Results 71 to 80 of about 229,005 (218)

Vasopressin inhibits mitogen-activated protein kinases and activated protein-1 in macrophages

Acta Anaesthesiologica Taiwanica, 2015
We have previously shown that vasopressin could inhibit the upregulation of inflammatory mediators. Expression of inflammatory mediators is tightly regulated by the upstream transcriptional pathway mitogen-activated protein kinases (MAPKs) and activated protein-1 (AP-1). In this study, we elucidated whether vasopressin could inhibit the upregulation of
Chen, Yu-Long, Chang, Ya-Ying, Kao, Ming-Chang, Huang, Chun-Jen   +3 more
openaire   +2 more sources

Evaluation of both expression and serum protein levels of caspase-8 and mitogen-activated protein kinase 1 genes in patients with different severities of COVID-19 infection. [PDF]

Mol Biol Rep, 2023
Acat M, Yıldız Gülhan P, Eröz R, Ertınmaz Özkan A, Koca O, Çınar C.   +5 more
europepmc   +1 more source

In Silico Design of E3 Ubiquitin-Protein Ligase NEDD4-1 Inhibitors: An Alternative Approach for Targeting the MAPK Pathway in Cancer Therapy

Proceedings, 2019
Among all the several targets in common use in the antitumor therapies, the pharmacologicinhibition of the MAPK (Mitogen Activated Protein Kinase) pathway represents an efficienttherapeutic approach [1]. [...]
Davide Pirolli, Benedetta Righino, Beatrice Tropea, Fiorella Gurrieri, Eugenio Sangiorgi, Maria Cristina De Rosa   +5 more
doaj   +1 more source

[Retracted] MicroRNA‑454 inhibits the malignant biological behaviours of gastric cancer cells by directly targeting mitogen‑activated protein kinase 1. [PDF]

Oncol Rep, 2022
Wang X, Liu B, Wen F, Song Y.
europepmc   +1 more source

Rapeseed (Brassica napus) Mitogen-Activated Protein Kinase 1 Enhances Shading Tolerance by Regulating the Photosynthesis Capability of Photosystem II. [PDF]

Front Plant Sci, 2022
Wang Z, Liu M, Yao M, Zhang X, Qu C, Du H, Lu K, Li J, Wei L, Liang Y.   +9 more
europepmc   +1 more source

Knockdown of circ_0001679 alleviates lipopolysaccharide-induced MLE-12 lung cell injury by regulating the miR-338-3p/ mitogen-activated protein kinase 1 axis. [PDF]

Bioengineered, 2022
Lu S, Wu X, Xin S, Zhang J, Lin H, Miao Y, Li Y.   +6 more
europepmc   +1 more source

Extracellularly Regulated Kinases 1/2 (p44/42 Mitogen-Activated Protein Kinases) Phosphorylate Synapsin I and Regulate Insulin Secretion in the MIN6 β-Cell Line and Islets of Langerhans [PDF]

, 2004
Christine Longuet, Christophe Broca, Safia Costes, El Habib Hani, D. Bataille, Stéphane Dalle   +5 more
openalex   +1 more source

Supplementary Table 1 from Epigenetically Controlled Fibroblast Growth Factor Receptor 2 Signaling Imposes on the RAS/BRAF/Mitogen-Activated Protein Kinase Pathway to Modulate Thyroid Cancer Progression

, 2023
Tetsuo Kondo, Lei Zheng, Wei Liu, Junichi Kurebayashi, L. Sylvia, Shereen Ezzat   +5 more
openalex   +1 more source

Cetylpyridinium chloride triggers paraptosis to suppress pancreatic tumor growth via the ERN1-MAP3K5-p38 pathway

iScience
Summary: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive solid malignancy with low 5-year survival and limited treatment options. We conducted an unbiased screening using FDA-approved drug and demonstrated that cetylpyridinium chloride ...
Hu Tang, Fangquan Chen, Wanli Gao, Xiutao Cai, Zhi Lin, Rui Kang, Daolin Tang, Jiao Liu   +7 more
doaj   +1 more source

CircRNA casein kinase 1 gamma 1 (circ-CSNK1G1) plays carcinogenic effects in thyroid cancer by acting as miR-149-5p sponge and relieving the suppression of miR-149-5p on mitogen-activated protein kinase 1 (MAPK1). [PDF]

J Clin Lab Anal, 2022
Chen H, Li Q, Yi R, Li B, Xiong D, Peng H.   +5 more
europepmc   +1 more source