INFLUENCE OF BIOLOGICAL METHYLATION ON THE BIOSYNTHESIS OF MITOMYCIN A [PDF]
E. J. Kirsch, J. D. KORSHALLA
openalex +1 more source
Distinct DNA repair pathways involving RecA and nonhomologous end joining in Mycobacterium smegmatis [PDF]
Mycobacterium smegmatis was used to study the relationship between DNA repair processes involving RecA and nonhomologous end joining (NHEJ). The effect of gene deletions in recA and/or in two genes involved in NHEJ (ku and ligD) was tested on the ability
Anna Brzostek+39 more
core +1 more source
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert+10 more
wiley +1 more source
Effects of Mitomycin C and Thymidine Deprivation on Lysogenic and Sensitive Strains of Bacillus megaterium [PDF]
W. F. Maisch, J. T. Wachsman
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Tuberculosis vaccine strain _Mycobacterium bovis_ BCG Russia is a natural _recA_ mutant [PDF]
The current tuberculosis vaccine is a live vaccine derived from _Mycobacterium bovis_ and attenuated by serial _in vitro_ passaging. All vaccine substrains in use stem from one source, strain Bacille Calmette-Guérin.
Erik C. Boettger+2 more
core +1 more source
DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes [PDF]
There is some interest in how mammalian oocytes respond to different types of DNA damage because of the increasing expectation of fertility preservation in women undergoing chemotherapy.
Julie A. Merriman+4 more
core +3 more sources
Mitomycin-C Use in Ophthalmology
Mitomycin-C is a chemotherapeutic drug that acts by inhibiting DNA synthesis. Its use and application in ophthalmology has been increasing in recent years because of its mandatory effects on wound healing.
Parul Singh
semanticscholar +1 more source
Abstract Purpose To assess the prognosis and determinants of survival after orbital exenteration in patients with conjunctival melanoma (CoM). Methods In a retrospective study, 27 consecutive patients who underwent exenteration for CoM from 2001 to 2023 were included.
David Chetroiu+7 more
wiley +1 more source
MUTAGENIC EFFECT OF MITOMYCIN C ON MYCOBACTERIUM AND ITS COMBINED EFFECT WITH ULTRAVIOLET IRRADIATION [PDF]
S Tsukamura, Michio Tsukamura
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A study of oral metformin for the intravesical treatment of non‐muscle‐invasive bladder cancer
Objectives To evaluate the effect of metformin on non‐muscle‐invasive bladder cancer (NMIBC) marker lesions. Patients and methods A phase II, open‐label, multicentre, marker lesion trial using oral metformin in patients with primary or recurrent, multiple, low‐grade Ta‐T1 NMIBC was conducted. After transurethral resection for histological confirmation,
Jons W. van Hattum+12 more
wiley +1 more source