Results 51 to 60 of about 645,590 (301)

(A–D) Mitochondrial respiration.

, 2014
Mitochondrial respiratory activities, from endogenous substrates (A), succinate (B) and ascorbate (C), and mitochondrial respiratory control ratios from endogenous respiration (D) in ileo-ileal (gray bars) and colo-colic (white bars) anastomosis. In each
Nicola Sardaro (516604), Germana Lissidini (516601), Francesco Staffieri (516605), Angela Gurrado (516597), Piero Portincasa (44294), Antonio Crovace (516606), Maria Rosaria Carratù (338353), Luigi Greco (192364), Maria Antonietta De Salvia (516602), Andrea Marzullo (516599), Leonilde Bonfrate (516603), Salvatore Scacco (516598), Lucantonio Debellis (373662), Giuseppe Piccinni (516600), Mario Testini (516596)   +14 more
core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Cancer cells differentially modulate mitochondrial respiration to alter redox state and enable biomass synthesis in nutrient-limited environments

eLife
The cell NAD+/NADH ratio can constrain biomass synthesis and influence proliferation in nutrient-limited environments. However, which cell processes regulate the NAD+/NADH ratio is not known.
Sarah M Chang, Muhammad Bin Munim, Sonia E Trojan, Huel Cox III, Anna Shevzov-Zebrun, Keene L Abbott, Renee Chang, Matthew G Vander Heiden   +7 more
doaj   +1 more source

A simple method for mitochondrial respiration and calcium uptake assessment in pollen tubes

MethodsX, 2019
Key mitochondrial processes are known to be widely conserved throughout the eukaryotic domain. However, the scarce availability of working materials may restrict the assessment of such mitochondrial activities in several working models.
Diana J. Ortiz-Jiménez, Casandra M. López-Aquino, Cesar Flores-Herrera, Gisela Preciado-Linares, Israel Gonzalez-Vizueth, Roeb García-Arrazola, Daniela Araiza-Olivera, Manuel Gutiérrez-Aguilar   +7 more
doaj   +1 more source

Functional mitochondrial respiration is essential for glioblastoma tumour growth [PDF]

Horizontal transfer of mitochondria from the tumour microenvironment to cancer cells to support proliferation and enhance tumour progression has been shown for various types of cancer in recent years. Glioblastoma, the most aggressive adult brain tumour,
Vanatko, O, Brisudova, P, Novak, J, Stojanovic, D, Oliveira, GL, Jirak, D, Dvorakova, S, Foltynova, A, Chalupsky, K, Kucera, L, Jirat-Ziolkowska, N, Nahacka, Z, Endaya, B, et al., Truksa, J, Kubiskova, M, Jirak, Daniel, Tiano, Luca, Foltynova, Alice, Anderova, Miroslava, Jirat-Ziolkowska, Natalia, Endaya, Berwini, Prochazka, Jan, Berridge, Michael V., Chalupsky, Karel, Novak, Jaromir, Truksa, Jaroslav, Vanatko, Ondrej, Mengarelli, Francesco, Dvorakova, Sarka, Orlando, Patrick, Neuzil, Jiri, Oliveira, Gabriela Lopes, Grasso, Carole, Brisudova, Petra, Nahacka, Zuzana, Klima, Krystof, Zobalova, Renata, Sedlacek, Radislav, Oliveira, Paulo J., Stojanovic, Dana, Kucera, Lukas, Kubiskova, Monika   +42 more
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Research note: using rapid adjustments of mitochondrial function to dietary changes as an indicator? an experimental test in slower growing broiler hybrid

Poultry Science
This study investigated the effects of dietary energy and lysine levels on mitochondrial respiration and its association with growth performance in slower-growing broiler chickens.
Ali Kiani, Heidi Högel, Suvi Ruuskanen
doaj   +1 more source

Kinetics of the inhibition of mitochondrial respiration by NO

FEBS Letters, 1997
The kinetics of the inhibition of mitochondrial respiration by NO was examined in isolated mitochondria (here obtained from rat brown adipose tissue). The K i of NO for the inhibition was ∼27 nM; the IC50 of NO increased in proportion to the square of an increase in O2 tension.
Koivisto, Ari, Matthias, Anita, Bronnikov, Gennady, Nedergaard, Jan   +3 more
openaire   +2 more sources

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Cortical Mitochondrial Respiration Following Microanastomosis [PDF]

, 1977
Cortical Mitochondrial Respiration Following Microanastomosis. G. Austin, G. Haugen, D. Brown, E. Lichter, W. Hayward. Conference presentation. American Association of Neurological Surgeons. Toronto, Canada, April, 1977.
Austin, G., Lichter, E., Haugen, G., Hayward, W., Brown, D.   +4 more
core   +1 more source