Tumor innervation in cervical cancer: Prognostic insights from myelin‐associated risk signatures
Analyses of publicly available cancer genomics data with respect to Schwann cells relevant signatures can provide important insights. Chen et al. show that intratumoral innervation promotes cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) metastasis. Higher nerve density impairs immune cell infiltration, reduces the expression of
Guoqiang Chen+9 more
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IMMUNOSUPPRESSIVE ACTIVITY OF MITOMYCIN C
G Sakauchi, Charles W. Dewitt
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Interstitial fibrosis in a patient treated with 5-fluorouracil and mitomycin C. [PDF]
J W L Fielding+3 more
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Mutations in AcrR and RNA Polymerase Confer High-Level Resistance to Psoralen-UVA Irradiation. [PDF]
Worley TK+6 more
europepmc +1 more source
Bacterial Species in Engineered Living Materials: Strategies and Future Directions
Bacterial ELMs can be derived from two sources: natural biofilms and hybrid living materials. In natural biofilms, the production of ELMs involves the genetic engineering of bacteria to manipulate the biofilm matrix components for desired material properties.
Hu Wang+3 more
wiley +1 more source
Prophylactic surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC CO2) versus standard surgery in colorectal carcinoma at high risk of peritoneal carcinomatosis: short-term and long-term outcomes from the CHECK study - protocol for a randomised, multicentre, phase 3 trial. [PDF]
Pacelli F+11 more
europepmc +1 more source
ABSTRACT Recent evidence suggests that atorvastatin exacerbates paclitaxel neurotoxicity via P‐glycoprotein inhibition. We used a translational approach to investigate if atorvastatin or simvastatin exacerbates (i) paclitaxel neurotoxicity in human sensory neurons and (ii) paclitaxel‐induced peripheral neuropathy (PIPN) in cancer patients.
Emma Simonsen+7 more
wiley +1 more source
Abstract The EFSA Panel on Food Contact Materials assessed the safety of N,N′‐(2‐(4‐(2‐aminobenzamido)butyl)pentane‐1,5‐diyl)bis(2‐aminobenzamide) to be used at up to 650 mg/kg in polyethylene terephthalate (PET) to scavenge acetaldehyde (AA). Final articles are intended for contact with aqueous, acidic and low‐alcoholic beverages for long‐term storage
EFSA Panel on Food Contact Materials (FCM)+18 more
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Transcription of the Col E1 genome in colicinogenic E. coli strains during induction with mitomycin C [PDF]
Wilfried Schieß, Werner Goebel
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