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Mitochondrial genome characters

, 2000
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Platyzoan mitochondrial genomes

Molecular Phylogenetics and Evolution, 2013
Platyzoa is a putative lophotrochozoan (spiralian) subtaxon within the protostome clade of Metazoa, comprising a range of biologically diverse, mostly small worm-shaped animals. The monophyly of Platyzoa, the relationships between the putative subgroups Platyhelminthes, Gastrotricha and Gnathifera (the latter comprising at least Gnathostomulida ...
Alexandra R, Wey-Fabrizius, Lars, Podsiadlowski, Holger, Herlyn, Thomas, Hankeln   +3 more
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Mitochondrial genome and longevity

Biochemistry (Moscow), 2016
The mitochondrial genome provides not only respiratory chain function, but it also ensures the impact of mitochondria on nearly all crucial metabolic processes. It is well known that mitochondria regulate aging and lifespan. However, until now there were no direct experimental data concerning the influence of various mitochondrial DNA variants on ...
R A, Zinovkin, M V, Skulachev, V P, Skulachev   +2 more
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Mitochondrial genomes: anything goes

Trends in Genetics, 2003
Abstract Mitochondria have their own genetic system – a vestigial genome originating from an endosymbiotic α-proteobacterial ancestor. The genetic function of mitochondrial DNA (mtDNA) is well-conserved, being involved in a maximum of five mitochondrial processes: invariantly in respiration and/or oxidative phosphorylation and translation, and also in
Gertraud, Burger, Michael W, Gray, B Franz, Lang   +2 more
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The Mitochondrial Genome And Human Mitochondrial Diseases

Journal of the Peripheral Nervous System, 2002
To date, more than 100 point mutations and several hundreds of structural rearrangements of mitochondrial DNA (mtDNA) are known too be connected with characteristic neuromuscular and other mitochondrial syndromes varying from those causing death at the neonatal stage to diseases with late ages of onset. The immediate cause of mitochondrial disorders is
R I, Sukernik, O A, Derbeneva, E B, Starikovskaia, N V, Volod'ko, I E, Mikhaĭlovskaia, I Iu, Bychkov, M, Lott, M, Brown, D, Wallace   +8 more
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The mitochondrial genome and mitochondrial muscle disorders

Current Opinion in Pharmacology, 2001
Mitochondrial disorders represent a multitude of clinically heterogeneous diseases in which the genetic abnormality can involve either a mitochondrial or nuclear gene. In addition to inherited defects, somatic mitochondrial DNA mutations have been implicated in the pathogenesis of neurodegenerative disease, cancer and the ageing process.
A M, Schaefer, R W, Taylor, D M, Turnbull   +2 more
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Mitochondrial genomics flies high

Trends in Ecology & Evolution, 2001
A new pair of papers reports the complete coding sequences for 28 mitochondrial DNAs in Drosophila. By examining the patterns of polymorphism and divergence among functionally distinct classes of synonymous and nonsynonymous nucleotide sites, Bill Ballard provides a comprehensive whole-genome picture of how mtDNA sequence evolution can depart from the ...
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Lingzhi Mitochondrial Genome

2021
The mitochondrial genome is the second genome for eukaryotes. It has essential functions in many cellular processes, including producing energy, signaling, aging, and programmed cell death. Up to now, ten mitochondrial genomes from seven Ganoderma species had been released on the public database. The mitochondrial genomes of each species were described
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The Aspergillus nidulans mitochondrial genome

Current Genetics, 1985
A brief description is provided of the overall organisation of the Aspergillus nidulans mitochondrial genome, as revealed by DNA sequence analysis.
T A, Brown, R B, Waring, C, Scazzocchio, R W, Davies   +3 more
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Genomic Strategies in Mitochondrial Diagnostics

2023
Pathogenic variants in both mitochondrial and nuclear genes contribute to the clinical and genetic heterogeneity of mitochondrial diseases. There are now pathogenic variants in over 300 nuclear genes linked to human mitochondrial diseases. Nonetheless, diagnosing mitochondrial disease with a genetic outcome remains challenging.
Deen D, Alston CL, Hudson G, Taylor RW, Pyle A   +4 more
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