Results 271 to 280 of about 379,827 (391)

Evaluating AI-Based Mitosis Detection for Breast Carcinoma in Digital Pathology: A Clinical Study on Routine Practice Integration. [PDF]

Diagnostics (Basel)
Simmat C, Guichard L, Sockeel S, Pozin N, Peyret R, Lacroix-Triki M, Miquel C, Gauthier A, Sockeel M, Prévot S.   +9 more
europepmc   +1 more source

Rheology of the Active Cell Cortex in Mitosis.

Biophysical Journal, 2016
Elisabeth Fischer-Friedrich, Y. Toyoda, Cédric J. Cattin, D. Müller, A. Hyman, F. Jülicher   +5 more
semanticscholar   +1 more source

Covalent Inhibition of the Peptidyl‐Prolyl Isomerase Pin1 by Sulfopin Results in a Broad Impact on the Phosphoproteome of Human Osteosarcoma U2‐OS Cells

PROTEOMICS, EarlyView.
ABSTRACT Peptidyl‐prolyl isomerase, NIMA‐interacting protein 1‐(Pin1) catalyses the cis–trans interconversion of the inflexible bond between serine or threonine residues and proline at the +1 position (pSer/pThr‐Pro). Although initially discovered as an essential regulator of cell division, Pin1 has since been identified as a regulator of many ...
Scott E. Roffey, Owen Hovey, Kristina Jurcic, Kun Ping Lu, Xiao Zhen Zhou, David W. Litchfield   +5 more
wiley   +1 more source

Mechanistic insight into anaphase bridge signaling to the abscission checkpoint. [PDF]

EMBO J
Singh MI, Rajendraprasad G, Katopodis V, Cui R, Barisic M, Bhowmick R, Hickson ID.   +6 more
europepmc   +1 more source

Microtubule detyrosination guides chromosomes during mitosis

Science, 2015
M. Barišić, Ricardo Silva e Sousa, S. Tripathy, M. Magiera, Anatoly V. Zaytsev, A. L. Pereira, C. Janke, E. Grishchuk, H. Maiato   +8 more
semanticscholar   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Confinement in fibrous environments positions and orients mitotic spindles. [PDF]

PNAS Nexus
Sarkar A, Jana A, Agashe A, Wang J, Kapania R, Gov NS, DeLuca JG, Paul R, Nain AS.   +8 more
europepmc   +1 more source

The serine palmitoyl transferase of plant pathogenic fungi: a promising new target for the development of novel crop protection solutions†

Pest Management Science, EarlyView.
High biological activity of pyridazine carboxamides against a wide range of Ascomycetes led to identification of a new biochemical target for agrochemical fungicides – serine palmitoyl transferase. Abstract BACKGROUND Plant pathogens pose a significant threat to global agriculture and, thus to world food supplies, requiring the development of ...
Lionel Nicolas, Emilia Hilz, Stephanie Gamet, Vincent Thomas, Stephane Peyrard, Luigi Di Vietro, Benedicte Cirer, Julie Geist, Bernd Essigmann, Anne Ferry, Angeline Chanel, Frédéric Berniaud, Dominik Schwarz, Virginie Lempereur   +13 more
wiley   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Two cancer cell lines utilize Myosin 10 and the kinesin HSET differentially to maintain mitotic spindle bipolarity. [PDF]

PLoS One
Yim YI, Wu X, Gasilina A, Hammer JA.
europepmc   +1 more source