Results 231 to 240 of about 359,876 (283)

Salvia miltiorrhiza‐Derived Vesicle‐Like Nanoparticles Functionalised Hydrogel With Excellent Ability of Oxidative Stress Modulation and Anti‐Cardiomyocyte Apoptosis for Sepsis‐Induced Myocardial Injury

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT In the process of myocardial cell structural and functional damage caused by various factors, current therapeutic strategies primarily focus on restoring myocardial blood supply, often neglecting the inherent complex microenvironment triggered by elevated reactive oxygen species (ROS) levels during myocardial injury.
Zhichao Liu   +12 more
wiley   +1 more source

Nanoengineered photosensitizers for photodynamic priming to overcome P‐glycoprotein‐mediated multidrug resistance

open access: yesPhotochemistry and Photobiology, EarlyView.
Verteporfin's subcellular localization governs its ability to deplete ATP. LysoPC‐conjugated VP accumulates in lysosomes and spares mitochondria, while liposomal and NanoVP formulations target mitochondria, where light activation triggers membrane depolarization and ATP depletion, overcoming resistance seen with free‐form VP. Abstract P‐glycoprotein (P‐
Idrisa Rahman   +7 more
wiley   +1 more source

Weak Nuclear Divergence Despite Pronounced Mitochondrial Divergence Within a Widespread Desert‐Inhabiting Palearctic Lark (Aves: Alaudidae)

open access: yesZoologica Scripta, EarlyView.
ABSTRACT The Bar‐tailed Lark Ammomanes cinctura is a polytypic bird species with a wide distribution. One of its three subspecies, A. c. arenicolor, has previously been found to show deep mitochondrial divergence between its geographically most distant populations, from Morocco and Saudi Arabia, respectively.
Zongzhuang Liu   +9 more
wiley   +1 more source

The Role of Gene Flow in the Diversification of the Monkey Treefrog Complex Across the South American Dry Diagonal

open access: yesZoologica Scripta, EarlyView.
ABSTRACT Understanding Neotropical megadiversity remains challenging due to fundamental taxonomic issues, including identifying and describing cryptic species and their distribution, and the limited knowledge of key factors driving biological diversification. Such challenges are especially prominent in diverse clades with high levels of cryptic species,
Felipe Camurugi   +10 more
wiley   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

open access: yesExperimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti   +6 more
wiley   +1 more source

Immune checkpoint changes correlate with the progression and prognosis of amyotrophic lateral sclerosis. [PDF]

open access: yesAnn Med
Chen S   +10 more
europepmc   +1 more source

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