Results 81 to 90 of about 13,879 (218)

Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang   +12 more
wiley   +1 more source

Phase II trial of irinotecan, cisplatin and mitomycin for relapsed small cell lung cancer [PDF]

open access: bronze, 2007
Dean A. Fennell   +7 more
openalex   +1 more source

An aryl radical cyclisation approach to highly substituted oxindoles related to mitomycins

open access: yesARKIVOC, 2000
Keith Jones, John M. D. Storey
doaj   +1 more source

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu   +10 more
wiley   +1 more source

Validation of an HPLC-MS/MS and Wipe Procedure for Mitomycin C Contamination [PDF]

open access: bronze, 2014
Clayton B’Hymer   +3 more
openalex   +1 more source

Exploration into the Cellular Effects of Aziridinomitosenes [PDF]

open access: yes, 2014
Aziridinomitosenes (AZMs) are organic compounds structurally related to the mitomycins, a class of anti-tumor agents and antibiotics. The cytotoxicity of the mitomycins is correlated to their ability to covalently link complimentary strands of DNA ...
Mallory, Christopher M.
core   +1 more source

Effects of Extremely Low Frequency Magnetic Field Exposure (50 Hz, 200 µT) on Cell Viability, DNA Damage and Micronucleus Formation of Human Skin Cells

open access: yesBioelectromagnetics, Volume 47, Issue 2, February 2026.
ABSTRACT Both everyday electrical devices and high voltage transmission lines produce electric and magnetic fields with a frequency of 50 Hz in Europe and most other countries. Although several studies have already been investigating the effects of extremely low frequency magnetic field (ELF‐MF) exposure on biological material, this topic is still ...
Vivian Meyer   +3 more
wiley   +1 more source

Adverse Renal Outcomes in Patients With Mesothelioma—A Territory‐Wide Real‐World Data

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Introduction Advances in mesothelioma management have translated into longer patient survival and different treatment‐related side effects including nephrotoxicity. The risk of developing adverse renal outcomes in patients with mesothelioma and associated risk factors remains undefined.
Wang Chun Kwok   +3 more
wiley   +1 more source

Photobiomodulation and Radio‐Epithelitis in Anal Carcinoma: A Case‐Report and Clinical Reflection on Emerging Preventive and Supportive Care Modalities

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Radio‐induced dermatitis, a frequent adverse effect of radiation therapy, is particularly prevalent in patients treated for anal margin carcinoma. It may present with varying severity, causing significant pain and impairment of daily mobility, influenced by both patient‐related factors and treatment regimens.
Michèle Pelletier‐Aouizerate   +1 more
wiley   +1 more source

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