Results 51 to 60 of about 1,602 (210)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, Volume 16, Issue 6, Page 1213-1221, June 2026.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, Volume 16, Issue 6, Page 1150-1165, June 2026.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

La relevancia de la mitocondria en el cáncer hepático. Revisión sistemática [PDF]

, 2022
Introducción: El cáncer hepático es uno de los tumores más frecuentes a nivel mundial y en el que las terapias actuales no son del todo eficaces, sobre todo en los estadios más avanzados.
Gómez-Reino López, Jorge
core  

La obesidad induce cambios en la morfología mitocondrial e incrementa los residuos de nitrotirosina en la placenta humana

Revista Colombiana de Endocrinología, Diabetes y Metabolismo
Contexto: en la obesidad, se observa una disfunción mitocondrial y un aumento del estrés oxidativo, caracterizado por cambios en la estructura de las mitocondrias, acumulación de mutaciones en el ADN mitocondrial y una sobreproducción de especies ...
Karenth Milena Rodriguez Córdoba, María Carolina Pustovrh   +1 more
doaj   +1 more source

Biochemical liver function after partial hepatic resection with or without partial hepatic vascular exclusion Função bioquímica do fígado após ressecção hepática parcial com ou sem exclusão vascular hepática parcial

Acta Cirúrgica Brasileira, 2011
PURPOSE: The aim of the present study was to assess the advantages and disadvantages of liver vascular partial exclusion (LVPE) (liver dysfunction due to ischemia) during liver resection in patients submitted to partial hepatectomy.
Orlando Castro e Silva, Enio David Mente, Ajith Kumar Sankarankutty, Maria Eliza Jordani Souza, Maria Cecília Jordani Gomes, Maria Aparecida Neves Cardoso Picinato, Clarice Fleury Fina, Jorge Resende Lopes Junior   +7 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, Volume 16, Issue 6, Page 1166-1180, June 2026.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

The FEBS Journal, Volume 293, Issue 11, Page 3166-3186, June 2026.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan, Annika Hanraths, Jingchan Xie, Mareike Schallenberg‐Rüdinger, Volker Knoop   +4 more
wiley   +1 more source

El papel de la mitocondria en el dolor de la neuropatía diabética [PDF]

, 2020
La diabetes mellitus es una enfermedad metabólica que afecta a algo más de 300 millones de individuos en el mundo. Entre sus complicaciones, la neuropatía es frecuente y puede afectar nervios sensitivos, motores y autonómicos.
Moreno, Carlos B.::17055366::600, Gutiérrez-Álvarez, Ángela María, Hernández-Beltrán, Natalia   +2 more
core   +1 more source

Efecto del aceite esencial de Eucalyptus citriodora sobre el metabolismo energético mitocondrial

Revista Colombiana de Química, 2014
Con el fin de contribuir al conocimiento de su actividad a nivel celular, se evaluó el mecanismo de acción del aceite esencial de Eucalyptus citriodora (Fam.
Luis Carlos Vesga, Yenny Bueno, Elena Stashenko, Stelia C. Mendez Sánchez   +3 more
doaj   +1 more source

The ribosome‐associated complex regulates cytosolic translation upon mitoprotein‐induced stress

The FEBS Journal, Volume 293, Issue 11, Page 3211-3227, June 2026.
Defects in mitochondrial protein import trigger a stress response. The contribution of translation regulation to such a response is only partially understood. We demonstrate that the deletion of mitochondrial surface proteins (TOM70/TOM71) leads to defects in mitochondrial biogenesis and slow growth.
Jiaxin Qian, Annika Nutz, Katja Hansen, Lea Bertgen, Mirita Franz‐Wachtel, Boris Macek, Johannes M. Herrmann, Doron Rapaport   +7 more
wiley   +1 more source