Results 231 to 240 of about 543,214 (334)

Genome-scale transfer of mitochondrial DNA from legume hosts to the holoparasite Lophophytum mirabile (Balanophoraceae)

, 2018
M. Virginia Sanchez‐Puerta, Alejandro Edera, Carolina L. Gandini, Anna V. Williams, Katharine A. Howell, Paul Nevill, Ian Small   +6 more
openalex   +2 more sources

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Inhibition of Mitochondrial Genome-Encoded Mitomir-3 Contributes to Zeb1 Mediated Gpx4 Downregulation and Pro-Ferroptotic Lipid Metabolism to Induce Ferroptosis in Breast Cancer Cells

Amoolya Kandettu, Joydeep Ghosal, Jesline Shaji Tharayil, Raviprasad Kuthethur, Sandeep Mallya, Rekha Koravadi Narasimhamurthy, Kamalesh Dattaram Mumbrekar, Yashwanth Subbannayya, Na An, Raghu Radhakrishnan, Shama Prasada Kabekkodu, Sanjiban Chakrabarty   +11 more
openalex   +1 more source

The first complete mitochondrial genome sequence of the mud crab Macrophthalmus japonicus (arthropoda, decapoda, macrophthalmidae) [PDF]

, 2018
Yeong-Jun Park, Chang Eon Park, Byung Kwon Jung, Minkyu Park, Jerald Conrad Ibal, Sang-Jun Kim, Seok Hyun Lee, Hyun Sook Ko, Jae‐Ho Shin   +8 more
openalex   +1 more source

Iron Overload Mediates the Differential Cell Fate of Astrocytes from Neurons and Its Regulatory Mechanisms in Ischemic Stroke

Advanced Science, EarlyView.
Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo, Yue Wang, Yong Ni, Bin Bo, Jinzhi He, Yongming Zhu, Aiping Qin, Xianyong Zhou, Huaping Du, Yuan Liu, Tianyao Wang, Yudu Li, Yibo Zhao, Zengai Chen, Zhipei Liang, Yao Li, Yuan Xu, Huiling Zhang   +17 more
wiley   +1 more source

The complete mitochondrial genome of <i>Ischiodon scutellaris</i> (Diptera: Syrphidae: Syrphinae). [PDF]

Mitochondrial DNA B Resour
Zhou J, Li Y, Cai X, Li F, Xiao HP, Huang GH.   +5 more
europepmc   +1 more source

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

Advanced Science, EarlyView.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu, Bixiao Liu, Yu Yang, Tao Meng, Yuanyuan Chang, Yao Peng, Jia Guo, Zhuqing Wang, Hongqian Guo, Liuhua Zhou, Xiaozhi Zhao   +10 more
wiley   +1 more source

The complete mitochondrial genome of <i>Traccatichthys punctulatus</i> (Cypriniformes: Nemacheilidae) and its phylogenetic status. [PDF]

Mitochondrial DNA B Resour
Ni S, Di F, Huang S.
europepmc   +1 more source

Oral Exposure to Food‐Grade Nanoparticles Poses a Risk of Alzheimer's Disease‐Like Symptoms by Triggering Autophagy Defects in Neurons

Advanced Science, EarlyView.
Three food‐grade nanomaterials induce dysregulated RyR‐Ca2+ signaling through epigenetic modifications. This dysregulation impairs the autophagic clearance process, ultimately leading to abnormal Aβ deposition and increase phosphorylated tau levels.
Jiaxin Shang, Jun Yan, He Lou, Xuanxi Jiang, Ziyue Wang, Yue Gao, Xiaohui Fan, Xiaoyan Lu   +7 more
wiley   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source