Hormone deprivation alters mitochondrial function and lipid profile in the hippocampus [PDF]
, 2017 Mitochondrial dysfunction is a common hallmark in aging. In the female, reproductive senescence is characterized by loss of ovarian hormones, many of whose neuroprotective effects converge upon mitochondria.
Alvarez, Silvia +7 more
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Life, 2021 Diabetes mellitus (DM) is the most severe metabolic disease that reached the level of a global pandemic and is associated with high cardiovascular morbidity. Statins are the first–line lipid–lowering therapy in diabetic patients with or without a history
Vlad Florian Avram +9 more
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Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin [PDF]
, 2020 High expression of Ki67, a proliferation marker, is associated with reduced endometrial cancer-specific survival. Pre-surgical metformin reduces tumour Ki-67 expression in some women with endometrial cancer. Metformin's anti-cancer activity may relate to
Crosbie, EJ +9 more
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Human Influenza A Virus (IAV) Decreases Mitochondrial Respiration of Infected MDCK Cell [PDF]
Iranian Journal of Public Health, 2005 Studies of interaction between viruses and mitochondria have shown that they can affect the mitochondria and induce mitochondrial alterations. Sometimes this interaction leads to induction or inhibition of apoptosis in infected cells. Interaction between
M Derakhshan, GEN Kass, MJ Carter
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Analysis of mitochondrial respiration and ATP synthase in frozen brain tissues
Heliyon, 2023 Studying mitochondrial respiration capacity is essential for gaining insights into mitochondrial functions. In frozen tissue samples, however, our ability to study mitochondrial respiration is restricted by damage elicited to the inner mitochondrial ...
Pamela J. Yao +3 more
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Bioenergetics Consequences of Mitochondrial Transplantation in Cardiomyocytes. [PDF]
, 2020 Background Mitochondrial transplantation has been recently explored for treatment of very ill cardiac patients. However, little is known about the intracellular consequences of mitochondrial transplantation.
Ali Pour, Paria +2 more
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Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart [PDF]
, 2014 This is the final version. It was first published by Wiley in The Journal of Physiology at http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2014.275263/abstract.Hypoxic exposure is associated with impaired cardiac energetics in humans and altered ...
Andrew J. Murray +11 more
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Site-1 protease inhibits mitochondrial respiration by controlling the TGF-β target gene Mss51
Cell Reports, 2023 Summary: The mitochondrial response to changes in cellular energy demand is necessary for cellular adaptation and organ function. Many genes are essential in orchestrating this response, including the transforming growth factor (TGF)-β1 target gene Mss51,
Muhammad G. Mousa +8 more
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Cell Reports, 2019 Summary: Regulatory T cells (Tregs) are pivotal for immune suppression. Cellular metabolism is important for Treg homeostasis and function. However, the exact role of mitochondrial respiration in Tregs remains elusive.
Zheng Fu +10 more
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Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis [PDF]
, 2013 Funding This study was funded by the Medical Research Council (Grant number G0800149). Research material from this study is not available. Acknowledgement We are very grateful to Dr Robin A.J. Smith, Department of Chemistry, University of Otago, Dunedin,
Galley, H. F. +3 more
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