Nascent mitochondrial proteins initiate the localized condensation of cytosolic protein aggregates on the mitochondrial surface. [PDF]
Liu Q+9 more
europepmc +1 more source
Incorporation in vivo of 14C-Labelled Amino Acids into the Proteins of Mitochondrial Ribosomes from Neurospora crassa Sensitive to Cycloheximide and Insensitive to Chloramphenicol [PDF]
Walter Neupert+4 more
openalex +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Roles of O-GlcNAcylation in Mitochondrial Homeostasis and Cardiovascular Diseases
Protein posttranslational modifications are important factors that mediate the fine regulation of signaling molecules. O-linked β-N-acetylglucosamine-modification (O-GlcNAcylation) is a monosaccharide modification on N-acetylglucosamine linked to the ...
Zhen Qiu+4 more
doaj +1 more source
Mitochondrial proteins encoded by the 22q11.2 neurodevelopmental locus regulate neural stem and progenitor cell proliferation. [PDF]
Campbell PD, Lee I, Thyme S, Granato M.
europepmc +1 more source
The Dicyclohexylcarbodiimide‐Binding Protein of the Mitochondrial ATPase Complex from Neurospora crassa and Saccharomyces cerevisiae [PDF]
Walter Sebald+2 more
openalex +1 more source
CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki+2 more
wiley +1 more source
Mitochondrial Ribosomal Proteins and Cancer
Mitochondria play key roles in maintaining cell life and cell function, and their dysfunction can lead to cell damage. Mitochondrial ribosomal proteins (MRPs) are encoded by nuclear genes and are assembled within the mitochondria.
Huiyi Wu+5 more
doaj +1 more source
Systematic Approaches to Study Eclipsed Targeting of Proteins Uncover a New Family of Mitochondrial Proteins. [PDF]
Mark M+9 more
europepmc +1 more source
Mitophagy, the selective degradation of damaged mitochondria, is crucial for cellular health and function. This study introduces a rapid and efficient flow cytometry method using GFP‐BNIP3L/NIX to accurately quantify mitophagy. Our approach can be adapted to use any fluorescent‐tagged selective autophagy receptor, enabling direct and rapid analysis of ...
Mija Marinković+3 more
wiley +1 more source