Results 271 to 280 of about 386,071 (373)

Protein phosphatase 2A (PP2A) function in male germ cells and its importance for male fertility. [PDF]

Endocr Connect
Simon V.
europepmc   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

The CIP2A-TOPBP1 axis facilitates mitotic DNA repair via MiDAS and MMEJ. [PDF]

Nat Commun
Martin PR, Nieminuszczy J, Kozik Z, Jakub N, Kowalski S, Lecot M, Vorhauser J, Lane KA, Kanellou A, Mansfeld J, Pearl LH, Oliver AW, Downs JA, Choudhary JS, Day M, Niedzwiedz W.   +15 more
europepmc   +1 more source

The metabolic consequences of glucose-6-phosphate transporter (G6PT) depletion in mice and Investigating the role of transcriptional intermediary factor 1-γ (TIF1γ) in mitosis [PDF]

, 2013
Rachel Fletcher
openalex  

Mitosis Inhibits DNA Double-Strand Break Repair to Guard Against Telomere Fusions

Science, 2014
Alexandre Orthwein, Amélie Fradet-Turcotte, S. M. Noordermeer, M. Canny, C. Brun, Jonathan Strecker, Cristina Escribano-Díaz, D. Durocher   +7 more
semanticscholar   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

DNA damage in mitosis: SOD1 delays anaphase onset. [PDF]

FEBS J
Zachos G.
europepmc   +1 more source

Geminin, an Inhibitor of DNA Replication, Is Degraded during Mitosis

Cell, 1998
T. McGarry, M. Kirschner
semanticscholar   +1 more source

Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review

Rare Metals, EarlyView.
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu, Ding‐Hu Zhang, Chuan Hu, Yi‐Nan Ding, Kun Chen, Yi Jiang, Jun Luo, Fei Cao, Wei‐Yuan Hao, Bin‐Yan Zhong, Jie Lin, Dong Xu, Jia‐Ping Zheng   +12 more
wiley   +1 more source

Identification and functional evaluation of cyclin-dependent kinase genes reveals that CDKB1;1 and CDKB2;2 contribute to the balance of mitosis and endoreduplication in Medicago truncatula nodule. [PDF]

BMC Plant Biol
Wang R, Pan H.
europepmc   +1 more source