Results 261 to 270 of about 1,628,733 (342)

Targeting IGF1R Overcomes Armored and Cold Tumor Microenvironment and Boosts Immune Checkpoint Blockade in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
IGF1R is highly expressed in the armored & cold tumors, and collagen mediates IGF1R at the transcriptional and post‐translational levels to promote TNBC cell invasion and immune escape and to stabilize its own structure by interacting with the collagen receptor DDR1.
Mengyun Wan, Jie Mei, Yun Cai, Ji Zhou, Ningyi Xue, Ying Jiang, Yan Zhang, Jingjing Huang, Yichao Zhu   +8 more
wiley   +1 more source

Characterization of the complete mitochondrial genome of a rare fungal species <i>Mutinus fleischeri</i> Penz. [PDF]

Mitochondrial DNA B Resour
Song J, Gao Q, Lou FN, Wang PX, Zhang CG, Tang HY, Huang ZP.   +6 more
europepmc   +1 more source

Determination of the complete nucleotide sequence and haplotypes in the D-loop region of the mitochondrial genome in the Oriental white stork, Ciconia boyciana.

, 2000
Yoshihiro Yamamoto, Koichi Murata, Hideo Matsuda, Takahisa Hosoda, Kazuo Tamura, Jun-ichi Furuyama   +5 more
openalex   +2 more sources

Irisin‐Loaded Cerium‐Containing Mesoporous Bioactive Glass for Effective Immunomodulation and Odontogenesis of Dental Pulp Cells

Advanced Science, EarlyView.
The Irisin/Ce‐MBGNs delivery system can slowly release myokine Irisin for vital pulp therapy. Irisin/Ce‐MBGNs can enhance mitochondrial function and promote the differentiation of inflammatory macrophages toward M2‐Mφ, thereby regulating the immune response mechanism of inflamed dental pulp.
Mingxin Wang, Yuxin Yang, Jingyao Guo, Yan Chen, Xiaolin Lu, Guangdong Zhang, Yuli Wang, Minhui Yao, Yue Liu, Qian Ma   +9 more
wiley   +1 more source

Assembly and Comparative Analysis of the Complete Mitochondrial Genome of <i>Bromus inermis</i>. [PDF]

Genes (Basel)
Feng S, Wu Z, Tian C, Yang Y, Gong W, Li Z.   +5 more
europepmc   +1 more source

Ubiquitination‐Dependent LLGL2 Degradation Drives Colorectal Cancer Progression via THBS3 mRNA Stabilization

Advanced Science, EarlyView.
During the progression of CRC, MDM2, as an E3 ubiquitin ligase, promotes the degradation of the LLGL2 protein. Reduced expression of the LLGL2 protein leads to the loss of support for the CNOT1 protein, decreasing the degradation of THBS3 mRNA. The increased THBS3 further activates the PI3K‐Akt pathway, promoting the proliferation and metastasis of CRC.
Jiayan Huang, Tiantian Zhang, Huimin Li, Zidan Li, Shuangshuang Yin, Yiman Liu, Chunze Zhang, Yuling Qiu, Haiyang Yu   +8 more
wiley   +1 more source

Complete Mitochondrial Genome and Its Phylogenetic Analysis of <i>Oides decempunctatus</i> (Coleoptera: Chrysomelidae). [PDF]

Ecol Evol
Zhang H, Wu J, Liu Z, Wei X, Zhuo Z.
europepmc   +1 more source

Complete Sequence of the Mitochondrial DNA of the Primitive Opisthobranch Gastropod Pupa strigosa: Systematic Implication of the Genome Organization

, 2000
Atsushi Kurabayashi, Rei Ueshima
openalex   +1 more source

Developmental Hypoxia Enhances Kidney Organoid Complexity and Maturity

Advanced Science, EarlyView.
The current bottleneck in metanephric mesenchyme (MM)‐derived nephron organoid development is the absence of a connected network of collecting ducts (CD) derived from the ureteric bud (UB). To address this limitation, this study proposes a hypoxia‐based differentiation method that mimics the natural renal developmental environment, enabling the ...
Hyeonji Lim, Dohui Kim, Haejin Yoon, Joo H. Kang, Yong Jun Kim, Dong Sung Kim, Tae‐Eun Park   +6 more
wiley   +1 more source