Houben, Sylvia Stöckler-Ipsiroglu, Carlos R. Ferreira, Clara D. M. van Karnebeek   +7 more
doaj   +1 more source

Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging

Genome Biology, 2020
Background Acquired human mitochondrial genome (mtDNA) deletions are symptoms and drivers of focal mitochondrial respiratory deficiency, a pathological hallmark of aging and late-onset mitochondrial disease.
Scott A. Lujan, Matthew J. Longley, Margaret H. Humble, Christopher A. Lavender, Adam Burkholder, Emma L. Blakely, Charlotte L. Alston, Grainne S. Gorman, Doug M. Turnbull, Robert McFarland, Robert W. Taylor, Thomas A. Kunkel, William C. Copeland   +12 more
doaj   +1 more source

Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability

EMBO Molecular Medicine, 2023
Topoisomerase 3α (TOP3A) is an enzyme that removes torsional strain and interlinks between DNA molecules. TOP3A localises to both the nucleus and mitochondria, with the two isoforms playing specialised roles in DNA recombination and replication ...
Direnis Erdinc, Alejandro Rodríguez‐Luis, Mahmoud R Fassad, Sarah Mackenzie, Christopher M Watson, Sebastian Valenzuela, Xie Xie, Katja E Menger, Kate Sergeant, Kate Craig, Sila Hopton, Gavin Falkous, Genomics England Research Consortium, Joanna Poulton, Hector Garcia‐Moreno, Paola Giunti, Carlos A de Moura Aschoff, Jonas A Morales Saute, Amelia J Kirby, Camilo Toro, Lynne Wolfe, Danica Novacic, Lior Greenbaum, Aviva Eliyahu, Ortal Barel, Yair Anikster, Robert McFarland, Gráinne S Gorman, Andrew M Schaefer, Claes M Gustafsson, Robert W Taylor, Maria Falkenberg, Thomas J Nicholls   +32 more
doaj   +1 more source

Mitochondrial helicases and mitochondrial genome maintenance [PDF]

Mechanisms of Ageing and Development, 2010
Helicases are essential enzymes that utilize the energy of nucleotide hydrolysis to drive unwinding of nucleic acid duplexes. Helicases play roles in all aspects of DNA metabolism including DNA repair, DNA replication and transcription. The subcellular locations and functions of several helicases have been studied in detail; however, the roles of ...
de Souza-Pinto, Nadja C, Aamann, Maria Diget, Kulikowicz, Tomasz, Stevnsner, Tinna V., Bohr, Vilhelm A   +4 more
openaire   +4 more sources

Characterization of the complete mitochondrial genome of Dioszegia changbaiensis (Tremellales: Bulleribasidiaceae) with phylogenetic implications

Mitochondrial DNA. Part B. Resources, 2021
In this study, the complete mitochondrial genome of Dioszegia changbaiensis we sequenced and assembled by the next-generation sequencing. The complete mitochondrial genome of Dioszegia changbaiensis contained 22 protein-coding genes (PCG), two ribosomal ...
Maoling Tan, Qiangfeng Wang
doaj   +1 more source

The inflated mitochondrial genomes of siphonous green algae reflect processes driving expansion of noncoding DNA and proliferation of introns [PDF]

PeerJ, 2020
Within the siphonous green algal order Bryopsidales, the size and gene arrangement of chloroplast genomes has been examined extensively, while mitochondrial genomes have been mostly overlooked.
Sonja I. Repetti, Christopher J. Jackson, Louise M. Judd, Ryan R. Wick, Kathryn E. Holt, Heroen Verbruggen   +5 more
doaj   +2 more sources

Mitochondrial Non-Coding RNAs Are Potential Mediators of Mitochondrial Homeostasis

Biomolecules, 2022
Mitochondria are the energy production center in cells, which regulate aerobic metabolism, calcium balance, gene expression and cell death. Their homeostasis is crucial for cell viability.
Weihan Sun, Yijian Lu, Heng Zhang, Jun Zhang, Xinyu Fang, Jianxun Wang, Mengyang Li   +6 more
doaj   +1 more source