Results 251 to 260 of about 329,783 (340)

Introducing Epigenetics Into Secondary School Classrooms—An Educational Design Study

Science Education, EarlyView.
ABSTRACT Although epigenetics represents an emerging field of biological research with a potentially large influence on society as well as conceptual implications on how genetics is understood, it is often not a part of the biology education provided at secondary schools.
Karin Thörne, Niklas Gericke, Birgitta Mc Ewen   +2 more
wiley   +1 more source

Epigenetic Regulation of Chromosomal Instability by EZH2 Methyltransferase. [PDF]

Cancer Discov
Bai Y, Agustinus AS, Yomtoubian S, Meydan C, McNally DR, Yoffe L, Hubisz MJ, Tranquille M, Pramod S, Hong C, Plasilova ML, Kapoor AR, Singh A, Withers H, Dow LE, Laughney AM, Bhinder B, Elemento O, Melnick AM, Bakhoum SF, Mittal V.   +20 more
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

A mitotic bookmark coordinates transcription and replication in Drosophila embryos. [PDF]

Nucleic Acids Res
Cho CY, O'Farrell PH.
europepmc   +1 more source

Mitosis [PDF]

Nature, 1945
openaire   +1 more source

Evidence for Drop‐Like Nuclear Deformation in Sheared Endothelial Monolayers

Small, EarlyView.
Physiological shear stress smoothens endothelial monolayers by selectively eliminating less‐spread cells with tall, wrinkled nuclei. Nuclear volume and surface area remain constant, consistent with drop‐like deformation governed by geometric constraints.
Mohammad Mohajeri, Ting‐Ching Wang, Pooja Agarwal, Simran Kaur, Ankit Kumar, Richard B. Dickinson, Abhishek Jain, Tanmay P. Lele   +7 more
wiley   +1 more source

Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer. [PDF]

Elife
Armand J, Kim S, Kim K, Son E, Kim M, Kalinsky K, Yang HW.   +6 more
europepmc   +1 more source

Fluorophore Modulates Intracellular Distribution of Enzyme‐Instructed Self‐Assembly of Short Peptides in Osteosarcoma Cells

Small Methods, EarlyView.
Fluorophores at the peptide C‐terminus reprogram EISA behavior in osteosarcoma cellsshifting ER vs mitochondrial targeting, altering assembly, and tuning cytotoxicity. Abstract Enzyme‐instructed self‐assembly (EISA) of peptides offers a versatile strategy for developing intracellular nanomedicines, yet the role of C‐terminus fluorophores in modulating ...
Yali Huang, Meihui Yi, Yuchen Qiao, Bing Xu   +3 more
wiley   +1 more source

Phosphatase specificity influences phosphorylation timing of CDK substrates during the cell cycle. [PDF]

Nat Commun
Zeisner TU, Auchynnikava T, Roberts EL, Nurse P.   +3 more
europepmc   +1 more source

[Mitosis].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1967
openaire   +1 more source