Results 101 to 110 of about 328,957 (317)

The bipartite mitochondrial genome of Ruizia karukerae (Rhigonematomorpha, Nematoda)

Scientific Reports, 2018
Mitochondrial genes and whole mitochondrial genome sequences are widely used as molecular markers in studying population genetics and resolving both deep and shallow nodes in phylogenetics.
Taeho Kim, Elizabeth Kern, Chungoo Park, Steven A. Nadler, Yeon Jae Bae, Joong-Ki Park   +5 more
doaj   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Early diagnosis of Pearson syndrome in neonatal intensive care following rapid mitochondrial genome sequencing in tandem with exome sequencing

, 2019
Rapid genomic testing is a valuable new diagnostic tool for acutely unwell infants, however exome sequencing does not deliver clinical-grade mitochondrial genome sequencing and may fail to diagnose mitochondrial disorders caused by mitochondrial DNA ...
Lunke, Sebastian, Eggers, Stefanie, Zornitza Stark, Tiong Y. Tan, Akesson, Lauren S, John Christodoulou, Christodoulou, John, David R. Thorburn, Sebastian Lunke, Matthew F. Hunter, Richmond, Christopher M, Christopher M. Richmond, Love, Clare J, Belinda Chong, Tan, Tiong Y, Thorburn, David R, Clare J. Love, Stefanie Eggers, Chong, Belinda, Hunter, Matthew F, Brown, Natasha J, Krzesinski, Emma I, Emma I. Krzesinski, Lauren S. Akesson, Natasha J. Brown, Stark, Zornitza   +25 more
core   +1 more source

Genome Digging: Insight into the Mitochondrial Genome of Homo

PLoS ONE, 2010
A fraction of the Neanderthal mitochondrial genome sequence has a similarity with a 5,839-bp nuclear DNA sequence of mitochondrial origin (numt) on the human chromosome 1. This fact has never been interpreted. Although this phenomenon may be attributed to contamination and mosaic assembly of Neanderthal mtDNA from short sequencing reads, we explain the
Igor V Ovchinnikov, Olga I Kholina
openaire   +4 more sources

The complete mitochondrial genome of the Chilotilapia rhoadesii

Mitochondrial DNA. Part B. Resources, 2017
In this study, we firstly reported the complete mitochondrial genome of Chilotilapia rhoadesii. The whole mitochondrial genome is 16,580 bp in length, including 2 ribosomal RNA genes, 22 transfer RNA genes and 13 protein-coding genes.
Xiangru Wen, Cailin Wang, Man Li, Haiyan Wang, Xu Zhou   +4 more
doaj   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

Meles leucurus mitochondrial genome

, 2022
We report the complete mitochondrial genome sequence of Asian badger, Meles leucurus. The complete mitochondrial genome is 16,404 bp in length and contains 13 protein coding genes, 22 transfer RNA, 2 ribosomal RNA and 1 control region.
KIM, H (via Mendeley Data)
core   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Mitochondrial genome variability: the effect on cellular functional activity

, 2018
Aleksandrina S Volobueva,1 Alexandra A Melnichenko,2 Andrey V Grechko,3 Alexander N Orekhov2,4 1Laboratory of Gene Therapy, Biocad Biotechnology Company, Saint-Petersburg, Strelnya, Russia; 2Laboratory of Angiopathology, Institute of General Pathology ...
Melnichenko AA, Volobueva AS, Grechko AV, Orekhov AN   +3 more
core  

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

Advanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu, Edgar E. Perez Carbajal, Yih‐Chii Hwang, Sahil A. Mapkar, Benjamin W. Gilman, Sarah A. Bliss, Lam B. Tran, Kalgi T. Mehta, Jacob O. Banyasz, Ming Yu, Reynold R. Liu, Matthew N. Ly, Christapher S. Morrissey, Michael N. Wosczyna   +13 more
wiley   +1 more source