Results 161 to 170 of about 914,673 (333)

Protocol for mitochondrial isolation and sub-cellular localization assay for mitochondrial proteins. [PDF]

STAR Protoc, 2023
Zhou D, Zhong S, Han X, Liu D, Fang H, Wang Y.   +5 more
europepmc   +1 more source

Role of Miro1 adaptor protein in mitochondrial mobility between cancer and stromal cells [PDF]

Jaromı́r Novák, Zuzana Nahácka, Gabriela Lopes Oliveira, Petra Brisudová, Sarka Dvorakova, Markéta Dalecká, Verena Puttrich, Lenka Grycová, Luděk Štěpánek, Renata Zobalová, Mikkel G. Terp, Zdeněk Lánský, Paulo J. Oliveira, Henrik J. Ditzel, Michael V. Berridge, Jakub Rohlena, Jiřı́ Neužil   +16 more
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

In fission yeast, 65 non-essential mitochondrial proteins related to respiration and stress become essential in low-glucose conditions. [PDF]

R Soc Open Sci, 2023
Mori A, Uehara L, Toyoda Y, Masuda F, Soejima S, Saitoh S, Yanagida M.   +6 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine
Mitochondria are the foundation of cellular energy metabolism and are crucial for cell growth and development. Mitochondrial dysfunction can disrupt cellular energy metabolism and normal cellular functions, contributing to the onset of related diseases ...
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
doaj   +1 more source

Neurodegeneration-associated mitochondrial proteins, CHCHD2 and CHCHD10-what distinguishes the two? [PDF]

Front Cell Dev Biol, 2022
Ikeda A, Imai Y, Hattori N.
europepmc   +1 more source

Fluorescent Visualization of In Vitro Mitochondrial DNA Transcription [PDF]

, 2019
Mitochondria are important organelles within eukaryotic cells especially for their role in metabolism and ATP production by the oxidative phosphorylation (OXPHOS) pathway. In human cells there are approximately 80 protein subunits that make up the OXPHOS
Bruce, Kelsey
core   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins. [PDF]

Genome Res, 2023
Avolio R, Agliarulo I, Criscuolo D, Sarnataro D, Auriemma M, De Lella S, Pennacchio S, Calice G, Ng MY, Giorgi C, Pinton P, Cooperman BS, Landriscina M, Esposito F, Matassa DS.   +14 more
europepmc   +1 more source