Results 81 to 90 of about 229,005 (218)

Activation of Discoidin Domain Receptor 1 Facilitates the Maturation of Human Monocyte-Derived Dendritic Cells Through the TNF Receptor Associated Factor 6/TGF-β-Activated Protein Kinase 1 Binding Protein 1β/p38α Mitogen-Activated Protein Kinase Signaling Cascade [PDF]

, 2003
Wataru Matsuyama, Michel Faure, Teizo Yoshimura   +2 more
openalex   +1 more source

Supplementary Figure S1 from Multicenter Phase I Trial of the Mitogen-Activated Protein Kinase 1/2 Inhibitor BAY 86-9766 in Patients with Advanced Cancer

, 2023
Colin D. Weekes, Daniel D. Von Hoff, Alex A. Adjei, Diane P. Leffingwell, S. Gail Eckhardt, Lia Gore, Karl D. Lewis, Glen J. Weiss, Ramesh K. Ramanathan, Grace K. Dy, Wen Wang, Beth Sheedy, Cory Iverson, Jeffrey N. Miner, Zancong Shen, Li‐Tain Yeh, Ronald L. Dubowy, Michael Jeffers, Prabhu Rajagopalan, Neil J. Clendeninn   +19 more
openalex   +1 more source

Short-term low-protein diet during pregnancy alters islet area and protein content of phosphatidylinositol 3-kinase pathway in rats

Anais da Academia Brasileira de Ciências, 2015
The phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways mediate β cell growth, proliferation, survival and death. We investigated whether protein restriction during pregnancy alters islet morphometry or the expression and ...
CRISTIANA S.B. SALVATIERRA, SÍLVIA R.L. REIS, ANA F.M. PESSOA, LETÍCIA M.I. DE SOUZA, LUIZ F. STOPPIGLIA, ROBERTO V. VELOSO, MARISE A.B. REIS, EVERARDO M. CARNEIRO, ANTONIO C. BOSCHERO, EDSON M. COLODEL, VANESSA C. ARANTES, MÁRCIA Q. LATORRACA   +11 more
doaj   +1 more source

Phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase regulate induction of Mcl-1 and survival in glucocorticoid-treated human neutrophils [PDF]

, 2007
Arash S. Saffar, Stéphane Dragon, Peyman Ezzati, Lianyu Shan, Abdelilah S. Gounni   +4 more
openalex   +1 more source

Role of Pentacyclic Triterpenoids in Chemoprevention and Anticancer Treatment: An Overview on Targets and Underling Mechanisms

Journal of Pharmacopuncture, 2019
DNA: Deoxyribonucleic acid, BRCA1: Breast cancer gene 1, BRCA2: Breast cancer gene 2,WHO: World Health Organization, Nrf2: Nuclear factor erythroid 2 [NF-E2]-related factor 2 , NF-κB: Nuclear factor kappa-light-chain-enhancer of activated B cells, MDR ...
Mahavir H. Ghante, Prasad G. Jamkhande
doaj   +1 more source

LncRNA KCNQ1OT1 (potassium voltage-gated channel subfamily Q member 1 opposite strand/antisense transcript 1) aggravates acute kidney injury by activating p38/NF-κB pathway via miR-212-3p/MAPK1 (mitogen-activated protein kinase 1) axis in sepsis. [PDF]

Bioengineered, 2021
Wang H, Mou H, Xu X, Liu C, Zhou G, Gao B.   +5 more
europepmc   +1 more source

Human T-cell lymphotropic virus type 1 (HTLV-1) grip on T-cells: investigating the viral tapestry of activation

Infectious Agents and Cancer
Introduction Human T-cell Lymphotropic virus type 1 (HTLV-1) belongs to retroviridae which is connected to two major diseases, including HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and Adult T-cell leukemia/lymphoma (ATLL).
Arash Letafati, Atefeh Bahavar, Alijan Tabarraei, Mehdi Norouzi, Abdollah Amiri, Sayed-Hamidreza Mozhgani   +5 more
doaj   +1 more source

Korean Red Ginseng mitigates spinal demyelination in a model of acute multiple sclerosis by downregulating p38 mitogen-activated protein kinase and nuclear factor-κB signaling pathways

Journal of Ginseng Research, 2018
Background: The potential therapeutic values of Korean Red Ginseng extract (KRGE) in autoimmune disorders of nervous system have not been fully investigated.
Min Jung Lee, Byung Joon Chang, Seikwan Oh, Seung-Yeol Nah, Ik-Hyun Cho   +4 more
doaj   +1 more source

Retracted: microRNA‐542‐5p protects against acute lung injury in mice with severe acute pancreatitis by suppressing the mitogen‐activated protein kinase signaling pathway through the negative regulation of P21‐activated kinase 1 [PDF]

, 2018
Xing‐Mao Wu, Kaiqiang Ji, Haiyuan Wang, Zhao Yang, Jia Jia, Xiaopeng Gao, Bin Zang   +6 more
openalex   +1 more source

Insulin-Like Growth Factor-Binding Protein 1 Stimulates Human Trophoblast Migration by Signaling through α5β1 Integrin via Mitogen-Activated Protein Kinase Pathway¹ [PDF]

, 2001
Louise M. Gleeson, Chandan Chakraborty, Timothy McKinnon, Peeyush K. Lala   +3 more
openalex   +1 more source