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Novel Methods for Measuring the Mitochondrial Membrane Potential
2015The mitochondrial membrane potential is a critical parameter for understanding mitochondrial function, but it is challenging to quantitate with current methodologies which are based on the accumulation of cation indicators. Recently we have introduced a new methodology based on the redox poise of the b-hemes of the bc 1 complex.
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Mitochondrial Membrane Potential and the Permeability Transition in Excitotoxicity
Annals of the New York Academy of Sciences, 1999ABSTRACT: Acute neuronal injury caused by activation of glutamate receptors in neurons, or excitotoxicity, can be triggered by the activation of N‐methyl‐D‐aspartate receptors and the entry of large amounts of Ca2+. Recent studies have suggested that mitochondria have a critical role in the excitotoxicity injury mechanism.
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Mitochondrial Membrane Potential and Dynamics
2011Mitochondria are essential for neuronal homeostasis and their dysfunction causes neurodegeneration. Mitochondrial bioenergetics and dynamics ensure ATP supply and Ca2+ buffering throughout neuronal processes, regulating and being reciprocally modulated by synaptic activity.
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Relation Between Mitochondrial Membrane Potential and ROS Formation
2011Mitochondria are considered the main source of reactive oxygen species (ROS) in the cell. For this reason they have been recognized as a source of various pathological conditions as well as aging. Chronic increase in the rate of ROS production is responsible for the accumulation of ROS-associated damages in DNA, proteins, and lipids and may result in ...
Suski JM +5 more
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Antimicrobial Peptides Mediate Apoptosis by Changing Mitochondrial Membrane Permeability
International Journal of Molecular Sciences, 2022Hongji Wang, Chaowen Zhang, Yuzhu Han
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OXPHOS deficiency activates global adaptation pathways to maintain mitochondrial membrane potential
EMBO Reports, 2021Siqi Liu, Tao Cai, She Chen
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The cell biology of mitochondrial membrane dynamics
Nature Reviews Molecular Cell Biology, 2020Marta Giacomello +2 more
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Organic fluorescent probes for detecting mitochondrial membrane potential
Coordination Chemistry Reviews, 2020Xuechen Li, Yuping Zhao, Junling Yin
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