Results 1 to 10 of about 354,044 (299)
Of mitochondrion and COVID-19 [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction.
Khalid Omer Alfarouk +15 more
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Towards a Synthetic Mitochondrion [PDF]
CHIMIA, 2018 Our group at the University of Bern uses biochemical and biophysical techniques to unravel details of the molecular mechanism of membrane proteins.
Olivier Biner +3 more
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Pyrophosphate homeostasis in multiple subcellular compartments is essential in Plasmodium falciparum [PDF]
mBioPyrophosphate is a byproduct of numerous cellular reactions that use ATP or other nucleoside triphosphates to synthesize DNA, RNA, protein, and various molecules.
Ikechukwu Nwankwo, Hangjun Ke
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AMPK regulates ARF1 localization to membrane contact sites to facilitate fatty acid transfer between lipid droplets and mitochondria [PDF]
Cell Death and DiseaseLipid droplet (LD) -mitochondrion contacts play a crucial role in regulating energy metabolism and fatty acid oxidation in skeletal muscle cells. However, the proteins that regulate these interactions remain poorly understood.
Lupeng Chen +5 more
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The selfish mitochondrion [PDF]
Cell Calcium, 2021 Mitochondria match ATP supply to fluctuations in cellular energy requirements. Cellular energy requirements are often signaled to mitochondria by increases in the cytoplasmic concentration of Ca2+ ions. These increases in Ca2+ reach the mitochondrial matrix to regulate the proteins, enzymes and transporters required for mitochondrial ATP synthesis ...
McCarron, John G., Wilson, Calum
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Optical Properties and Interference Effects of the Lens Mitochondrion
Membranes, 2023 The lens mitochondrion of the tree shrew, located along the optical pathway between the lens and photoreceptors, has been investigated. The results suggest that the lens mitochondrion acts as a quasi-bandgap or imperfect photonic crystal.
Felix Margadant +3 more
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Cells, 2021 Emerging evidence suggests that mitochondrion–endoplasmic reticulum (ER) and mitochondrion–lipid droplet (LD) contact sites are critical in regulating lipid metabolism in cells.
Xiaowen Ma +4 more
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Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery
Nature Communications, 2021 The mitochondrion is an important sub-cellular organelle responsible for the cellular energetic source and processes. Owing to its unique sensitivity to heat and reactive oxygen species, the mitochondrion is an appropriate target for photothermal and ...
Lei Jiang +6 more
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Inventory and Evolution of Mitochondrion-localized Family A DNA Polymerases in Euglenozoa
Pathogens, 2020 The order Trypanosomatida has been well studied due to its pathogenicity and the unique biology of the mitochondrion. In Trypanosoma brucei, four DNA polymerases, namely PolIA, PolIB, PolIC, and PolID, related to bacterial DNA polymerase I (PolI), were ...
Ryo Harada +10 more
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Organellar Evolution: A Path from Benefit to Dependence
Microorganisms, 2022 Eukaryotic organelles supposedly evolved from their bacterial ancestors because of their benefits to host cells. However, organelles are quite often retained, even when the beneficial metabolic pathway is lost, due to something other than the original ...
Miroslav Oborník
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