Results 251 to 260 of about 380,556 (390)

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

The Silent Spread: A Systematic Review of Delayed Melanoma Diagnosis and Disease Progression During the COVID‐19 Pandemic

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background The COVID‐19 pandemic has significantly disrupted global healthcare systems. Melanoma, a highly aggressive skin cancer whose prognosis is closely tied to early detection, has been particularly impacted. Lockdowns, changes to healthcare resource reallocation and patient hesitancy in seeking care have all contributed to delays in ...
Akshay Soni   +5 more
wiley   +1 more source

WIP1 mutations suppress DNA damage triggered bypass of the mitotic timer. [PDF]

open access: yesEMBO J
Sobajima T   +5 more
europepmc   +1 more source

Hypoxia Triggers ALYREF‐Mediated m5C Methylation of KIF20A to Activate KIF20A/BUB1 for Generating Ferroptosis Resistance in Cervical Cancer Cells

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ferroptosis resistance is a key player in cervical cancer (CC) development. Hypoxia is a negative factor affecting CC treatment by inducing ferroptosis resistance. Our study aimed to investigate the detailed mechanisms of hypoxia‐induced ferroptosis resistance in CC cells.
Yan Gao, Ting Zou
wiley   +1 more source

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