Results 141 to 150 of about 42,806 (266)

Correction: Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy. [PDF]

Trials, 2022
AIMM Trial Group:, Abouhajar A, Alcock L, Bigirumurame T, Bradley P, Brown L, Campbell I, Del Din S, Faitg J, Falkous G, Gorman GS, Lakey R, McFarland R, Newman J, Rochester L, Ryan V, Smith H, Steel A, Stefanetti RJ, Su H, Taylor RW, Thomas NJP, Tuppen H, Vincent AE, Warren C, Watson G.   +25 more
europepmc   +1 more source

Lipofuscin: The Missing Link in the Worsening of Obstructive Sleep Apnea

The Laryngoscope, Volume 136, Issue 5, Page 2362-2369, May 2026.
Lipofuscin, also known as the age pigment, is a permanent autofluorescent intracellular deposit that accumulates with aging or oxidative stress, thereby interfering with cellular function. This study revealed significantly larger deposits of lipofuscin in the lateral pharyngeal wall muscles of patients with severe obstructive sleep apnea (OSA) compared
Kristine Fahl, Carlos Modesto Vera Palomino, Mauricio da Silva Baptista, Adriano Polican Ciena, Danielle Andrade da Silva Dantas, Luiz Ubirajara Sennes, Marucia Chacur, Michel Burihan Cahali   +7 more
wiley   +1 more source

Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy. [PDF]

Trials, 2022
AIMM Trial Group:, Abouhajar A, Alcock L, Bigirumurame T, Bradley P, Brown L, Campbell I, Del Din S, Faitg J, Falkous G, Gorman GS, Lakey R, McFarland R, Newman J, Rochester L, Ryan V, Smith H, Steel A, Stefanetti RJ, Su H, Taylor RW, Thomas NJP, Tuppen H, Vincent AE, Warren C, Watson G.   +25 more
europepmc   +1 more source

Innate Lymphoid Cells in Tissue Homeostasis and Diseases

MedComm, Volume 7, Issue 5, May 2026.
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan, Heyang Sun, Chenning Li, Qianya Hong, Shuainan Zhu, Ying Yu, Hao Zhang, Kefang Guo   +7 more
wiley   +1 more source

Skeletal Muscle Microbiopsies in Children and Adults—Tolerability, Sample Yield, and Analyzability

Muscle &Nerve, Volume 73, Issue 5, Page 794-799, May 2026.
ABSTRACT Introduction/Aims Traditional methods of sampling skeletal muscle tissue are invasive. This study aimed to evaluate a sub‐millimeter core‐biopsy (microbiopsy) as a potentially more tolerable method, with further regard to tissue yield and analyzability of RNA expression.
Emil Rydell Högelin, Sebastian Edman, Paulo R. Jannig, Axel Löfgren, Kajsa Thulin, Piotr Michno, Jessica Norrbom, Björn A. Alkner, Ferdinand von Walden, Lotta Fornander   +9 more
wiley   +1 more source

Unexplained dyspnea linked to mitochondrial myopathy following military deployment to Southwest Asia and Afghanistan. [PDF]

Physiol Rep, 2023
Onofrei CD, Gottschall EB, Zell-Baran L, Rose CS, Kraus R, Pang K, Krefft SD.   +6 more
europepmc   +1 more source

Intracellular Ca 2+ sensing: role in calcium homeostasis and signaling [PDF]

, 2017
Ca2+ is a ubiquitous intracellular messenger that controls diverse cellular functions but can become toxic and cause cell death. Selective control of specific targets depends on spatiotemporal patterning of the calcium signal and decoding it by multiple,
Bagur, Rafaela, Hajnóczky, György
core   +1 more source

Muscle fibre type shift in COPD: Adaptive, maladaptive or a bit of both?

Experimental Physiology, EarlyView.
Jacob Peter Hartmann, Hannah G. Caldwell, Ulrik Winning Iepsen   +2 more
wiley   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Evidence-based treatment of metabolic myopathy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2014
Objective To evaluate the current treatments and possible adverse reactions of metabolic myopathy, and to develop the best solution for evidence-based treatment.
Yan LIN, Wen-wu ZHANG, Ling LIU
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