Results 71 to 80 of about 13,073 (205)

A gold(i)-catalysed approach towards harmalidine an elusive alkaloid from Peganum harmala. [PDF]

RSC Adv, 2022
Miaskiewicz S, Weibel JM, Pale P, Blanc A.   +3 more
europepmc   +1 more source

Role of radiotherapy in surgical approaches to pancreatic cancer treatment: A narrative review

Annals of Gastroenterological Surgery, Volume 9, Issue 3, Page 418-428, May 2025.
This review explores the role of radiotherapy (RT) in the multidisciplinary treatment of pancreatic ductal adenocarcinoma (PDAC), focusing on its integration with surgical strategies to improve resectability, local control, and survival outcomes while addressing potential challenges and future research directions.
Satoshi Yasuda, Minako Nagai, Kota Nakamura, Yasuko Matsuo, Masayuki Sho   +4 more
wiley   +1 more source

Bulky Adducts in Clustered DNA Lesions: Causes of Resistance to the NER System. [PDF]

Acta Naturae, 2022
Naumenko NV, Petruseva IO, Lavrik OI.
europepmc   +1 more source

Outcomes in BCG failure: Outcome from a single centre UK experience

BJUI Compass, Volume 6, Issue 5, May 2025.
Abstract Objective To describe real‐world outcomes of patients with BCG failure undergoing bladder‐sparing treatments (BSTs) vs radical cystectomy in the UK. Patients and Methods A single institution audit was conducted at a tertiary bladder cancer referral service (UCLH, London, UK). Patients with BCG failure treated between January 2017 and September
Elizabeth Day, Rachel Aquilina, Lazaros Tzelves, Ashwin Sridhar, Anthony Ta, John Kelly, Bernadett Szabados   +6 more
wiley   +1 more source

Synthesis of Oligonucleotides containing the cis-Interstrand Crosslink Produced by Mitomycins in their Reaction with DNA. [PDF]

Chemistry, 2020
Aguilar W, Zacarias O, Romaine M, Proni G, Petrovic AG, Abzalimov R, Paz MM, Champeil E.   +7 more
europepmc   +1 more source

Streptomyces rugosispiralis sp. nov., a Novel Actinobacterium Isolated from Peat Swamp Forest Soil That Produces Ansamycin Derivatives and Nocardamines. [PDF]

Antibiotics (Basel), 2023
Weeraphan T, Supong K, Sripreechasak P, Jutakanoke R, Kowinthanaphat S, Tanasupawat S, Pittayakhajonwut P, Phongsopitanun W.   +7 more
europepmc   +1 more source

Reactive Oxygen Species: From Tumorigenesis to Therapeutic Strategies in Cancer

Cancer Medicine, Volume 14, Issue 10, May 2025.
ABSTRACT Background Reactive oxygen species (ROS), a class of highly reactive molecules, are closely linked to the pathogenesis of various cancers. While ROS primarily originate from normal cellular processes, external stimuli can also contribute to their production. Cancer cells typically exhibit elevated ROS levels due to disrupted redox homeostasis,
Iqra Attique, Zahra Haider, Maha Khan, Samina Hassan, Mohamed Mohamed Soliman, Wisam Nabeel Ibrahim, Sumaira Anjum   +6 more
wiley   +1 more source

Exploring the Relationships between Structure and Antimicrobial Potency of Quinolinequinones. [PDF]

Antibiotics (Basel), 2022
Mataracı-Kara E, Bayrak N, Yıldız M, Yıldırım H, TuYuN AF.   +4 more
europepmc   +1 more source

Screening of candidate analgesics using a patient‐derived human iPSC model of nociception identifies putative compounds for therapeutic treatment

Clinical and Translational Medicine, Volume 15, Issue 5, May 2025.
In this study, Thornton and colleagues utilised an induced pluripotent stem cell (iPSC)‐based model of inherited erythromelalgia (IEM) to screen a library of 295 small molecules in search of potential pain‐modulating compounds. Their screening identified four compounds that significantly reduced spontaneous firing in iPSC‐derived nociceptor‐like cells,
Jack R. Thornton, Alberto Capurro, Sally Harwood, Thomas C Henderson, Adrienne Unsworth, Franziska Görtler, Sushma Nagaraja‐Grellscheid, Vsevolod Telezhkin, Majlinda Lako, Evelyne Sernagor, Lyle Armstrong   +10 more
wiley   +1 more source

Activity of Mitomycin C, Other Antibiotics, and Serum Against Lysogenic Bacteria

, 1966
Louis H. Muschel, Karen Schmoker
openalex   +1 more source