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Exercise Regulates Mitochondrial Quality Control: Maintenance and Remodeling of Skeletal Muscle Homeostasis. [PDF]
Biology (Basel)Zhao H, Chen M.
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Transport of proteins across or into the mitochondrial outer membrane
Biochimica Et Biophysica Acta - Molecular Cell Research, 2010 Mitochondria are surrounded by two biological membranes. The outer mitochondrial membrane contains two major translocators, the TOM40 (TOM) and TOB/SAM complexes for protein translocation across and/or insertion into the outer membrane. The TOM40 complex functions as an entry gate for most mitochondrial proteins, and the TOB/SAM complex as a ...
Toshiya Endo, Koji Yamano
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Biochimica Et Biophysica Acta - Biomembranes, 2009 The yeast proteins Mrs3p and Mrs4p are two closely related members of the mitochondrial carrier family (MCF), which had previously been implicated in mitochondrial Fe(2+) homeostasis. A vertebrate Mrs3/4 homologue named mitoferrin was shown to be essential for erythroid iron utilization and proposed to function as an essential mitochondrial iron ...
Gerlinde Wiesenberger +1 more
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Journal of Molecular Biology, 2007 The mitochondrial outer membrane contains protein import machineries, the translocase of the outer membrane (TOM) and the sorting and assembly machinery (SAM). It has been speculated that TOM or SAM are required for Bax-induced release of intermembrane space (IMS) proteins; however, experimental evidence has been scarce.
Vera Kozjak-Pavlovic +2 more
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Mitochondrial phosphate transport and the N-ethylmaleimide binding proteins of the inner membrane
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1978Mitochondria have been prepared from the flight muscles of mature blow-flies (Sarcophaga bullata). Phosphate transport by these mitochondria, determined by rates of passive swelling in ammonium phosphate, is sensitive to inhibition by N-ethylmaleimide. 20 nmol of N-ethylmaleimide/nmol cytochrome A inhibit the swelling by 90%.
H, Wohlrab, J, Greaney
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Acta Paediatrica, 1983
ABSTRACT. In lysinuric protein intolerance, diamino acid transport is defective at the basolateral membrane of the jejunal and renotubular epithelia. The plasma has depressed concentrations of ornithine and arginine but, in contrast, supranormal levels of another urea cycle intermediate, citrulline.
J, Rajantie, O, Simell, J, Perheentupa
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ABSTRACT. In lysinuric protein intolerance, diamino acid transport is defective at the basolateral membrane of the jejunal and renotubular epithelia. The plasma has depressed concentrations of ornithine and arginine but, in contrast, supranormal levels of another urea cycle intermediate, citrulline.
J, Rajantie, O, Simell, J, Perheentupa
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1995
In part of the patients with a disturbance in the mitochondrial energy metabolism, the defect can not be ascribed to a default in the respiratory chain, citric acid cycle or pyruvate dehydrogenase complex. Incubations of muscle mitochondria with various substrates under different conditions render it likely that defects in transport systems in the ...
Ruitenbeek W +6 more
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In part of the patients with a disturbance in the mitochondrial energy metabolism, the defect can not be ascribed to a default in the respiratory chain, citric acid cycle or pyruvate dehydrogenase complex. Incubations of muscle mitochondria with various substrates under different conditions render it likely that defects in transport systems in the ...
Ruitenbeek W +6 more
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Proteostasis at the mitochondrial outer membrane: Quality control of mitochondrial protein transport
Protein ScienceAbstract Mitochondria are enclosed by a double‐membrane structure composed of the outer and inner membranes, and this architectural organization underlies their diverse cellular functions. In particular, the mitochondrial outer membrane serves as an essential interface between the cytosol and the mitochondrial interior, regulating the
Shunsuke Matsumoto +2 more
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Annals of Nutrition and Metabolism, 1986
The relationships between the structural integrity and functionality of rat liver mitochondrial membranes, and different levels of dietary protein and vitamin A transportation during protein depletion in animals have been investigated. Although the vitamin A content of the protein-depleted diet was 1680 +/- 35 IU/kg diet, and that of the control diet ...
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The relationships between the structural integrity and functionality of rat liver mitochondrial membranes, and different levels of dietary protein and vitamin A transportation during protein depletion in animals have been investigated. Although the vitamin A content of the protein-depleted diet was 1680 +/- 35 IU/kg diet, and that of the control diet ...
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