Results 111 to 120 of about 367,263 (290)
Advanced Science, EarlyView.This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang +16 more
wiley +1 more source
Complete mitochondrial genome of Haematopus ostralegus (Charadriiformes: Haematopodidae)
Mitochondrial DNA. Part B. Resources, 2017 The Eurasian oystercatcher (Haematopus ostralegus), Near Threatened in the IUCN red list, was designated classified endangered species II by the Ministry of Environment of Korea and a Natural Monument (No.
Mu-Yeong Lee +4 more
doaj +1 more source
Advanced Science, EarlyView.This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha +5 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2019 The northern anchovy, Engraulis mordax, is a small planktivorous fish from the northeastern Pacific Ocean that is an important forage for fishes, birds, and marine mammals, and is also the target of a commercial fishery.
Olivia H. Lewis, Sean C. Lema
doaj +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Sirtuin 3 in diabetic kidney disease: mechanisms and pharmacotherapy
Renal FailureDiabetic kidney disease (DKD) is a microvascular complication of diabetes and a major cause of kidney failure; current treatment methods still need improvement. Sirtuin 3 (SIRT3) is an NAD+-dependent protein deacetylase located in the mitochondria, where
Yinfeng Chen +4 more
doaj +1 more source
The HA89 fertile line complete mitochondrion sequence
, 2018 The complete mitochondrion sequence of the HA89 fertile line of sunflower (Helianthus annuus L) in FASTA format.
Tatiana Tatarinova (159755) +1 more
core +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Microglial CARD19 ameliorates post-stroke neuroinflammation by stabilizing mitochondrial cristae
Neural Regeneration ResearchMicroglia are the first immune cells that are activated in the brain following ischemic stroke. Mitochondrial dysfunction exacerbates microglia-mediated neuroinflammation post-stroke.
Yujie Hu +10 more
doaj +1 more source
The return of the mitochondrion [PDF]
The Biochemist, 2005 For a fresh-faced (well, apart from the beard) PhD graduate in 1989, mitochondrial bioenergetics might have seemed a strange choice of research path. Flushed with the general acceptance of the chemiosmotic theory, many felt that the area had passed its heyday. With the publication of its ‘bible’ (Bioenergetics, the definitive textbook by David Nicholls)
openaire +1 more source