Results 111 to 120 of about 540,064 (337)

The mitochondrial genome of Cofana yasumatsui (Hemiptera: Cicadellidae: Cicadellinae) [PDF]

, 2020
Li-Kun Zhong, Maofa Yang, Xiaofei Yu
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A genomic approach to the study of Tribolium castaneum genetics, development & evolution [PDF]

, 2004
During the last decade, Tribolium castaneum has become the insect of choice for comparative genetics and developmental studies outside of drosophilids. Until recently, most molecular studies have focused on the comparative analysis of early development ...
Savard, Joël
core  

Genome Digging: Insight into the Mitochondrial Genome of Homo

PLoS ONE, 2010
A fraction of the Neanderthal mitochondrial genome sequence has a similarity with a 5,839-bp nuclear DNA sequence of mitochondrial origin (numt) on the human chromosome 1. This fact has never been interpreted. Although this phenomenon may be attributed to contamination and mosaic assembly of Neanderthal mtDNA from short sequencing reads, we explain the
Igor V Ovchinnikov, Olga I Kholina
openaire   +4 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Sequencing and phylogenetic analysis of the complete mitochondrial genome of the Eurasian Harvest Mouse (Micromys minutus) Pallas 1771 from China

Mitochondrial DNA. Part B. Resources
This study aimed to examine the complete mitochondrial genome sequence of the Eurasian Harvest Mouse (Micromys minutus) through polymerase chain reaction. The mitochondrial genome of M.
Hong-Yan Wang, Yu-Qi Wu, Zhi-Hui Zhang, Zhu Liu   +3 more
doaj   +1 more source

The complete mitochondrial genome of Hericium coralloides (Hericiaceae, Basidiomycota)

Mitochondrial DNA. Part B. Resources, 2017
In this study, the complete mitochondrial genome of the medicinal mushroom Hericium coralloides (Hericiaceae, Basidiomycota) was sequenced. This mitochondrial genome is 72,961 bp in length and consisted of 14 protein-coding genes, 21 hypothetical open ...
Caixia Zhang, Changshan Li, Weixing Ye, Manjun Yang   +3 more
doaj   +1 more source

The validity of the subspecies, Teinopalpus aureus wuyiensis Lee, from complete mitochondrial genome [PDF]

, 2021
Zou Wu, Chao-Bin Huang, Lu Wang, Jiang Meng-na, Shanyi Zhou, Jiangtao Zhang, Juping Zeng   +6 more
openalex   +1 more source

The Mechanisms of Codon Reassignments in Mitochondrial Genetic Codes [PDF]

, 2007
Many cases of non-standard genetic codes are known in mitochondrial genomes. We carry out analysis of phylogeny and codon usage of organisms for which the complete mitochondrial genome is available, and we determine the most likely mechanism for codon ...
A Reyes, A Schneider, AM Nedelcu, AM Simpson, AP Sibler, BF Lang, C Gissi, CA Lozupone, CE Bullerwell, D Urbina, DH Ardell, DV Lavrov, DW Schultz, DW Schultz, E Seif, E Talla, EM Denovan-Wright, FHC Crick, G Burger, G Burger, G Burger, H Asahara, HS Kim, J Castrasena, J Matsugi, J Swire, JD Alfonzo, JL Blanchard, JL Boore, K Hancock, K Tomita, Knight, Knight, M Ehara, M Ehara, M Kimura, M Nohara, M Turmel, MAS Santos, MAS Santos, ME Saks, MJ Laforest, MJ Telford, MV Sanchez Puerta, N Spruyt, NJ Savill, Paul G. Higgs, PG Higgs, PG Higgs, PJ Keeling, PS Lovett, R Giegé, R Koszul, RC Morris, S Kerscher, S Matsuyama, S Osawa, S Osawa, S Osawa, S Sengupta, S Yokobori, SE Massey, SG Andersson, SG Andersson, SJ Freeland, Supratim Sengupta, T Muramatsu, Tomita, Tomita, U Kück, Xiaoguang Yang, Y Hayashi-Ishimaru, Y Hayashi-Ishimaru, Y Inagaki, Y Kuchino   +74 more
core   +4 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source