Results 231 to 240 of about 163,907 (337)

Efficacy and biomarker analysis of neoadjuvant disitamab vedotin (RC48‐ADC) combined immunotherapy in patients with muscle‐invasive bladder cancer: A multi‐center real‐world study

open access: yesiMeta, EarlyView.
In this study, 102 cisplatin‐ineligible patients with muscle‐invasive bladder cancer (MIBC) who received neoadjuvant RC48‐ADC combined with immunotherapy were included. We evaluated the pathological responses and explored multiple clinical characteristics to identify independent predictive indicators of the efficacy. The results showed that neoadjuvant
Jiao Hu   +33 more
wiley   +1 more source

Mitotic chromatin marking governs the segregation of DNA damage. [PDF]

open access: yesNat Commun
Ferrand J   +7 more
europepmc   +1 more source

Efficacy of Haloxyfop‐R‐Methyl on Allium cepa: Cyto‐Genotoxic and In Silico Docking Studies on the Mechanism of Action

open access: yesMicroscopy Research and Technique, EarlyView.
ABSTRACT Haloxyfop‐R‐methyl (HRM) is extensively employed to control annual and perennial grass weeds. This study aimed to investigate the cyto‐genotoxic effects of HRM at concentrations of 1.19, 2.38, and 4.76 mg/L over various time intervals (24, 48, 72, and 96 h) on Allium cepa root.
Recep Liman   +4 more
wiley   +1 more source

Cardiovascular Mitosis

open access: yesStructural Heart
Anthony DeMaria, MD
doaj  

SRBD1 facilitates chromosome segregation by promoting topoisomerase IIα localization to mitotic chromosomes. [PDF]

open access: yesNat Commun
Lovejoy CA   +6 more
europepmc   +1 more source

Light and Electron Microscope Observations of the Male Reproductive Organs of Adult Julodis ehrenbergii Laporte (Coleoptera, Buprestidae)

open access: yesMicroscopy Research and Technique, EarlyView.
This study is about the male reproductive organs of Julodis ehrenbergii. To determine morphological and histological characters was used light and scanning electron microscopy were used. The investigation revealed testes, vasa deferentia, accessory glands, and ductus ejaculatorius structures.
Damla Amutkan Mutlu   +3 more
wiley   +1 more source

Comparative structural insights and functional analysis for the distinct unbound states of Human AGO proteins. [PDF]

open access: yesSci Rep
Kakoulidis P   +6 more
europepmc   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Multimodal mechanisms of human centriole engagement and disengagement. [PDF]

open access: yesEMBO J
Ito KK   +9 more
europepmc   +1 more source

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