Results 81 to 90 of about 13,073 (205)

Advancements in Diagnostics and Therapeutics for Cancer of Unknown Primary in the Era of Precision Medicine

open access: yesMedComm, Volume 6, Issue 5, May 2025.
In clinical practice, routine examinations for patients with CUP include taking a medical history, conducting a physical examination, and detecting serum tumor markers. In addition, IHC or MTP‐based methodologies were suggested to assist in identifying the tissue origin of CUP and guiding site‐specific therapy for CUP.
Ting Zhao   +5 more
wiley   +1 more source

Sotorasib Is Not Effective in a KRAS‐Mutated Patient With Brain Metastases From Lung Adenocarcinoma due to Multiple Gene Co‐Mutations

open access: yesRespirology Case Reports, Volume 13, Issue 5, May 2025.
We report a case of brain metastasis that occurred during the standard post‐operative treatment for early‐stage NSCLC. Initial multiplex test was performed using the brain metastatic tissue, and the KRAS G12C mutation was detected. However, the response to Sotorasib treatment was not observed.
Takayuki Suetsugu   +9 more
wiley   +1 more source

STUDIES ON MITOMYCINS. III

open access: bronze, 1968
Masanao Matsui   +3 more
openalex   +2 more sources

Interleukin‐24: A Multidimensional Therapeutic for Treatment of Human Diseases

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 17, Issue 3, May/June 2025.
The discovery of interleukin (IL)‐24 and studying its biological activity demonstrate its potential to serve as a therapeutic for human diseases, especially for cancer treatment. Image created with BioRender.com. ABSTRACT The field of targeted therapy exploits the selective expression of therapeutic genes or proteins in diseased cells.
Rajeswari Raguraman   +2 more
wiley   +1 more source

Vinca alkaloids as a potential cancer therapeutics: recent update and future challenges. [PDF]

open access: yes3 Biotech, 2023
Banyal A   +6 more
europepmc   +1 more source

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