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Young apple polyphenol extract prevents diabetic cognitive dysfunction by promoting TET2-mediated active DNA demethylation in the brain of diabetic mice

Frontiers in Nutrition
IntroductionDiabetic cognitive dysfunction (DCD) refers to the impairment of cognitive function resulting from diabetes. The increasing prevalence of diabetes and the aging population have rendered DCD a significant threat to brain health.
Jiacheng Fang, Jiacheng Fang, Xiaochen Zhang, Zhongshi Qi, Zhongshi Qi, Liying Zhou, Yuntiao Chen, Qingxin Li, Run Liu, Hongzhuan Yu   +9 more
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Ion channels and atrial fibrillation: mitophagy as a key mediator

Frontiers in Physiology
BackgroundThe prevalence of atrial fibrillation (AF) is increasing due to the aging population. Mitophagy is crucial for maintaining cardiomyocyte function, while ion channels play a key role in cardiac electrical activity.
Xize Wu, Xiaorui Yan, Ruoxi Ma, Qiuying Wu, Xue Pan, Qihua Wu, Jiaqi Ren, Yuxi Huang, Shan Gao, Yue Li, Lihong Gong   +10 more
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RPS9M, a Mitochondrial Ribosomal Protein, Is Essential for Central Cell Maturation and Endosperm Development in Arabidopsis

Frontiers in Plant Science, 2017
During double fertilization of angiosperms, the central cell of the female gametophyte fuses with a sperm cell to produce the endosperm, a storage tissue that nourishes the developing embryo within the seed.
Changqing Lu, Feng Yu, Lianfu Tian, Xiaoying Huang, Hong Tan, Zijing Xie, Xiaohua Hao, Dongping Li, Sheng Luan, Sheng Luan, Liangbi Chen   +10 more
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The complete mitochondrial genome of Pareuchiloglanis feae (Siluriformes, Sisoridae, Pareuchiloglanis): genome characterization and phylogenetic analysis

Mitochondrial DNA. Part B. Resources, 2022
Pareuchiloglanis feae is mainly distributed in Irrawaddy (China and Myanmar), Salween (China and Myanmar), and the Yangtze River drainage areas. In this study, the complete mitochondrial genome of P.
Sheng Zeng, Xue Wang, Wei Liu, Yan Xiang, Lu Zhou   +4 more
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The complete mitochondrial genome of Metapenaeus ensis

Mitochondrial DNA. Part B. Resources, 2019
The complete mitochondrial genome sequence of Metapenaeus ensis was obtained by PCR, containing 37 genes with 13 protein-coding genes, 22 transfer RNAs (tRNAs), two ribosomal RNAs (rRNAs) and a non-coding control region.
Maocang Yan, Lihua Hu, Min Zhang, Dewei Ji, Qianjin Zhou, Jiongming Zhang, Jiong Chen   +6 more
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Characterization of the leafhopper mitogenome of Mileewa alara (Hemiptera: Cicadellidae: Mileewinae) and its phylogenetic analysis

Mitochondrial DNA. Part B. Resources, 2021
The mitogenome data of leafhopper species Mileewa alara was assembled and annotated in this study. The results shows that length of M. alara is 16020 bp, consist of 13 protein-coding genes (PCGs), 22 tRNA genes, 2 rRNA genes, and one control region.
Hongli He, Maofa Yang
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The role of reactive oxygen species-mitophagy regulation in the treatment of osteoarthritis by active Chinese herbal medicine monomers: a review

Frontiers in Medicine
The primary pathological features of osteoarthritis (OA) involve articular cartilage degradation and structural damage, coupled with osteophyte formation and inflammatory responses.
Runjia Lei, Chaoqing Zhou
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Trypanocidal Activity of Dual Redox-Active Quinones: Trypanosoma cruzi Mitochondrion as a Target Organelle In Vitro and Anti-Inflammatory Properties In Vivo

Pathogens
Chagas disease is caused by the protozoan Trypanosoma cruzi, and its current treatment is limited to the use of two nitroderivatives, benznidazole (Bz) and nifurtimox; however, their toxicity often leads to discontinuation, justifying the search for new ...
Raquel B. Duarte, Victor F. S. Ramos, Juliana M. C. Barbosa, Gabriel M. Oliveira, Emilay B. T. Diogo, Renata G. Almeida, Alastair J. J. Lennox, Eufrânio N. da Silva Júnior, Yasmin Pedra-Rezende, Rubem F. S. Menna-Barreto   +9 more
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Dietary β-Sitosterol Improves Growth Performance, Meat Quality, Antioxidant Status, and Mitochondrial Biogenesis of Breast Muscle in Broilers

Animals, 2019
The present study evaluated effects of β-sitosterol on growth performance, meat quality, oxidative status, and mitochondrial biogenesis of breast muscle in broilers. One-day-old chicks were allocated to five treatments of six replicates.
Yefei Cheng, Yueping Chen, Jun Li, Hengman Qu, Yurui Zhao, Chao Wen, Yanmin Zhou   +6 more
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The mitochondrial genome of the endemic Brazilian paradoxical frog Pseudis tocantins (Hylidae)

Mitochondrial DNA. Part B. Resources, 2018
In this work, we present for the first time the mitochondrial genome of a paradoxical frog (Pseudis tocantins). This genome is 15.56 kb, excluding the control region, and is similar in gene content to other hylid mitogenomes. Maximum likelihood analysis,
Kaleb Pretto Gatto, Jeramiah J. Smith, Luciana Bolsoni Lourenço   +2 more
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