Results 91 to 100 of about 354,115 (299)

Mitochondrion of oxymonads [PDF]

, 2011
Oxymonads are among the last larger eukaryotic groups in which mitochondrion-like organelles were not detected. Among almost one million transcriptome sequences of oxymonad Monocercomonoides we found sequences for only three proteins commonly associated ...
Vacek, Vojtěch
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

The Effect of a 7-Week Training Period on Changes in Skin NADH Fluorescence in Highly Trained Athletes

Applied Sciences, 2020
The study aimed to evaluate the changes of nicotinamide adenine dinucleotide (NADH) fluorescence in the reduced form in the superficial skin layer, resulting from a 7-week training period in highly trained competitive athletes (n = 41).
Olga Bugaj, Krzysztof Kusy, Adam Kantanista, Paweł Korman, Dariusz Wieliński, Jacek Zieliński   +5 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major [PDF]

, 2012
Macroautophagy has been shown to be important for the cellular remodelling required for Leishmania differentiation. We now demonstrate that L. major contains a functional ATG12-ATG5 conjugation system, which is required for ATG8-dependent autophagosome ...
Williams, Roderick A M, Mottram, Jeremy C, Roderick A M Williams, Benjamin Cull, Mottram Jeremy C., Coombs, Graham H, Williams Roderick A. M., Cull Benjamin, Terry K Smith, Jeremy C. Mottram (112563), Graham H. Coombs (164011), Smith Terry K., Terry K. Smith (112550), Mottram, Jeremy C., Benjamin Cull (164010), Coombs Graham H., Coombs, Graham H., Smith, Terry K., Jeremy C Mottram, Smith, Terry K, Cull, Benjamin, Williams, Roderick A. M., Roderick A. M. Williams (164005), Graham H Coombs   +23 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Determination of the cristae number per mitochondrion and the relative intracristae surface area (intracristae surface area per mitochondrion surface area, expressed as % ratio). [PDF]

, 2015
Mean values ± SD are from analysis of one hundred mitochondria randomly selected from inclusions obtained from three independent biological samples.
Marcello Marelli (759717), Gianpiero Vigani (123539), Irene Murgia (759719), Graziano Zocchi (123553), Anna Maria Ferretti (759714), Mauro Maver (759718), Francesca Cantele (759715), Dario Maffi (759716), Franco Faoro (759713)   +8 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum [PDF]

, 2007
Lipoic acid (LA) is an essential cofactor of α-keto acid dehydrogenase complexes (KADHs) and the glycine cleavage system. In Plasmodium, LA is attached to the KADHs by organelle-specific lipoylation pathways.
Ryan Bissett, Carsten Wrenger, Gunther, M, Storm Janet, McMillan, Paul, Günther, S, Müller, S, Wallace, L., Muller, S., Patzewitz, Eva-Maria, Paul J McMillan, Lynsey Wallace, Wrenger, C., Günther, S., Bissett Ryan, Wrenger, Carsten, Smith, T.K., Muller, Sylke, McMillan Paul J, Bissett, Ryan, Guenther, Svenja, McMillan, Paul J., Smith, Terry, Sylke Müller, Patzewitz, E.-M., Terry K Smith, Storm, J., Günther Svenja, Storm, Janet, Svenja Günther, Patzewitz, EM, Wallace, Lynsey, Storm, J, McMillan, PJ, Patzewitz Eva-Maria, Mueller, Sylke, McMillan, P.J., Eva-Maria Patzewitz, Wallace Lynsey, Bissett, R, Wrenger, C, Janet Storm, Smith Terry K, Smith, TK, Wrenger Carsten, Smith, Terry K, Wallace, L, Bissett, R., Müller Sylke   +48 more
core   +1 more source