Results 131 to 140 of about 100,295 (288)
Perturbation Detection Through Modeling of Gene Expression on a Latent Biological Pathway Network: A Bayesian hierarchical approach [PDF]
, 2014 Cellular response to a perturbation is the result of a dynamic system of biological variables linked in a complex network. A major challenge in drug and disease studies is identifying the key factors of a biological network that are essential in ...
Carvalho, Luis +3 more
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Advanced Science, Volume 13, Issue 7, 3 February 2026.In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang +12 more
wiley +1 more source
Advanced Science, Volume 13, Issue 7, 3 February 2026.In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu +10 more
wiley +1 more source
Phase II trial of irinotecan, cisplatin and mitomycin for relapsed small cell lung cancer [PDF]
, 2007 Dean A. Fennell +7 more
openalex +1 more source
Bioelectromagnetics, Volume 47, Issue 2, February 2026.ABSTRACT Both everyday electrical devices and high voltage transmission lines produce electric and magnetic fields with a frequency of 50 Hz in Europe and most other countries. Although several studies have already been investigating the effects of extremely low frequency magnetic field (ELF‐MF) exposure on biological material, this topic is still ...
Vivian Meyer +3 more
wiley +1 more source
Validation of an HPLC-MS/MS and Wipe Procedure for Mitomycin C Contamination [PDF]
, 2014 Clayton B’Hymer +3 more
openalex +1 more source
Adverse Renal Outcomes in Patients With Mesothelioma—A Territory‐Wide Real‐World Data
Cancer Medicine, Volume 15, Issue 2, February 2026.ABSTRACT Introduction Advances in mesothelioma management have translated into longer patient survival and different treatment‐related side effects including nephrotoxicity. The risk of developing adverse renal outcomes in patients with mesothelioma and associated risk factors remains undefined.
Wang Chun Kwok +3 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Radio‐induced dermatitis, a frequent adverse effect of radiation therapy, is particularly prevalent in patients treated for anal margin carcinoma. It may present with varying severity, causing significant pain and impairment of daily mobility, influenced by both patient‐related factors and treatment regimens.
Michèle Pelletier‐Aouizerate +1 more
wiley +1 more source
Topical application of mitomycin-C in corrosive esophageal strictures
Journal of Indian Association of Pediatric Surgeons, 2005 Introduction: Corrosive ingestion is the major cause of esophageal stricture in our country. Mitomycin-C, an anthracycline derived from Streptomyces caespitosus, has both antineoplastic and antiproliferative properties. Use of mitomycin-C have been well
Kumar Arun, Bhatnagar V
doaj
The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands. [PDF]
, 1997 One hypothesis seeking to explain the signaling and biological properties of T cell receptor for antigen (TCR) partial agonists and antagonists is the coreceptor density/kinetic model, which proposes that the pharmacologic behavior of a TCR ligand is ...
Bluestone, JA +4 more
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