Results 241 to 250 of about 229,134 (290)
Phosphorylation and chromatin tethering prevent cGAS activation during mitosis
Science, 2021 Keeping cGAS silent Cells detect microbial and self-DNA in the cytosol as a danger signal that triggers immune and inflammatory responses. Paradoxically, a large fraction of a DNA-sensing enzyme called cGAS is tightly associated with the chromatin ...
Tuo Li, Tuozhi Huang, Mingjian Du
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Actin cables and comet tails organize mitochondrial networks in mitosis
Nature, 2021 Symmetric cell division requires the even partitioning of genetic information and cytoplasmic contents between daughter cells. Whereas the mechanisms coordinating the segregation of the genome are well known, the processes that ensure organelle ...
Andrew S Moore +2 more
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Chromatin structure dynamics during the mitosis-to-G1 phase transition
Nature, 2019 Features of higher-order chromatin organization—such as A/B compartments, topologically associating domains and chromatin loops—are temporarily disrupted during mitosis1,2.
Haoyue Zhang +2 more
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Kinase-controlled phase transition of membraneless organelles in mitosis
Nature, 2018Jia-Xuan Chen +2 more
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DNA breaks and chromosome pulverization from errors in mitosis
Nature, 2012 The involvement of whole-chromosome aneuploidy in tumorigenesis is the subject of debate, in large part because of the lack of insight into underlying mechanisms. Here we identify a mechanism by which errors in mitotic chromosome segregation generate DNA
Karen Crasta, Neil J Ganem, Luigi Nezi
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The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis
Nature Reviews Molecular Cell Biology, 2012 Mar Carmena, Hironori Funabiki
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Science, 1989
Data that describe both the structure and the physiology of the mitotic spindle are reviewed. Some of the molecules that have been shown to play a role in mitosis are tabulated, and how mitosis might work is considered.
J R, McIntosh, M P, Koonce
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Data that describe both the structure and the physiology of the mitotic spindle are reviewed. Some of the molecules that have been shown to play a role in mitosis are tabulated, and how mitosis might work is considered.
J R, McIntosh, M P, Koonce
openaire +2 more sources
BioEssays, 1994
AbstractWithin the last decade, the study of mitosis has evolved into a multidisciplinary science in which findings from fields as diverse as chromosome biology and cytoskeletal architecture have converged to present a more cohesive understanding of the complex events that occur when cells divide.
W C, Earnshaw, A F, Pluta
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AbstractWithin the last decade, the study of mitosis has evolved into a multidisciplinary science in which findings from fields as diverse as chromosome biology and cytoskeletal architecture have converged to present a more cohesive understanding of the complex events that occur when cells divide.
W C, Earnshaw, A F, Pluta
openaire +2 more sources
A changing paradigm of transcriptional memory propagation through mitosis
Nature Reviews Molecular Cell Biology, 2018 Katherine C Palozola +2 more
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Weakly supervised mitosis detection in breast histopathology images using concentric loss
Medical Image Anal., 2019HighlightsAn automatic and accurate system for detecting mitosis in histopathology images.Our method utilizes a deep segmentation network to produce segmentation map.
C. Li +5 more
semanticscholar +1 more source