Results 101 to 110 of about 367,263 (290)

Structural features of a mitochondrion captured spanning 2 varicosities (“Var”).

, 2018
(A) A 10-nm slice through a 3D tomographic reconstruction showing a mitochondrion spanning 2 closely spaced varicosities connected by a short (approximately 100 nm) axon segment. An expanded region of the red box shown in (A) reveals the tubulated nature
Tara D. Fischer (5753723), Pramod K. Dash (246530), Jun Liu (42548), M. Neal Waxham (211851)   +3 more
core   +1 more source

CPP–PEG‐Guided Surface Engineering of Mitochondria Enables Efficient Cellular Uptake and Respiratory Modulation

Advanced Materials Interfaces, EarlyView.
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi, Yukari Muramatsu, Akihiro Nakaya, Yuji Maruo, Rick C. Tsai, Masashi Suganuma, Hisashi Ohta, Atsuhito Takeda, Hideyoshi Harashima, Yuma Yamada   +9 more
wiley   +1 more source

COMPARTMENTATION OF THE MITOCHONDRION [PDF]

Proceedings of the National Academy of Sciences, 1965
G, BRIERLEY, D E, GREEN
openaire   +2 more sources

ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major [PDF]

, 2012
Macroautophagy has been shown to be important for the cellular remodelling required for Leishmania differentiation. We now demonstrate that L. major contains a functional ATG12-ATG5 conjugation system, which is required for ATG8-dependent autophagosome ...
Williams, Roderick A M, Mottram, Jeremy C, Roderick A M Williams, Benjamin Cull, Mottram Jeremy C., Coombs, Graham H, Williams Roderick A. M., Cull Benjamin, Terry K Smith, Jeremy C. Mottram (112563), Graham H. Coombs (164011), Smith Terry K., Terry K. Smith (112550), Mottram, Jeremy C., Benjamin Cull (164010), Coombs Graham H., Coombs, Graham H., Smith, Terry K., Jeremy C Mottram, Smith, Terry K, Cull, Benjamin, Williams, Roderick A. M., Roderick A. M. Williams (164005), Graham H Coombs   +23 more
core   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Mitochondrion in a cone photoreceptor pedicle: movie

, 2008
Presents movie showing the three-dimensional details of cone pedicle mitochondria generated using electron tomography. Pedicles averaged five medium-sized mitochondria clustered far from the active zones.
Perkins, Guy A., Ellisman, Mark H., Poquiz, Patrick H., Fox, Donald A.   +3 more
core  

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Complete mitochondrial genome of the green-lipped mussel, Perna canaliculus (Mollusca: Mytiloidea), from long nanopore sequencing reads

Mitochondrial DNA. Part B. Resources, 2018
We describe here the first complete genome assembly of the New Zealand green-lipped mussel, Perna canaliculus, mitochondrion. The assembly was performed de novo from a mix of long nanopore sequencing reads and short sequencing reads. The genome is 16,005 
Louis Ranjard, Thomas K. F. Wong, Carsten Külheim, Allen G. Rodrigo, Norman L. C. Ragg, Selina Patel, Brendon J. Dunphy   +6 more
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Complete mitochondrial genome of Siberian musk deer Moschus moschiferus (Artiodactyla: Moschidae) and phylogenetic relationship with other moschus species

Mitochondrial DNA. Part B. Resources, 2017
The Siberian musk deer, Moschus moschiferus, is an Endangered species in South Korea due to its decreasing population size caused by illegal hunting and habitat destruction. In this study, the complete mitochondrial genome of M.
Sang-In Kim, Mu-Yeong Lee, Hey Sook Jeon, Sang-Hoon Han, Junghwa An   +4 more
doaj   +1 more source