Results 51 to 60 of about 2,320 (200)

La obesidad induce cambios en la morfología mitocondrial e incrementa los residuos de nitrotirosina en la placenta humana

Revista Colombiana de Endocrinología, Diabetes y Metabolismo
Contexto: en la obesidad, se observa una disfunción mitocondrial y un aumento del estrés oxidativo, caracterizado por cambios en la estructura de las mitocondrias, acumulación de mutaciones en el ADN mitocondrial y una sobreproducción de especies ...
Karenth Milena Rodriguez Córdoba, María Carolina Pustovrh   +1 more
doaj   +1 more source

Biochemical liver function after partial hepatic resection with or without partial hepatic vascular exclusion Função bioquímica do fígado após ressecção hepática parcial com ou sem exclusão vascular hepática parcial

Acta Cirúrgica Brasileira, 2011
PURPOSE: The aim of the present study was to assess the advantages and disadvantages of liver vascular partial exclusion (LVPE) (liver dysfunction due to ischemia) during liver resection in patients submitted to partial hepatectomy.
Orlando Castro e Silva, Enio David Mente, Ajith Kumar Sankarankutty, Maria Eliza Jordani Souza, Maria Cecília Jordani Gomes, Maria Aparecida Neves Cardoso Picinato, Clarice Fleury Fina, Jorge Resende Lopes Junior   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, Volume 600, Issue 16, Page 2262-2282, August 2026.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, Volume 600, Issue 16, Page 2283-2306, August 2026.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Efecto del aceite esencial de Eucalyptus citriodora sobre el metabolismo energético mitocondrial

Revista Colombiana de Química, 2014
Con el fin de contribuir al conocimiento de su actividad a nivel celular, se evaluó el mecanismo de acción del aceite esencial de Eucalyptus citriodora (Fam.
Luis Carlos Vesga, Yenny Bueno, Elena Stashenko, Stelia C. Mendez Sánchez   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, Volume 600, Issue 15, Page 2154-2174, August 2026.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

LAS MITOCONDRIAS EN LA TRANSFORMACIÓN CELULAR DEL EPITELIO MAMARIO [PDF]

Revista chilena de obstetricia y ginecología, 2008
Antecedentes: La adquisición del fenotipo metastático es el resultado de la potente acción generada por on-cogenes transformantes sobre una célula normal los cuales con la consiguiente expresión de oncoproteínas determinan drásticos cambios tanto en la morfología como en los volúmenes de los componentes celulares, generando una célula con diferente ...
openaire   +3 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, Volume 600, Issue 15, Page 2108-2116, August 2026.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Función de la oncoproteína GOLPH3 en la interfase aparato de Golgi-mitocondria [PDF]

, 2023
Doctor en Biología Celular y BiomedicinaDentro de la célula existen diversas formas de comunicación, dentro de las cuales se encuentran el tráfico vesicular o a través de sitios de contactos entre el mismo organelo o con otro organelo diferente. Para que
Meléndez Polanco, Catalina Andrea
core  

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, Volume 600, Issue 16, Page 2219-2225, August 2026.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source