Results 141 to 150 of about 4,840,174 (316)
Modern competency‐based teaching of human sexual development
Anatomical Sciences Education, EarlyView.Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler +2 more
wiley +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Chemistry – A European Journal, EarlyView.ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
Interaction Between Actin and Microtubules During Plant Development
Cytoskeleton, EarlyView.ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu +3 more
wiley +1 more source
Cell Death Response to DNA Damage. [PDF]
, 2019 The cell death response to DNA damage is discussed in this Perspectives piece with cancer as the backdrop because DNA damaging agents (DDA) are widely used to treat cancer.
Wang, Jean YJ
core +1 more source
PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana
Cytoskeleton, EarlyView.ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes +6 more
wiley +1 more source
Making Two out of One: Kinesin Motors Driving Plant Cell Division
Cytoskeleton, EarlyView.ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley +1 more source
Laser Microirradiation of Chinese Hamster Cells at Wavelength 365 nm [PDF]
, 1981 Cells of a V79 subline of the Chinese hamster were microirradiated at wavelength 365 nm in the presence of the psoralen derivative, trioxsalen. Microirradiation was accomplished by a pulsed argon laser microbeam either in anaphase or in interphase 3 hr ...
Berns, Michael W. +3 more
core
Cytoskeleton, EarlyView.ABSTRACT Pollen is a male gametophyte of angiosperms. Following meiosis, the microspore undergoes an asymmetric division called pollen mitosis I (PMI), which produces two cells of different sizes: a large vegetative cell and a small generative cell. Polarized nuclear migration and positioning during PMI are important for successful pollen development ...
Yoko Mizuta +5 more
wiley +1 more source
Loss of The RNA Helicase SKIV2L2 Impairs Mitotic Progression and Replication-Dependent Histone mRNA Turnover in Murine Cell Lines [PDF]
, 2017 RNA surveillance via the nuclear exosome requires cofactors such as the helicase SKIV2L2 to process and degrade certain noncoding RNAs. This research aimed to characterize the phenotype associated with RNAi knockdown of Skiv2l2 in two murine cancer cell ...
Anderson, James T. +1 more
core +1 more source