Results 31 to 40 of about 2,320 (200)
The FEBS Journal, EarlyView.Human frataxin deficiency causes Friedreich's ataxia, yet how iron‐binding events are communicated across the protein is unclear. Using transfer entropy analysis of molecular dynamics simulations, we identify buried hydrophobic core leucines (LEU136, LEU140) as the source of directional signaling toward the iron‐binding acidic ridge.
Kevser Kübra Kırboğa +1 more
wiley +1 more source
, 2012 La Mitocondria desempeña un papel clave en la activación de la apoptosis en las células de mamíferos. Los miembros de la familia de proteínas de Bcl-2 regulan la liberación de proteínas como Cit c del espacio situado entre la membrana interna y la ...
Ortiz Melón, José Miguel +1 more
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, Volume 600, Issue 19, Page 2876-2898, October 2026.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
FEBS Open Bio, Volume 16, Issue 10, Page 1958-1973, October 2026.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
, 2019 Alignment rate to Nematostella vectensis mitocondria sequence (Version: Nematostella sp. JVK-2006 mitochondrion).
Ann M. Tarrant (7827713) +4 more
core +1 more source
The theory of oxidative stress as a direct cause of cell aging
Medisur, 2018 The loss of functional capacities, aging and death are inherent to all living matter due to metabolism and other factors causing the formation of substances which damage irreversibly cell structure components.
Milagros Lisset León Regal +5 more
doaj +2 more sources
La relevancia de la mitocondria en el cáncer hepático. Revisión sistemática [PDF]
, 2022 Introducción: El cáncer hepático es uno de los tumores más frecuentes a nivel mundial y en el que las terapias actuales no son del todo eficaces, sobre todo en los estadios más avanzados.
Gómez-Reino López, Jorge
core +1 more source
KU80 suppresses endonuclease G activity to preserve genomic integrity
The FEBS Journal, Volume 293, Issue 19, Page 5952-5966, October 2026.Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan +8 more
wiley +1 more source
Estudio de la función de FASTKD3 en la mitocondria [PDF]
, 2017 Tesis Doctoral presentada por Rebeca Torres Merino para optar al grado de Doctora por la Universidad de Valladolid, Facultad de Medicina: Dpto.
Torres-Merino, Rebeca
core +3 more sources
FEBS Open Bio, Volume 16, Issue 9, Page 1801-1812, September 2026.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source