Results 141 to 150 of about 19,645,635 (339)

Mitomycin-C Use in Ophthalmology

open access: yes, 2013
Mitomycin-C is a chemotherapeutic drug that acts by inhibiting DNA synthesis. Its use and application in ophthalmology has been increasing in recent years because of its mandatory effects on wound healing.
Parul Singh
semanticscholar   +1 more source

Minimally Invasive Glaucoma Surgery: Is It Here to Stay?

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT The advent of minimally invasive glaucoma surgery (MIGS) has expanded the treatment options available for glaucoma by providing options for reducing intraocular pressure without the serious complication profile associated with incisional glaucoma surgery.
Neeranjali Jain, Jennifer C. Fan Gaskin
wiley   +1 more source

Inhibitory Effects of 3′,4′‐Dihydroxyflavonol in a Rabbit Model of Minimally Invasive Bleb Surgery With PreserFlo MicroShunt

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The success of minimally invasive bleb surgery (MIBS) such as the PreserFlo MicroShunt (PFMS) is limited by post‐operative bleb fibrosis. Current clinical practice prescribes the use of off‐label cytotoxic antimetabolites such as Mitomycin C (MMC) as antifibrotic therapy.
Zoe Pasvanis   +3 more
wiley   +1 more source

Successful treatment of post-intubation tracheal stenosis with balloon dilation, argon plasma coagulation, electrocautery and application of mitomycin C

open access: yesSouthwest Respiratory and Critical Care Chronicles, 2015
Tracheal stenosis is an uncommon but known complication of endotracheal intubation and tracheostomy. Surgery is currently the definitive treatment for tracheal stenosis but carries a significantly higher risk for adverse events as it often involves ...
Audra Fuller   +3 more
doaj  

Comprehensive Update on Implants in Patients With Head and Neck Cancer (2021–2024): Systematic Review and Meta‐Analysis of the Impact of Radiotherapy and Chemotherapy on Implant Survival

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This study aimed to investigate implant outcomes in patients with head and neck cancer undergoing radiotherapy or chemotherapy by incorporating the latest research findings. Methods The present review was conducted to update the focused question: What is the survival rate of implants placed in patients with head and neck cancer ...
Shengchi Fan   +5 more
wiley   +1 more source

Hypertranscription of rDNA Responsible for Nucleolar Remodelling is a Doorman for Acquiring Pluripotency

open access: yesCell Proliferation, EarlyView.
Active nucleoli have the capability to release perinuclear heterochromatin, which is a novel event of iPSC reprogramming. ABSTRACT Ribosome biogenesis occurs within the nucleolus, with the initial step being the transcription of ribosomal DNA (rDNA). Although rDNA transcription is limited in somatic cells, it is more active in stem cells. Nevertheless,
Yuchen Sun   +7 more
wiley   +1 more source

NSun2‐Mediated tsRNAs Alleviate Liver Fibrosis via FAK Dephosphorylation

open access: yesCell Proliferation, EarlyView.
NSun2 deficiency inhibited sinusoidal capillarization, alleviating liver fibrosis. Reduced NSun2 expression led to alterations in the functional tsRNAs tRF‐1‐S25 and tRF‐5‐V31, which regulate sinusoidal capillarization by targeting key proteins, including DUSP1 and FAK – crucial clinical targets – offering a novel RNA‐based therapeutic approach for ...
Pengcheng Li   +14 more
wiley   +1 more source

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