Results 1 to 10 of about 397,286 (332)
Identification of Fis1 Interactors in
mBio, 2020 Toxoplasma gondii’s single mitochondrion is very dynamic and undergoes morphological changes throughout the parasite’s life cycle. During parasite division, the mitochondrion elongates, enters the daughter cells just prior to cytokinesis, and undergoes ...
Kylie Jacobs +2 more
doaj +4 more sources
Of mitochondrion and COVID-19 [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction.
Khalid Omer Alfarouk +15 more
doaj +5 more sources
Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery
Nature Communications, 2021 The mitochondrion is an important sub-cellular organelle responsible for the cellular energetic source and processes. Owing to its unique sensitivity to heat and reactive oxygen species, the mitochondrion is an appropriate target for photothermal and ...
Lei Jiang +6 more
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Nature Communications, 2021 Mitochondrial division is not an autonomous event but involves multiple organelles, including the endoplasmic reticulum (ER) and lysosomes. Whereas the ER drives the constriction of mitochondrial membranes, the role of lysosomes in mitochondrial division
Peter Kijun Kim, Peter K Kim
exaly +2 more sources
AMPK regulates ARF1 localization to membrane contact sites to facilitate fatty acid transfer between lipid droplets and mitochondria [PDF]
Cell Death and DiseaseLipid droplet (LD) -mitochondrion contacts play a crucial role in regulating energy metabolism and fatty acid oxidation in skeletal muscle cells. However, the proteins that regulate these interactions remain poorly understood.
Lupeng Chen +5 more
doaj +2 more sources
What Is Nuclear Factor Kappa B (NF-κB) Doing in and to the Mitochondrion?
Frontiers in Cell and Developmental Biology, 2019 A large body of literature supports the idea that nuclear factor kappa B (NF-κB) signaling contributes to not only immunity, but also inflammation, cancer, and nervous system function. However, studies on NF-κB activity in mitochondrial function are much
Benedict C Albensi
exaly +2 more sources
Trypanocidal Activity of Dual Redox-Active Quinones: Trypanosoma cruzi Mitochondrion as a Target Organelle In Vitro and Anti-Inflammatory Properties In Vivo [PDF]
PathogensChagas disease is caused by the protozoan Trypanosoma cruzi, and its current treatment is limited to the use of two nitroderivatives, benznidazole (Bz) and nifurtimox; however, their toxicity often leads to discontinuation, justifying the search for new ...
Raquel B. Duarte +9 more
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Nature Communications, 2017 Characterizing the long-term nanometer-scale interactions between lysosomes and mitochondria in live cells is essential for understanding their functions but remains challenging due to limitations of the existing fluorescent probes. Here, we develop cell-
Yubing Han, Meng Zhang, Yu-Hui Zhang
exaly +2 more sources