Results 71 to 80 of about 1,470 (180)

Far‐infrared irradiation attenuates platelet‐derived growth factor‐stimulated vascular smooth muscle cell migration through protein phosphatase 2A‐mediated Akt inhibition

open access: yesPhotochemistry and Photobiology, EarlyView.
FIR irradiation enhances the physical association between Akt and PP2Ac in VSMCs, independent of the hyperthermal effect of FIR rays. The increased binding between Akt and PP2Ac induced by FIR irradiation facilitates the dephosphorylation of Akt at Ser473.
Na‐Young Lee   +5 more
wiley   +1 more source

Exploration into the Cellular Effects of Aziridinomitosenes [PDF]

open access: yes, 2014
Aziridinomitosenes (AZMs) are organic compounds structurally related to the mitomycins, a class of anti-tumor agents and antibiotics. The cytotoxicity of the mitomycins is correlated to their ability to covalently link complimentary strands of DNA ...
Mallory, Christopher M.
core   +1 more source

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

open access: yesPhotochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore   +6 more
wiley   +1 more source

An aryl radical cyclisation approach to highly substituted oxindoles related to mitomycins

open access: yesARKIVOC, 2000
Keith Jones, John M. D. Storey
doaj   +1 more source

Accidental Extravasation of Mitomycin C into the Subcutaneous Tissue. [PDF]

open access: yesHCA Healthc J Med, 2023
Chung J   +4 more
europepmc   +1 more source

Vision outcomes in dogs with primary glaucoma surgically treated with lensectomy and endolaser cyclophotocoagulation after an Ahmed valve gonioimplantation failure

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 207-217, March 2025.
Abstract Objective The aim of this study was to retrospectively evaluate vision outcomes of dogs with primary angle closure glaucoma (PACG) that underwent Ahmed valve gonioimplantation (AVG) followed by lensectomy and endolaser cyclophotocoagulation (ECP) with or without bleb resection after AVG failure.
Bactelius Turicea   +3 more
wiley   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi   +6 more
wiley   +1 more source

Radical cyclisations onto imidazoles [PDF]

open access: yes, 1997
This thesis describes the development of new pathways towards the synthesis of novel antimicrobial (and anticancer) agents. Two synthetic protocols based on free radical chemistry are studied, which are used to access polycyclic heterocyclic compounds of
Fawaz Aldabbagh (1672639)
core  

Immunosuppression and Surgery‐Free Interval in Granulomatosis With Polyangiitis Airway Stenosis

open access: yesThe Laryngoscope, Volume 136, Issue 4, Page 1858-1865, April 2026.
Subglottic and tracheal stenosis are severe manifestations of granulomatosis with polyangiitis (GPA) that often require both endoscopic intervention and systemic immunosuppression. Rituximab may help stabilize GPA‐related airway disease by prolonging the interval between endoscopic procedures and delaying relapse.
Sydney J. Torres   +6 more
wiley   +1 more source

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