Results 41 to 50 of about 13,073 (205)

NSun2‐Mediated tsRNAs Alleviate Liver Fibrosis via FAK Dephosphorylation

Cell Proliferation, EarlyView.
NSun2 deficiency inhibited sinusoidal capillarization, alleviating liver fibrosis. Reduced NSun2 expression led to alterations in the functional tsRNAs tRF‐1‐S25 and tRF‐5‐V31, which regulate sinusoidal capillarization by targeting key proteins, including DUSP1 and FAK – crucial clinical targets – offering a novel RNA‐based therapeutic approach for ...
Pengcheng Li, Sunyang Ying, Yu Zou, Xin Wang, Runxue Zhang, Cheng Huang, Moyu Dai, Kai Xu, Guihai Feng, Xin Li, Haiping Jiang, Zhikun Li, Ying Zhang, Wei Li, Qi Zhou   +14 more
wiley   +1 more source

Mitomycin C-sensitive mutant of Eschericha coli K-12 [PDF]

, 1968
Y Imae
openalex   +1 more source

Sex‐related changes in lactate dehydrogenase A expression differently impact the immune response in melanoma

The FEBS Journal, EarlyView.
Here, we explore a differential sex‐related metabolic‐immune relationship in melanoma. Melanoma tumours in male patients exhibit a higher LDH‐A‐driven production of lactate compared to their female counterparts. In turn, lactate acts as an immunosuppressive molecule, promoting pro‐tumoural Treg cells and suppressing anti‐tumoural CD8+ T‐cell activity ...
Marta Iozzo, Giuseppina Comito, Luigi Ippolito, Giada Sandrini, Elisa Pardella, Erica Pranzini, Mariaelena Capone, Gabriele Madonna, Paolo Antonio Ascierto, Paola Chiarugi, Elisa Giannoni   +10 more
wiley   +1 more source

Effects of Mitomycin C on Macromolecular Synthesis in Escherichia coli [PDF]

, 1967
Hiromi Suzuki, Wendell W. Kilgore
openalex   +1 more source

Differential Risk Factors for Early Intravesical Recurrence After Radical Nephroureterectomy for Upper Urinary Tract Carcinoma According to the History of Non‐Muscle Invasive Bladder Cancer

International Journal of Urology, Volume 32, Issue 5, Page 567-574, May 2025.
ABSTRACT Objectives To evaluate the preoperative risk factors for early intravesical recurrence after radical nephroureterectomy (RNU) in patients with upper urinary tract carcinoma (UTUC) according to the history of non‐muscle invasive bladder cancer (NMIBC).
Tetsuya Shindo, Yohei Ueki, Ippei Muranaka, Genki Kobayashi, Shintaro Miyamoto, Yasuharu Kunishima, Shunsuke Sato, Manabu Okada, Shuichi Kato, Ryuichi Kato, Hideki Adachi, Masanori Matsukawa, Akio Takayanagi, Naoki Ito, Atsushi Wanifuchi, Takeshi Maehana, Yuki Kyoda, Kohei Hashimoto, Ko Kobayashi, Toshiaki Tanaka, Naoya Masumori   +20 more
wiley   +1 more source

INHIBITION OF MICROBIAL GROWTH AND SEPARATION BYd-SERINE, VANCOMYCIN, AND MITOMYCIN C [PDF]

, 1963
Norman N. Durham
openalex   +1 more source

Biosynthesis of DNA-Alkylating Antitumor Natural Products. [PDF]

Molecules, 2022
Nie QY, Hu Y, Hou XF, Tang GL.
europepmc   +1 more source

Selectivity and anti‐tumor immune elevation by vascular‐targeted photodynamic therapy of mouse orthotopic bladder cancer model

Photochemistry and Photobiology, EarlyView.
Vascular‐targeted photodynamic therapy (VTP) using the photosensitizer WST11 is a non‐surgical tumor ablation approach. Light activation of WST11 leads to excessive generation of reactive oxygen species, which causes tumor vascular arrest, followed by destruction of tumor blood vessels and tumor necrosis.
Jie Chen, Natalia Kudinova, Rebecca Dubrovsky, Jasmine Thomas, Karan Nagar, Lucas Nogueira, Avigdor Scherz, Kwanghee Kim, Jonathan Coleman   +8 more
wiley   +1 more source

The efficacy and safety of mitomycin C intra urethral injection to prevent recurrent urethral stricture: A systematic review and meta-analysis. [PDF]

Ann Med Surg (Lond), 2022
Pranata FH, Hidayatullah F, Kloping YP, Rahman ZA, Rizaldi F, Soebadi DM.   +5 more
europepmc   +1 more source

Assessing the efficacy and safety of sequential intravesical gemcitabine and docetaxel – does time from transurethral resection of bladder tumour to induction matter?

BJU International, EarlyView.
Ian M. McElree, Grant M. Henning, Ryan L. Steinberg, Helen Y. Hougen, Sarah L. Mott, Michael A. O’Donnell, Vignesh T. Packiam   +6 more
wiley   +1 more source