Results 61 to 70 of about 286,319 (230)
Improving mitosis detection on histopathology images using large vision-language models [PDF]
arXiv, 2023 In certain types of cancerous tissue, mitotic count has been shown to be associated with tumor proliferation, poor prognosis, and therapeutic resistance. Due to the high inter-rater variability of mitotic counting by pathologists, convolutional neural networks (CNNs) have been employed to reduce the subjectivity of mitosis detection in hematoxylin and ...
arxiv
Stressing Mitosis to Death [PDF]
Frontiers in Oncology, 2014 The final stage of cell division (mitosis), involves the compaction of the duplicated genome into chromatid pairs. Each pair is captured by microtubules emanating from opposite spindle poles, aligned at the metaphase plate, and then faithfully segregated to form two identical daughter cells. Chromatids that are not correctly attached to the spindle are
Andrew eBurgess +3 more
openaire +4 more sources
Cell Reports, 2014 Mitosis is a moment of exquisite vulnerability for a metazoan cell. Failure to complete mitosis accurately can lead to aneuploidy and cancer initiation.
Pengbo Wang +8 more
doaj +1 more source
Analysis of an HTLV/HIV dual infection model with diffusion
Mathematical Biosciences and Engineering, 2021 In the literature, several HTLV-I and HIV single infections models with spatial dependence have been developed and analyzed. However, modeling HTLV/HIV dual infection with diffusion has not been studied. In this work we derive and investigate a PDE model
A. M. Elaiw, N. H. AlShamrani
doaj +1 more source
Two-step Domain Adaptation for Mitosis Cell Detection in Histopathology Images [PDF]
arXiv, 2021 We propose a two-step domain shift-invariant mitosis cell detection method based on Faster RCNN and a convolutional neural network (CNN). We generate various domain-shifted versions of existing histopathology images using a stain augmentation technique, enabling our method to effectively learn various stain domains and achieve better generalization ...
arxiv
Cell DivisionIntroduction Anti-mitosis has been a key strategy of anti-cancer therapies, targeting at a fundamental property of cancer cells, their non-controllable proliferation due to overactive mitotic divisions. For improved anti-cancer therapies, it is important
Iram Shazia Tyagi +12 more
doaj +1 more source
Importance of the CEP215-pericentrin interaction for centrosome maturation during mitosis. [PDF]
PLoS ONE, 2014 At the onset of mitosis, the centrosome undergoes maturation, which is characterized by a drastic expansion of the pericentriolar material (PCM) and a robust increase in microtubule-organizing activity.
Seongjae Kim, Kunsoo Rhee
doaj +1 more source
Breakage of CRISPR/Cas9-Induced Chromosome Bridges in Mitotic Cells
Frontiers in Cell and Developmental Biology, 2021 Chromosomal instability, the most frequent form of plasticity in cancer cells, often proceeds through the formation of chromosome bridges. Despite the importance of these bridges in tumor initiation and progression, debate remains over how and when they ...
Marina Rodriguez-Muñoz +4 more
doaj +1 more source
Domain Adaptive Cascade R-CNN for MItosis DOmain Generalization (MIDOG) Challenge [PDF]
arXiv, 2021 We present a summary of the domain adaptive cascade R-CNN method for mitosis detection of digital histopathology images. By comprehensive data augmentation and adapting existing popular detection architecture, our proposed method has achieved an F1 score of 0.7500 on the preliminary test set in MItosis DOmain Generalization (MIDOG) Challenge at MICCAI ...
arxiv
Resetting a functional G1 nucleus after mitosis [PDF]
, 2016 © The Author(s) 2015. The maintenance of the correct cellular information goes beyond the simple transmission of an intact genetic code from one generation to the next. Epigenetic changes, topological cues and correct protein-protein interactions need to
De Castro, IJ, Gokhan, E, Vagnarelli, P
core +1 more source