Results 91 to 100 of about 367,263 (290)

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu   +10 more
wiley   +1 more source

Mitochondrion-Related Organelles in Eukaryotic Protists

open access: yes, 2010
The discovery of mitochondrion-type genes in organisms thought to lack mitochondria led to the demonstration that hydrogenosomes share a common ancestry with mitochondria, as well as the discovery of mitosomes in multiple eukaryotic lineages. No examples
Patricia J. Johnson, April M. Shiflett
core   +1 more source

AIFM2 (apoptosis-inducing factor, mitochondrion-associated, 2) [PDF]

open access: yes, 2010
Review on AIFM2 (apoptosis-inducing factor, mitochondrion-associated, 2), with data on DNA, on the protein encoded, and where the gene is ...
Varecha, M, M Varecha
core   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren   +5 more
wiley   +1 more source

Role of the Mitochondrion in Programmed Necrosis [PDF]

open access: yesfrontiers in physiology, 2010
In contrast to the "programmed" nature of apoptosis and autophagy, necrotic cell death has always been believed to be a random, uncontrolled process that leads to the "accidental" death of the cell. This dogma, however, is being challenged and the concept of necrosis also being "programmed" is gaining ground.
openaire   +3 more sources

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park   +5 more
wiley   +1 more source

Independence from kinetoplast DNA maintenance and expression is associated with multi-drug resistance in Trypanosoma brucei in vitro [PDF]

open access: yes, 2014
It is well known that several anti-trypanosomatid drugs accumulate in the parasite's mitochondrion, where they often bind to the organellar DNA, the kinetoplast.
Schnaufer, Achim; id_orcid   +1 more
core   +1 more source

Sustainable Poly(Lactic Acid)/Graphene Oxide Bioelectronic Platform for Neurotransmitters Sensing and Tunable Stimulation of Astrocytes

open access: yesAdvanced Materials, EarlyView.
This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà   +15 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Mitochondrion in a cone photoreceptor pedicle: movie

open access: yes, 2014
Presents movie showing the three-dimensional details of cone pedicle mitochondria generated using electron tomography. Pedicles averaged five medium-sized mitochondria clustered far from the active zones.
Perkins, Guy A.   +3 more
core  

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