Results 241 to 247 of about 16,238 (247)

Anti-tumour efficacy of mitofusin-2 in urinary bladder carcinoma

Medical Oncology, 2010
Mitochondrial GTPase mitofusin-2 gene (Mfn2) is a novel gene characterised as a cell proliferation inhibitor. Mfn2 protein over-expression, mediated by an adenovirus, has a significant anti-tumour effect in A548 and HT-29 cells. However, there is no report on the effect of Mfn2 on urinary bladder carcinoma (UBCC).
Baiye, Jin, Guanghou, Fu, Hao, Pan, Xiaofei, Cheng, Lin, Zhou, Jia, Lv, Geming, Chen, Shusen, Zheng   +7 more
openaire   +2 more sources

Mitofusin 2 regulates actin cytoskeleton and cell migration

2022
Zebrafish (Danio rerio) is a well-established model to study neutrophil biology. However, a lack of standard tissue-specific knockdown or knockout technique in the zebrafish field has limited the power of this model organism when studying developmental essential genes, such as those related to mitochondrial function.
openaire   +1 more source

Overexpression of mitofusin 2 inhibits reactive astrogliosis proliferation in vitro

Neuroscience Letters, 2014
Astrocytes become activated in response to central nervous system (CNS) injury, and excessive astrogliosis is considered an impediment to axonal regeneration by forming glial scar. Mitofusin 2 (Mfn2), a key protein in mitochondrial network, has been reported to negatively regulate cell proliferation.
Tao, Liu, Chen-chen, Xue, Yu-long, Shi, Xiang-jun, Bai, Zhan-fei, Li, Cheng-la, Yi   +5 more
openaire   +2 more sources

Research Progress of Mitofusin-2*

PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2010
Guang-Ju ZHAO, Zhong-Qiu LU, Yong-Ming YAO   +2 more
openaire   +1 more source

Regulation of mitofusin-2 expression in skeletal muscle.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2009
Fusion and fission of mitochondria regulate their morphology and distribution. Mitofusin-2 (Mfn2) is a mitochondrial protein involved in such fusion. Recent observations indicate that Mfn2 is a multifunctional protein that participates in cell proliferation and metabolism and that it is required for normal endoplasmic reticulum morphology.
openaire   +1 more source

Age‐related muscle atrophy? Mitofusin 2 the rescue

Acta Physiologica
Agustina Creus, David Sebastián
openaire   +2 more sources

[Advances in structure and function of mitofusin 2].

Sheng li ke xue jin zhan [Progress in physiology], 2018
Zuo, Ying, Zhongqiu, Lu, Yongming, Yao
openaire   +1 more source