Results 221 to 230 of about 359,876 (283)

Coenzyme A mitigates cystine‐deprivation‐induced ferroptosis by suppressing the iron‐starvation response

The FEBS Journal, EarlyView.
Cystine (Cys2) deprivation in pancreatic cancer cells induces oxidative stress that destabilizes cytosolic iron–sulfur cluster (ISC) proteins, triggering an iron‐regulatory protein (IRP)‐mediated iron‐starvation response (ISR). This leads to increased iron uptake (via TFRC), an expanded labile iron pool, and ferroptosis.
Mingjun Tan, Yunzhan Li, Lei Sang, Min Wang, Qin Li, Zekun Li, Dongxiao Sun, Xiuchao Wang, Shengyu Yang   +8 more
wiley   +1 more source

PI-YOLO: dynamic sparse attention and lightweight convolutional based YOLO for vessel detection in pathological images. [PDF]

Front Oncol
Li C, Che S, Gong H, Ding Y, Luo Y, Xi J, Qi L, Zhang G.   +7 more
europepmc   +1 more source

Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism

The FEBS Journal, EarlyView.
Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna, Christoff Odendaal, Madhulika Singh, Albert Gerding, Miriam Langelaar‐Makkinje, Marianne van der Zwaag, Asmara Drachman, Vladimíra Cetkovská, Gaby Liem Foeng Kioen, Anne‐Claire M. F. Martines, Nicolette C. A. Huijkman, Hein Schepers, Bart van de Sluis, Dirk‐Jan Reijngoud, Ody C. M. Sibon, Amy C. Harms, Thomas Hankemeier, Barbara M. Bakker   +17 more
wiley   +1 more source

Health care resource utilization and costs across stages of amyotrophic lateral sclerosis in the United States. [PDF]

J Manag Care Spec Pharm
Stenson K, Chew S, Dong S, Heithoff K, Wang MJ, Rosenfeld J.   +5 more
europepmc   +1 more source

El mito euskera

Publicat a El Periódico.
openaire   +2 more sources

Fruit respiration: putting alternative pathways into perspective

New Phytologist, EarlyView.
Summary Over the past century, research has significantly advanced our understanding of fruit respiration, from (eco)physiological processes to molecular mechanisms. This review focuses on the functional relevance and regulatory roles of mitochondrial alternative respiratory pathways (ARPs) during fruit growth and ripening.
Ariadna Iglesias‐Sanchez, Sergio García‐Carbonell, Alisdair R. Fernie, Marta Pujol, Igor Florez‐Sarasa   +4 more
wiley   +1 more source

Natural Variation of a PPR Coding Gene SST1 Confers Salt Tolerance During Soybean Domestication

Plant Biotechnology Journal, EarlyView.
ABSTRACT Soil salinity is one of the constraints that adversely affect seedling growth and limit soybean yield. Identifying salt tolerance genes and profiling their allele variants are crucial for elucidating the mechanisms underlying salt tolerance in soybean and enabling the genetic improvement of salt‐tolerant cultivars.
Hui Wang, Huifang Yuan, Yadi Wang, Weikang Xi, Xiaodi Wang, Ruiheng Tang, Qi Xu, Jiaying Li, Dongxu Liu, Qingyong Yang, Xutong Wang, Fanjiang Kong, Baohui Liu, Xia Li, Zhijuan Wang   +14 more
wiley   +1 more source

The complete mitogenome of <i>Eriocrania semipurpurella alpina</i> Xu, 1990 (Lepidoptera: Eriocraniidae). [PDF]

Mitochondrial DNA B Resour
Zhang X, Feng W, Hou Q.
europepmc   +1 more source

Multi‐Omics Combined With Mitochondrial Feeding Assays Reveal a Novel Energy Metabolism Strategy for Floral Thermogenesis in Magnolia Driven by Synergistic Supply of Multiple Substrates

Plant Biotechnology Journal, EarlyView.
ABSTRACT The high demand for energy during floral thermogenesis drives the synergistic operation of multiple energy substrates for the rapid temperature rise and successful reproduction of flowers. However, how thermogenic plants precisely regulate substrate supply and metabolic pathways within a short time to support large‐scale energy and heat ...
Siqin Wang, Jiying Li, Zhang Wang, Miao Yu, Chang Liu, Dongye Liu, Ruohan Wang   +6 more
wiley   +1 more source

A Line-Source Approach for Simulating MammoWave Microwave Imaging Apparatus for Breast Lesion Detection. [PDF]

Sensors (Basel)
Ghavami N, Dudley S, Ghavami M, Tiberi G.   +3 more
europepmc   +1 more source