Results 81 to 90 of about 1,470 (180)

AI‐assisted design of a VEGFR2 agonistic peptide that promotes angiogenesis and wound repair

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Vascular endothelial growth factor (VEGF) serves as a principal regulator of neovascularization and is essential for vascular regeneration. In this study, we identified and evaluated VEGF Mimetic Peptide3 (VMP3), a novel synthetic peptide developed as a potential VEGFR‐2/VEGF‐A modulator.
Farzana Yasmeen, Rajath Ramachandran, Rameez Hassan Pirzada, Bogeum Choi, Hana Seo, Wook Kim, Moon Suk Kim, Sangdun Choi   +7 more
wiley   +1 more source

STEREOSELECTIVE INTRAMOLECULAR HETERO-DIELS-ALDER REACTIONS OF 1-OXA-1,3-BUTADIENES - SYNTHESIS OF NOVEL ANNELATED PYRROLO[1,2-A]INDOLES [PDF]

, 2005
14Novelclassesofpyrano-1,3-dioxane-,pyranopyrimidine-andpyranopyrazole-fusedpyrrolo[1,2-a]indolesaresynthesised via stereoselective intramolecular 1-oxa-1,3-butadiene hetero Diels 13Alder ...
BHUYAN , P J, BORAH , H N, BORUAH , R C, DEB , M L   +3 more
core  

Radiological Loco‐Regional Treatments for Cholangiocarcinoma: A Systematic Review of the Literature

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Cholangiocarcinoma (CCA) is the second most common primary liver cancer and is being diagnosed with increasing frequency worldwide. We performed a systematic review on radiofrequency (RFA), microwave (MWA), irreversible electroporation (IRE), trans‐arterial chemoembolization (TACE) and selective internal radiation therapy (SIRT) in CCA. Thirty‐
Dimitrios Pallas, Claudia Campani, Olivier Sutter, Pierre Nahon, Nathalie Ganne‐Carrié, Olivier Seror, Jean‐Charles Nault   +6 more
wiley   +1 more source

Precursor-Directed Biosynthesis of Azinomycin A and Related Metabolites by Streptomyces sahachiroi [PDF]

Azinomycins A and B are bioactive compounds produced by Streptomyces species. These naturally occurring antibiotics exhibit potent in vitro cytotoxic activity, promising in vivo antitumor activity and exert their effect by disruption of DNA replication ...
Sebbar, Abdel-Ilah
core   +2 more sources

Synthesis and biological evaluation of potential DNA cross-linking agents based on pyrrolizidine alkaloids [PDF]

, 2001
2001 Fall.Includes bibliographical references.DNA cross-linking agents represent one of the most potent categories of antitumor agents. Pyrrolizidine alkaloids are an abundant class of biologically active natural products.
Kosogof, Christi
core  

FNDC1 Competitively Binds Gβ2 to Suppress the β‐Catenin–Destruction Complex and Promote Gastric Cancer Malignancy

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
FNDC1 competitively binds Gβ2 to suppress the β‐catenin–destruction complex and promote the malignant behavior of gastric cancer (GC) by the following mechanism: elevated FNDC1 competes with Dvl for binding to Gβ2, thereby reducing Dvl–Gβ2 interaction; this reduction inhibits Dvl degradation in the cytoplasm; increased Dvl recruits Axin1, thereby ...
Wenyu Gao, Hao Chen, Fangyu Lin, Jialin Liu, Tingxuan Huang, Han Wang, Xiaojiao Weng, Xinli Wang, Xiaoyan Lin, Tao Jiang   +9 more
wiley   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

Der Effekt des Belichtungsregimes auf das Temperatur-Induzierte und spontane Ausbleichen von Euglena gracilis [PDF]

, 1970
Ustanovljeno je, da je postotak bezbojnih euglena (bilo nastalih spontano, bilo indukcijom kod povišene temperature) u kontinuirano osvijetljenim kulturama značajno povišen u odnosu na periodički osvijetljene kulture (14 h svjetlosti: 10 h tame).Es wird ...
Elena Marčenko
core   +1 more source

A Critical Analysis of the Impact of Etoposide as a Topoisomerase II Inhibitor in Cervical Cancer Treatment: A Review

Cancer Medicine, Volume 15, Issue 3, March 2026.
Etoposide mediated topoisomerase II inhibition in Cervical Cancer. ABSTRACT Background Etoposide is a semisynthetic derivative of podophyllotoxin and an FDA‐approved topoisomerase II inhibitor that induces DNA strand breaks leading to cancer cell death.
Nikitha Kotian, Yashaswini Reddy, Padmini Pai, Babitha Kampa Sundara   +3 more
wiley   +1 more source

A Novel Treatment for Outer Ear Keloids Using Rubber Band Ligation—From Rear to Ear

Clinical Case Reports, Volume 14, Issue 3, March 2026.
We present a novel treatment for outer ear keloids using rubber band ligation in 3 patients. ABSTRACT This study demonstrates the use of a rubber band ligation for treating outer ear keloids. The method is effective, safe, and well‐tolerated by the patients.
Johanna Sundén, Krister Tano, Anders Niklasson   +2 more
wiley   +1 more source