Results 41 to 50 of about 110,678 (189)

Presence of a Mitovirus Is Associated with Alteration of the Mitochondrial Proteome, as Revealed by Protein–Protein Interaction (PPI) and Co-Expression Network Models in Chenopodium quinoa Plants

Biology, 2022
Plant mitoviruses belong to Mitoviridae family and consist of positive single-stranded RNA genomes replicating exclusively in host mitochondria.
Dario Di Silvestre, Giulia Passignani, Rossana Rossi, Marina Ciuffo, Massimo Turina, Gianpiero Vigani, Pier Luigi Mauri   +6 more
doaj   +1 more source

Sabotage at the Powerhouse? Unraveling the Molecular Target of 2-Isopropylbenzaldehyde Thiosemicarbazone, a Specific Inhibitor of Aflatoxin Biosynthesis and Sclerotia Development in Aspergillus flavus, Using Yeast as a Model System

Molecules, 2019
Amongst the various approaches to contain aflatoxin contamination of feed and food commodities, the use of inhibitors of fungal growth and/or toxin biosynthesis is showing great promise for the implementation or the replacement of conventional pesticide ...
Cristina Dallabona, Marianna Pioli, Giorgio Spadola, Nicolò Orsoni, Franco Bisceglie, Tiziana Lodi, Giorgio Pelosi, Francesco Maria Restivo, Francesca Degola   +8 more
doaj   +1 more source

Organellar Evolution: A Path from Benefit to Dependence

Microorganisms, 2022
Eukaryotic organelles supposedly evolved from their bacterial ancestors because of their benefits to host cells. However, organelles are quite often retained, even when the beneficial metabolic pathway is lost, due to something other than the original ...
Miroslav Oborník
doaj   +1 more source

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g [PDF]

, 2009
Crista junctions (CJs) are important for mitochondrial organization and function, but the molecular basis of their formation and architecture is obscure.
Al-Amoudi, Allen, Andreas S. Reichert, Andreja Vasiljev-Neumeyer, Arnold, Bornhövd, Buzhynskyy, Christian Körner, Cipolat, Claros, Cyrklaff, Daems, DiMauro, Dubochet, Dudkina, Dudkina, Emaus, Fawcett, Frank Vogel, Frey, Frey, Frezza, Ghaemmaghami, Gilkerson, Hegerl, Herlan, Herlan, Icho, John, Mannella, Mannella, Mannella, Mannella, Marek Cyrklaff, Meeusen, Meier, Merkwirth, Merkwirth, Minauro-Sanmiguel, Mokranjac, Munn, Nadine Mendl, Nicastro, Nickell, Odgren, Olichon, Paumard, Perkins, Perkins, Perkins, Pon, Puig, Ravi Jagasia, Regina Rabl, Renken, Roland Scholz, Rowley, Schagger, Scorrano, Sherman, Sirrenberg, Strauss, Taylor, Thomas Keil, Tokuyasu, Velours, Vincent Soubannier, Vogel, Wach, Wallace, Walter Neupert, Werner, Westermann, Wittig, Wolfgang Baumeister, Wong, Wurm, Zick   +77 more
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Adipose-derived Stem Cells Stimulated with -Butylidenephthalide Exhibit Therapeutic Effects in a Mouse Model of Parkinson’s Disease

Cell Transplantation, 2018
Parkinson’s disease (PD) causes motor dysfunction and dopaminergic cell death. Drug treatments can effectively reduce symptoms but often cause unwanted side effects.
Kang Chi, Ru-Huei Fu, Yu-Chuen Huang, Shih-Yin Chen, Ching-Ju Hsu, Shinn-Zong Lin, Chi-Tang Tu, Li-Hsun Chang, Ping-An Wu, Shih-Ping Liu   +9 more
doaj   +1 more source

Aging-Related Changes in the Ultrastructure of Hepatocytes and Cardiomyocytes of Elderly Mice Are Enhanced in ApoE-Deficient Animals

Cells, 2021
Biological aging is associated with various morphological and functional changes, yet the mechanisms of these phenomena remain unclear in many tissues and organs. Hyperlipidemia is among the factors putatively involved in the aging of the liver and heart.
Małgorzata Łysek-Gładysińska, Anna Wieczorek, Artur Jóźwik, Anna Walaszczyk, Karol Jelonek, Grażyna Szczukiewicz-Markowska, Olaf K. Horbańczuk, Monika Pietrowska, Piotr Widłak, Dorota Gabryś   +9 more
doaj   +1 more source

Melanopsin-expressing retinal ganglion cells are resistant to cell injury, but not always [PDF]

, 2017
Melanopsin retinal ganglion cells (mRGCs) are intrinsically photosensitive RGCs deputed to non-image forming functions of the eye such as synchronization of circadian rhythms to light-dark cycle.
Carelli, Valerio, Georg, Birgitte, Ghelli, Anna, Giordano, Carla, Hannibal, Jens, La Morgia, Chiara, Ross Cisneros, Fred N., Sadun, Alfredo A.   +7 more
core   +1 more source

Intracellular position of mitochondria and chloroplasts in bundle sheath and mesophyll cells of C3 grasses in relation to photorespiratory CO2 loss

Plant Production Science, 2016
In C3 plants, photosynthetic efficiency is reduced by photorespiration. A part of CO2 fixed during photosynthesis in chloroplasts is lost from mitochondria during photorespiration by decarboxylation of glycine by glycine decarboxylase (GDC).
Yuto Hatakeyama, Osamu Ueno
doaj   +1 more source

Cryo-electron tomography reveals novel features of a viral RNA replication compartment

eLife, 2017
Positive-strand RNA viruses, the largest genetic class of viruses, include numerous important pathogens such as Zika virus. These viruses replicate their RNA genomes in novel, membrane-bounded mini-organelles, but the organization of viral proteins and ...
Kenneth J Ertel, Desirée Benefield, Daniel Castaño-Diez, Janice G Pennington, Mark Horswill, Johan A den Boon, Marisa S Otegui, Paul Ahlquist   +7 more
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Disturbance of Mitochondrial Dynamics and Mitochondrial Therapies in Atherosclerosis

Life, 2021
Mitochondrial dysfunction is associated with a wide range of chronic human disorders, including atherosclerosis and diabetes mellitus. Mitochondria are dynamic organelles that undergo constant turnover in living cells.
Alexander M. Markin, Viktoria A. Khotina, Xenia G. Zabudskaya, Anastasia I. Bogatyreva, Antonina V. Starodubova, Ekaterina Ivanova, Nikita G. Nikiforov, Alexander N. Orekhov   +7 more
doaj   +1 more source