Results 21 to 30 of about 10,797 (208)
Este es un estudio personal altamente subjetivo sobre la investigación llevada a cabo durante los últimos 50 años que documenta los fenómenos y los mecanismos de la plasticidad del tejido muscular esquelético.
Hans Hoppeler
doaj +1 more source
EFECTO DEL LINALOOL SOBRE LA BIOENERGÉTICA DE MITOCONDRIAS DE HÍGADO DE RATA
Antecedentes: El linalool (2,6-dimetil-2,7-octadien-6-ol) es un monoterpeno presente en más de 200 tipos de plantas, y constituye el componente mayoritario de varios aceites esenciales.
Yenny BUENO-DUARTE +1 more
doaj +1 more source
Remote Mechanisms of Myocardial Protection [PDF]
Introducción: Se ha propuesto que el precondicionamiento isquémico remoto (PCr) reduce el tamaño del infarto a través de laactivación de una vía neuronal parasimpática.
del Mauro, Julieta Sofía +10 more
core +2 more sources
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
The dynamic mitochondria-nuclear redistribution of FKBP51 during the process of adipocyte differentiation is regulated by PKA [PDF]
Los glucocorticoides tienen un papel central en la adipogénesis, por su unión al receptor RG cito-plasmático formando parte de un heterocomplejo también integrado por una inmunofilina (INM) de alto peso molecular, FKBP51 o FKBP52.
Charó, Nancy Lorena +3 more
core +1 more source
Proteostasis of organelles in aging and disease
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi +5 more
wiley +1 more source
Función y biogénesis mitocondrial [PDF]
El objetivo principal de esta tesis se ha centrado en el estudio de las diferencias entre ratas macho y hembra en la morfología, la función y la biogénesis mitocondrial del tejido adiposo marrón (TAM) y del hígado, mediante el análisis de distintas ...
Departament de Biologia Fonamental i Ciències de la Salut +1 more
core
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Effect of Vitamin E on Oocytes Apoptosis in nicotine-treated Mice [PDF]
Objective(s): Cigarette and nicotine enhances embryogenesis, fertility, pregnancy loss and ultrastructure alterations of oocyte. This study was performed to determine the effect of daily supplementation of vitamin E on oocytes apoptosis in nicotine ...
Asadi, E. +2 more
core +1 more source
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source

