Results 231 to 240 of about 1,628,733 (342)

Dynamic evolution of plant mitochondrial genomes: Mobile genes and introns and highly variable mutation rates

, 2000
Jeffrey D. Palmer, Keith L. Adams, Yangrae Cho, Christopher L. Parkinson, Yin‐Long Qiu, Keming Song   +5 more
openalex   +1 more source

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

Characterization of the complete mitochondrial genome of Monticola rufiventris and phylogenetic implications. [PDF]

Sci Rep
Hou R, Zhang Q, Duan M, Tang S, Liu S, Jiang D, Du C, Yang X.   +7 more
europepmc   +1 more source

Paracrine Orchestration of Tumor Microenvironment Remodeling Induced by GLO1 Potentiates Lymph Node Metastasis in Breast Cancer

Advanced Science, EarlyView.
Single‐cell RNA sequencing of lymph node (LN) samples is performed, and a comprehensive landscape of the entire ecosystem is generated. Paracrine orchestration of TME remodeling induced by GLO1 potentiates LN metastasis in breast cancer. This study offers novel perspectives on the microenvironment remodeling of breast cancer LN metastases, suggesting ...
Jindong Xie, Wenjian Liu, Xinpei Deng, Huan Wang, Xueqi Ou, Xin An, Min‐Yi Situ, Anli Yang, Chuan Peng, Rongfang He, Yi Xie, Hailin Tang, Yuman Chen, Jie‐Ying Liang, Ruonan Shao, Weikai Xiao, Shaoquan Zheng   +16 more
wiley   +1 more source

Correction: Mitochondrial genome assembly and comparative analysis of decaploid <i>Camellia hainanica</i>. [PDF]

Front Plant Sci
Zhang S, Zhang Y, Luo S, Gao J, Hu H, Liu J, Wu W, Wang J, Huang X, Lai H, Huang D.   +10 more
europepmc   +1 more source

NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β‐TrCP1/FBXO5 Axis

Advanced Science, EarlyView.
Host E3 ligase FBXO5 as a key regulator that promotes K48‐linked ubiquitination and proteasomal degradation of SARS‐CoV‐2 NSP7, thereby suppressing viral replication. NSP7 ubiquitination is co‐regulated by β‐TrCP1 and TAF1. Small molecule BC24877 disrupts β‐TrCP1‐mediated degradation of FBXO5, stabilizing FBXO5 and enhancing NSP7 clearance ...
Yao Tong, Travis B. Lear, Ferhan Tuncer, John J. Villandre, Áine N. Boudreau, Bo Lin, Irene Alfaras, Jason R. Kennerdell, Daniel P. Camarco, Mads B. Larsen, Yun Hua, Yanwen Chen, Meigin E. Chandler, Ricardo Pineda, Simon M. Barratt‐Boyes, John W. Evankovich, Toren Finkel, Yuan Liu, Bill B. Chen   +18 more
wiley   +1 more source

The complete mitochondrial genome of sand anemone, <i>Paracondylactis hertwigi</i> (Wassilieff, 1908). [PDF]

Mitochondrial DNA B Resour
Lee SJ, Lee SH, Yu HJ, Cho IY, Hwang SJ.
europepmc   +1 more source

The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor‐Intrinsic PD‐1/c‐MET Signaling in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han, Hanlin Yin, Taochen He, Junyi He, Zhenlai Jiang, Qiangda Chen, Zhihang Xu, Yuqi Xie, Yaolin Xu, Haibo Wang, Wenquan Wang, Wenchuan Wu, Yun Jin, Wenhui Lou, Jun Yu, Ning Pu, Liang Liu   +16 more
wiley   +1 more source

Assembly and comparative analysis of the complete mitochondrial genome of the spice plant Cinnamomum longepaniculatum. [PDF]

BMC Plant Biol
Fan Y, Tan L, Feng R, Zhao X, Xu X.
europepmc   +1 more source

The Complete Sequence of the Mitochondrial Genome of the Crustacean Penaeus monodon: Are Malacostracan Crustaceans More Closely Related to Insects than to Branchiopods?

, 2000
Kate J. Wilson, Valma Cahill, E. Ballment, John Benzie   +3 more
openalex   +1 more source