Journal of the Chinese Chemical Society, EarlyView.Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley +1 more source
Regulation of Cell Proliferation and Migration by Extracellular Phosphatidic Acid. [PDF]
BiomedicinesGomez-Larrauri A +4 more
europepmc +1 more source
Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract
Journal of Chemical Technology &Biotechnology, EarlyView.Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass +2 more
wiley +1 more source
Anatomical Atlas of Kinase Responsiveness to Weight Gain: Adipose Depot Reprogramming in Diet-Induced Adiposity. [PDF]
MetabolitesLee WH +5 more
europepmc +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen +2 more
wiley +1 more source
CAFs and Endocrine Therapy Resistance in Hormone Receptor-Positive Breast Cancer. [PDF]
Int J Mol SciSofianidi AA, Stafyla VK, Zagouri F.
europepmc +1 more source
Neutrophil Elastase and Interleukin 17 Expressed in the Pig Colon during Brachyspira hyodysenteriae Infection Synergistically with the Pathogen Induce Increased Mucus Transport Speed and Production via Mitogen-Activated Protein Kinase 3. [PDF]
Infect Immun, 2017 Quintana-Hayashi MP +7 more
europepmc +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuronal loss driven by oxidative stress and inflammation. Quercetin, a dietary flavonoid with established antioxidant and anti‐inflammatory properties, has emerged as a potential neuroprotective agent.
In Ho Cho +6 more
wiley +1 more source
Pyrrolizidine Alkaloid-Induced Hepatotoxicity: A Narrative Review on Molecular Mechanisms and Detoxification Strategies. [PDF]
Antioxidants (Basel)Fang Y, Zhang X, Dai C, Hao Z.
europepmc +1 more source
Nail Toxicities Associated With Anticancer Therapies in Children
JEADV Clinical Practice, EarlyView.ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley +1 more source