Results 231 to 240 of about 329,783 (340)

Truncated FOS impairs osteogenic differentiation and induces prostaglandin and NFκB signalling in an in vitro cell‐of‐origin model for osteoid osteoma and osteoblastoma

The Journal of Pathology, EarlyView.
Abstract Osteoid osteoma and osteoblastoma are non‐malignant bone‐forming tumours of the skeleton, characterised by the presence of irregular trabeculae of woven bone. Rearrangements in FOS, and less frequently FOSB, have recently been identified in osteoid osteoma and osteoblastoma.
Suk Wai Lam, Tatiana Belova, Natasja Franceschini, Brendy van den Akker, David GP van IJzendoorn, Harald MM Mikkers, Hailiang Mei, Anne‐Marie Cleton‐Jansen, Marieke L Kuijjer, Karoly Szuhai, Judith VMG Bovée   +10 more
wiley   +1 more source

CIP2A mediates mitotic recruitment of SLX4/MUS81/XPF to resolve replication stress-induced DNA lesions. [PDF]

Nat Commun
de Haan L, Dijt SJ, García-López A, Ruan D, Martzios P, Bakker FJ, Everts M, Warner H, Mol FN, Chapman JR, de Boer HR, van de Kooij B, Huis In 't Veld PJ, Vlijm R, van Vugt MATM.   +14 more
europepmc   +1 more source

A Two-Stage Strategy for Mitosis Detection Using Improved YOLO11x Proposals and ConvNeXt Classification [PDF]

Jie Xiao, Mengye Lyu, Shaojun Liu
openalex   +1 more source

Integrating artificial intelligence (AI) into colorectal cancer reporting

The Journal of Pathology, EarlyView.
Abstract Artificial intelligence (AI) and deep learning (DL) are transforming cancer research and clinical care, with histopathology playing a central role in this transformation. In colorectal cancer (CRC), the second leading cause of cancer mortality world‐wide, multimodal and vision‐language models (VLMs) hold particular promise for enhancing the ...
Konstantin Bräutigam, Ann‐Marie Baker, Viktor H Koelzer, Jakob N Kather, Trevor A Graham   +4 more
wiley   +1 more source

Actin Takes the Steering Wheel: A New Mitotic Safeguard in the Early Embryo. [PDF]

Research (Wash D C)
Zhang Y, Zhu S, Wang F.
europepmc   +1 more source

The Relationship of Histone Phosphorylation to Deoxyribonucleic Acid Replication and Mitosis during the HeLa S-3 Cell Cycle

, 1973
Dawn B. Marks, Woon Ki Paik, Thaddeus W. Borun   +2 more
openalex   +1 more source

Oncogenic H‐Ras Reprograms Madin‐Darby Canine Kidney (MDCK) Cell‐Derived Midbody Remnant Proteome Following Epithelial‐Mesenchymal Transition

PROTEOMICS, EarlyView.
ABSTRACT Epithelial‐mesenchymal transition (EMT) is a fundamental, dynamic cellular process involved in embryonic development, metastasis, organ fibrosis, and tissue regeneration. To define the molecular landscape of secreted midbody remnants (MBRs) to the EMT process, a proteome analysis of MBRs released from Madin–Darby canine kidney (MDCK) cells and
Adnan Shafiq, Alin Rai, Rong Xu, Maoshan Chen, Wittaya Suwakulsiri, David W. Greening, Richard J. Simpson   +6 more
wiley   +1 more source

Spatial Chromatin Organization Across the Cell Cycle: Insights from Auxin-Inducible Protein Depletion. [PDF]

Cells
Nurislamov A, Yunusova A.
europepmc   +1 more source

Computational Characterization of the Role of LEM2/LaminA Interactions on the Stability of BAF‐Dimer Using Molecular Simulations

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The effect of the presence of the BAF‐binding LEM‐domain and LaminA Ig‐fold on the stability of the BAF dimer was studied qualitatively using non‐equilibrium pull simulations and quantitatively through the calculation of the potential of mean force profile along BAF–BAF separation distance.
Aswin Vinod Muthachikavil, Alexander von Appen, Thomas D. Kühne   +2 more
wiley   +1 more source

A busy BOD1-y: the diverse functions of an intracellular signaling regulatory protein family. [PDF]

Biochem Soc Trans
Kucharski TJ, Higgs MR, Compton DA, Bechstedt S.   +3 more
europepmc   +1 more source