Results 1 to 10 of about 1,628,733 (342)

De novo assembly of the complete mitochondrial genome of sweet potato (Ipomoea batatas [L.] Lam) revealed the existence of homologous conformations generated by the repeat-mediated recombination

BMC Plant Biology, 2022
Sweet potato (Ipomoea batatas [L.] Lam) is an important food crop, an excellent fodder crop, and a new type of industrial raw material crop. The lack of genomic resources could affect the process of industrialization of sweet potato. Few detailed reports
Zhijian Yang, Yang Ni, Zebin Lin, Liubin Yang, Guotai Chen, Nuerla Nijiati, Yunzhuo Hu, Xuanyang Chen   +7 more
doaj   +2 more sources

MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads

bioRxiv, 2023
Background  PacBio high fidelity (HiFi) sequencing reads are both long (15–20 kb) and highly accurate (> Q20). Because of these properties, they have revolutionised genome assembly leading to more accurate and contiguous genomes.
Marcela Uliano-Silva, João Gabriel R. N. Ferreira, Ksenia Krasheninnikova, G. Formenti, Linelle Abueg, J. Torrance, Eugene W. Myers, R. Durbin, Mark Blaxter, Shane A. McCarthy   +9 more
semanticscholar   +1 more source

The complete mitochondrial genome of okra (Abelmoschus esculentus): using nanopore long reads to investigate gene transfer from chloroplast genomes and rearrangements of mitochondrial DNA molecules

BMC Genomics, 2022
Okra (Abelmoschus esculentus L. Moench) is an economically important crop and is known for its slimy juice, which has significant scientific research value. The A.
Jihan Li, Jingling Li, Yubo Ma, Lu Kou, Juanjuan Wei, Weixing Wang   +5 more
semanticscholar   +1 more source

Structural characteristics of the melon mitochondria genome

Vegetable Research, 2022
The mitochondrial genome can provide important genetic information of melon. We reported the mitochondrial genome sequence of melon in a previous study, the structural characteristics of the melon mitochondrial genome were further analyzed in the present
Haonan Cui, Zhuo Ding, Qianglong Zhu, Peng Gao   +3 more
doaj   +1 more source

Treatable inherited metabolic disorders causing intellectual disability: 2021 review and digital app

Orphanet Journal of Rare Diseases, 2021
Background The Treatable ID App was created in 2012 as digital tool to improve early recognition and intervention for treatable inherited metabolic disorders (IMDs) presenting with global developmental delay and intellectual disability (collectively ...
Eva M. M. Hoytema van Konijnenburg, Saskia B. Wortmann, Marina J. Koelewijn, Laura A. Tseng, Roderick Houben, Sylvia Stöckler-Ipsiroglu, Carlos R. Ferreira, Clara D. M. van Karnebeek   +7 more
doaj   +1 more source

Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging

Genome Biology, 2020
Background Acquired human mitochondrial genome (mtDNA) deletions are symptoms and drivers of focal mitochondrial respiratory deficiency, a pathological hallmark of aging and late-onset mitochondrial disease.
Scott A. Lujan, Matthew J. Longley, Margaret H. Humble, Christopher A. Lavender, Adam Burkholder, Emma L. Blakely, Charlotte L. Alston, Grainne S. Gorman, Doug M. Turnbull, Robert McFarland, Robert W. Taylor, Thomas A. Kunkel, William C. Copeland   +12 more
doaj   +1 more source

Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability

EMBO Molecular Medicine, 2023
Topoisomerase 3α (TOP3A) is an enzyme that removes torsional strain and interlinks between DNA molecules. TOP3A localises to both the nucleus and mitochondria, with the two isoforms playing specialised roles in DNA recombination and replication ...
Direnis Erdinc, Alejandro Rodríguez‐Luis, Mahmoud R Fassad, Sarah Mackenzie, Christopher M Watson, Sebastian Valenzuela, Xie Xie, Katja E Menger, Kate Sergeant, Kate Craig, Sila Hopton, Gavin Falkous, Genomics England Research Consortium, Joanna Poulton, Hector Garcia‐Moreno, Paola Giunti, Carlos A de Moura Aschoff, Jonas A Morales Saute, Amelia J Kirby, Camilo Toro, Lynne Wolfe, Danica Novacic, Lior Greenbaum, Aviva Eliyahu, Ortal Barel, Yair Anikster, Robert McFarland, Gráinne S Gorman, Andrew M Schaefer, Claes M Gustafsson, Robert W Taylor, Maria Falkenberg, Thomas J Nicholls   +32 more
doaj   +1 more source

The inflated mitochondrial genomes of siphonous green algae reflect processes driving expansion of noncoding DNA and proliferation of introns [PDF]

PeerJ, 2020
Within the siphonous green algal order Bryopsidales, the size and gene arrangement of chloroplast genomes has been examined extensively, while mitochondrial genomes have been mostly overlooked.
Sonja I. Repetti, Christopher J. Jackson, Louise M. Judd, Ryan R. Wick, Kathryn E. Holt, Heroen Verbruggen   +5 more
doaj   +2 more sources

Characterization of the complete mitochondrial genome of Dioszegia changbaiensis (Tremellales: Bulleribasidiaceae) with phylogenetic implications

Mitochondrial DNA. Part B. Resources, 2021
In this study, the complete mitochondrial genome of Dioszegia changbaiensis we sequenced and assembled by the next-generation sequencing. The complete mitochondrial genome of Dioszegia changbaiensis contained 22 protein-coding genes (PCG), two ribosomal ...
Maoling Tan, Qiangfeng Wang
doaj   +1 more source

Mitochondrial Non-Coding RNAs Are Potential Mediators of Mitochondrial Homeostasis

Biomolecules, 2022
Mitochondria are the energy production center in cells, which regulate aerobic metabolism, calcium balance, gene expression and cell death. Their homeostasis is crucial for cell viability.
Weihan Sun, Yijian Lu, Heng Zhang, Jun Zhang, Xinyu Fang, Jianxun Wang, Mengyang Li   +6 more
doaj   +1 more source